Regulation of p53 levels by the E1B 55-kilodalton protein and E4orf6 in adenovirus-infected cells. (Q35883364)

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2 November 2019

title

Regulation of p53 levels by the E1B 55-kilodalton protein and E4orf6 in adenovirus-infected cells (English)

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2 November 2019

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1

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2 November 2019

author name string

Marcellus RC

2

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2 November 2019

Lai A

3

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2 November 2019

Charbonneau R

4

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2 November 2019

Teodoro JG

5

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2 November 2019

Ketner G

6

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2 November 2019

Branton PE

7

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2 November 2019

language of work or name

English

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publication date

1 May 1997

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2 November 2019

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2 November 2019

volume

71

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2 November 2019

issue

5

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2 November 2019

page(s)

3788-3798

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Regulation of p53-dependent apoptosis, transcriptional repression, and cell transformation by phosphorylation of the 55-kilodalton E1B protein of human adenovirus type 5.

2 November 2019

cites work

1 reference

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Accumulation of p53 induced by the adenovirus E1A protein requires regions involved in the stimulation of DNA synthesis.

11 July 2018

1 reference

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Oncogenic potential of the adenovirus E4orf6 protein

11 July 2018

1 reference

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Translational regulation of human p53 gene expression.

11 July 2018

1 reference

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Adenovirus type 5 early region 4 is responsible for E1A-induced p53-independent apoptosis

11 July 2018

1 reference

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11 July 2018

p53: puzzle and paradigm

1 reference

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Blockage by adenovirus E4orf6 of transcriptional activation by the p53 tumor suppressor

11 July 2018

1 reference

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Control of p53 expression by adenovirus 12 early region 1A and early region 1B 54K proteins

11 July 2018

1 reference

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Induction of the cell cycle in baby rat kidney cells by adenovirus type 5 E1A in the absence of E1B and a possible influence of p53.

11 July 2018

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Adenovirus early region 4 and viral DNA synthesis

11 July 2018

1 reference

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p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

11 July 2018

1 reference

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Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.

11 July 2018

1 reference

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Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis

11 July 2018

1 reference

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Adenovirus E1B oncoprotein tethers a transcriptional repression domain to p53.

11 July 2018

1 reference

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The adenovirus E4-6/7 protein transactivates the E2 promoter by inducing dimerization of a heteromeric E2F complex

11 July 2018

1 reference

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Phosphorylation at the carboxy terminus of the 55-kilodalton adenovirus type 5 E1B protein regulates transforming activity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191529

Role of membrane anchor domain of Bcl-2 in suppression of apoptosis caused by E1B-defective adenovirus.

11 July 2018

1 reference

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Functional complementation of the adenovirus E1B 19-kilodalton protein with Bcl-2 in the inhibition of apoptosis in infected cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191529

Enhanced expression of p53 in human cells infected with mutant adenoviruses

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191529

Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191529

p53-independent apoptotic and necrotic cell deaths induced by adenovirus infection: suppression by E1B 19K and Bcl-2 proteins.

11 July 2018

1 reference

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Lack of correlation between p53 protein level and sensitivity of DNA-damaging agents in keratinocytes carrying adenovirus E1a mutants

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191529

The high levels of p53 present in adenovirus early region 1-transformed human cells do not cause up-regulation of MDM2 expression.

11 July 2018

1 reference

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Negative feedback regulation of wild-type p53 biosynthesis.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191529

Adenovirus early region 1B 58,000-dalton tumor antigen is physically associated with an early region 4 25,000-dalton protein in productively infected cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191529

A cell line that supports the growth of a defective early region 4 deletion mutant of human adenovirus type 2

11 July 2018

1 reference

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Adenovirus type 5 early region 1b gene product is required for efficient shutoff of host protein synthesis.

11 July 2018

1 reference

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Transformation properties of type 5 adenovirus mutants that differentially express the E1A gene products

11 July 2018

1 reference

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Establishment and characterization of a cloned line of C3H mouse embryo cells sensitive to postconfluence inhibition of division

11 July 2018

1 reference

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Adenovirus early region 4 encodes functions required for efficient DNA replication, late gene expression, and host cell shutoff

11 July 2018

1 reference

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Monoclonal antibodies specific for adenovirus early region 1A proteins: extensive heterogeneity in early region 1A products

11 July 2018

1 reference

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Adenoviral early region 4 is required for efficient viral DNA replication and for late gene expression

11 July 2018

1 reference

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Analysis of adenovirus early region 4-encoded polypeptides synthesized in productively infected cells

11 July 2018

1 reference

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The adenovirus E1B-55K transforming polypeptide modulates transport or cytoplasmic stabilization of viral and host cell mRNAs

11 July 2018

1 reference

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Adenovirus serotype determines association and localization of the large E1B tumor antigen with cellular tumor antigen p53 in transformed cells

11 July 2018

1 reference

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Adenovirus E1B proteins are required for accumulation of late viral mRNA and for effects on cellular mRNA translation and transport

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191529

Redundant control of adenovirus late gene expression by early region 4

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191529

Adenovirus early region 4 is essential for normal stability of late nuclear RNAs

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191529

The adenovirus E1B 55 kd protein influences mRNA transport via an intranuclear effect on RNA metabolism

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191529

Domains required for in vitro association between the cellular p53 and the adenovirus 2 E1B 55K proteins.

11 July 2018

1 reference

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Dissection of functional domains in the adenovirus 2 early 1B 55K polypeptide by suppressor-linker insertional mutagenesis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191529

Retinoblastoma growth suppressor and a 300-kDa protein appear to regulate cellular DNA synthesis

11 July 2018

1 reference

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Transactivation of the p53 oncogene by E1a gene products

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191529

Association between the cellular p53 and the adenovirus 5 E1B-55kd proteins reduces the oncogenicity of Ad-transformed cells.

11 July 2018

1 reference

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Interaction of adenoviral E4 and E1b products in late gene expression

11 July 2018

1 reference

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Transcriptional and Transforming Activities of the Adenovirus E1A Proteins

11 July 2018

1 reference

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Individual adenovirus E1B proteins induce transformation independently but by additive pathways

11 July 2018

1 reference

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Localization of the adenovirus early region 1B 55-kilodalton protein during lytic infection: association with nuclear viral inclusions requires the early region 4 34-kilodalton protein

11 July 2018

1 reference

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p53 point mutation in HPV negative human cervical carcinoma cell lines

11 July 2018

1 reference

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Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein

11 July 2018

1 reference

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Effects of Ad5 E1A mutant viruses on the cell cycle in relation to the binding of cellular proteins including the retinoblastoma protein and cyclin A

11 July 2018

1 reference

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The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins

11 July 2018

1 reference

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Characteristics of a human cell line transformed by DNA from human adenovirus type 5

11 July 2018

1 reference

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Host-range mutants of adenovirus type 5 defective for growth in HeLa cells

11 July 2018

1 reference

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Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells

11 July 2018

1 reference

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Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

11 July 2018

1 reference

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Overexpression of wild-type p53 and c-Myc in human fetal cells transformed with adenovirus early region 1.

11 July 2018

1 reference

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Two adenovirus proteins with redundant activities in virus growth facilitates tripartite leader mRNA accumulation

24 September 2018

1 reference

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A monoclonal antibody detecting the adenovirus type 5-E1b-58Kd tumor antigen: characterization of the E1b-58Kd tumor antigen in adenovirus-infected and -transformed cells

24 September 2018

1 reference

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Resolving the functions of overlapping viral genes by site-specific mutagenesis at a mRNA splice site

24 September 2018

1 reference

12 December 2020

Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells

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12 December 2020

The kinetics of synthesis of early viral proteins in KB cells infected with wild-type and transformation-defective host-range mutants of human adenovirus type 5

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12 December 2020

The metabolism of host RNAs in cells infected by an adenovirus E4 mutant

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12 December 2020

Adenovirus E1A proteins induce apoptosis by both p53-dependent and p53-independent mechanisms

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12 December 2020

Expression of p53 in Saos-2 osteosarcoma cells induces apoptosis which can be inhibited by Bcl-2 or the adenovirus E1B-55 kDa protein

1 reference

12 December 2020

Identifiers

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2 November 2019

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