One oxidant, many pathways: a theoretical perspective of monooxygenation mechanisms by cytochrome P450 enzymes. (Q35886758)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15365903%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

review article

1 reference

title

One oxidant, many pathways: a theoretical perspective of monooxygenation mechanisms by cytochrome P450 enzymes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15365903%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15365903%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

author name string

Sason Shaik

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15365903%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Devesh Kumar

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15365903%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

publication date

28 July 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15365903%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Inorganic Chemistry

1 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15365903%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15365903%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15365903%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

page(s)

661-668

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15365903%20AND%20SRC:MED&resulttype=core&format=json

Kinetic isotope effects implicate two electrophilic oxidants in cytochrome p450-catalyzed hydroxylations

1 January 2020

cites work

1 reference

12 December 2020

Can a single oxidant with two spin states masquerade as two different oxidants? A study of the sulfoxidation mechanism by cytochrome p450

1 reference

12 December 2020

How do aldehyde side products occur during alkene epoxidation by cytochrome P450? Theory reveals a state-specific multi-state scenario where the high-spin component leads to all side products

1 reference

12 December 2020

Aliphatic hydroxylation by highly purified liver microsomal cytochrome P-450. Evidence for a carbon radical intermediate

1 reference

12 December 2020

The elusive oxidant species of cytochrome P450 enzymes: characterization by combined quantum mechanical/molecular mechanical (QM/MM) calculations

1 reference

12 December 2020

First direct evidence for stereospecific olefin epoxidation and alkane hydroxylation by an oxoiron(IV) porphyrin complex

1 reference

12 December 2020

Quantum mechanical/molecular mechanical investigation of the mechanism of C-H hydroxylation of camphor by cytochrome P450cam: theory supports a two-state rebound mechanism

1 reference

12 December 2020

The bioinorganic chemistry of iron in oxygenases and supramolecular assemblies

1 reference

12 December 2020

Heme-Containing Oxygenases

1 reference

12 December 2020

Spectroscopic studies of peroxyacetic acid reaction intermediates of cytochrome P450cam and chloroperoxidase

1 reference

12 December 2020

Hydroxylation of camphor by reduced oxy-cytochrome P450cam: mechanistic implications of EPR and ENDOR studies of catalytic intermediates in native and mutant enzymes

1 reference

12 December 2020

The catalytic pathway of cytochrome p450cam at atomic resolution

1 reference

12 December 2020

Kinetic characterization of compound I formation in the thermostable cytochrome P450 CYP119.

1 reference

12 December 2020

High-valent intermediates of heme proteins and model compounds

1 reference

12 December 2020

A proton-shuttle mechanism mediated by the porphyrin in benzene hydroxylation by cytochrome p450 enzymes.

1 reference

12 December 2020

Epoxidation of olefins by hydroperoxo-ferric cytochrome P450.

1 reference

12 December 2020

Radical clock substrates, their C-H hydroxylation mechanism by cytochrome P450, and other reactivity patterns: what does theory reveal about the clocks' behavior?

1 reference

12 December 2020

Searching for the second oxidant in the catalytic cycle of cytochrome P450: a theoretical investigation of the iron(III)-hydroperoxo species and its epoxidation pathways

1 reference

12 December 2020

Nonheme FeIVO complexes that can oxidize the C-H bonds of cyclohexane at room temperature.

1 reference

12 December 2020

Transition-metal systems in biochemistry studied by high-accuracy quantum chemical methods

1 reference

12 December 2020

Chloroperoxidase compound I: electron paramagnetic resonance and Moessbauer studies

1 reference

12 December 2020

First success of catalytic epoxidation of olefins by an electron-rich iron(III) porphyrin complex and H2O2: imidazole effect on the activation of H2O2 by iron porphyrin complexes in aprotic solvent

1 reference

12 December 2020

X-ray crystal structure and catalytic properties of Thr252Ile mutant of cytochrome P450cam: roles of Thr252 and water in the active center

1 reference

12 December 2020

Hypersensitive radical probes and the mechanisms of cytochrome P450-catalyzed hydroxylation reactions

1 reference

12 December 2020

Hydroxylation by the hydroperoxy-iron species in cytochrome P450 enzymes

1 reference

12 December 2020

How Does Ethene Inactivate Cytochrome P450 En Route to Its Epoxidation? A Density Functional Study The research is supported in part by the ISF and in part by the Ministry of Science, Culture, and Sport. F.O. acknowledges the European Union for a Ma

1 reference

12 December 2020

10.1007/S00775-004-0576-6

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15365903%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference