Pharmacokinetics of [18F]fleroxacin in healthy human subjects studied by using positron emission tomography (Q35897375)

11 August 2017

Pharmacokinetics of [18F]fleroxacin in healthy human subjects studied by using positron emission tomography (English)

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human subject research project

11 August 2017

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Fischman AJ

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Livni E

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Babich J

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Alpert NM

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Liu YY

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Thom E

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Cleeland R

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Prosser BL

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Correia JA

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Strauss HW

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language of work or name

English

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publication date

1 October 1993

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Antimicrobial Agents and Chemotherapy

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11 August 2017

37

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10

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2144-2152

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describes a project that uses

11 August 2017

positron emission tomography

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Pharmacokinetics of gyrase inhibitors, Part 1: Basic chemistry and gastrointestinal disposition.

inferred from title

cites work

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Determination of object contour from projections for attenuation correction in cranial positron emission tomography

11 July 2018

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Clinical efficacy and tolerance of fleroxacin in patients with urethritis caused by Chlamydia trachomatis

11 July 2018

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Fleroxacin in single dose oral therapy of uncomplicated lower urinary tract infection

11 July 2018

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In-vitro activity of fleroxacin compared with three other quinolones

11 July 2018

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Pharmacokinetics and tissue penetration of fleroxacin after single and multiple 400- and 800-mg-dosage regimens

11 July 2018

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Single- and multiple-dose pharmacokinetics of fleroxacin, a trifluorinated quinolone, in humans

11 July 2018

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Comparative in vitro activity of RO 23-6240 (fleroxacin), a new 4-quinolone derivative

11 July 2018

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Fleroxacin (Ro 23-6240) distribution in canine prostatic tissue and fluids

11 July 2018

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Pharmacokinetics and tissue penetration of Ro 23-6240, a new trifluoroquinolone

11 July 2018

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Pharmacokinetics of a new quinolone, AM-833, in mice, rats, rabbits, dogs, and monkeys

11 July 2018

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In-vitro and in-vivo antibacterial activity of fleroxacin, a new fluorinated quinolone.

11 July 2018

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Dose-ranging study of fleroxacin for treatment of uncomplicated Chlamydia trachomatis genital infections

11 July 2018

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The pharmacokinetics and therapeutic efficacy of fleroxacin and pefloxacin in a rat abscess model

11 July 2018

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In vitro activity of fleroxacin and 14 other antimicrobials against slime- and non-slime-producing Staphylococcus epidermidis

11 July 2018

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Evaluation of fleroxacin (RO 23-6240) as single-oral-dose therapy of culture-proven chancroid in Nairobi, Kenya

11 July 2018

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Efficacy of fleroxacin in experimental methicillin-resistant Staphylococcus aureus endocarditis

11 July 2018

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Pharmacokinetics and biliary concentrations of fleroxacin in cholecystectomized patients

11 July 2018

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In vivo tissue pharmacokinetics by fluorine magnetic resonance spectroscopy: a study of liver and muscle disposition of fleroxacin in humans

11 July 2018

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Safety of fleroxacin coadministered with theophylline to young and elderly volunteers

11 July 2018

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In vivo evaluation of a dual-action antibacterial, Ro 23-9424, compared to cefotaxime and fleroxacin.

11 July 2018

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Bacteriological and clinical studies on fleroxacin in male gonococcal urethritis

11 July 2018

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Comparison of the effect of temafloxacin, ciprofloxacin, or placebo on cerebral blood flow, glucose, and oxygen metabolism in healthy subjects by means of positron emission tomography

11 July 2018

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Susceptibility of Staphylococcus species and subspecies to fleroxacin

11 July 2018

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Antimicrobial activity evaluations of two new quinolones, PD127391 (CI-960 and AM-1091) and PD131628.

11 July 2018

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Fleroxacin pharmacokinetics in aqueous and vitreous humors determined by using complete concentration-time data from individual rabbits

11 July 2018

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A randomized, double-blind study of the efficacy of fleroxacin versus trimethoprim-sulfamethoxazole in men with culture-proven chancroid

11 July 2018

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Fleroxacin clinical pharmacokinetics

11 July 2018

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Pharmacokinetics of 18F-labeled fleroxacin in rabbits with Escherichia coli infections, studied with positron emission tomography

11 July 2018

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In-vitro activity of fleroxacin

11 July 2018

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Penetration of fleroxacin into prostatic secretion and prostatic adenoma tissue

24 September 2018

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12 December 2020

In vitro activity of fleroxacin and 6 other antimicrobials against Acinetobacter anitratus

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12 December 2020

Performance characteristics of an eight-ring whole body PET scanner

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12 December 2020

Performance study of the PC-384 positron camera system for emission tomography of the brain

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12 December 2020

High-performance liquid chromatographic determination of 6,8-difluoro-1-(2-fluoroethyl)-1,4- dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid and its metabolites in laboratory animals

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12 December 2020

Susceptibility of 310 nonfermentative gram-negative bacteria to aztreonam, carumonam, ciprofloxacin, ofloxacin and fleroxacin

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12 December 2020

Liquid-chromatographic determination of fleroxacin in serum and urine

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12 December 2020

The penetration of fleroxacin into bronchial mucosa

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12 December 2020

Therapeutic effect of fleroxacin against experimental pneumonia in mice

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12 December 2020

Determination of the new fluoroquinolone fleroxacin and its N-demethyl and N-oxide metabolites in plasma and urine by high-performance liquid chromatography with fluorescence detection

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12 December 2020

An assessment of cerebral blood flow and metabolism after fleroxacin therapy

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12 December 2020

[A study on the treatment duration of an antibacterial agent in complicated urinary tract infections. Utility and recurrence after 14-day treatment by fleroxacin]

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12 December 2020

Synthesis and biodistribution of 18F-labeled fleroxacin

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12 December 2020

The average density of healthy lung

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12 December 2020

Clinical pharmacokinetics and tolerance of fleroxacin in healthy male volunteers

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12 December 2020

Pharmacokinetics and body fluid penetration of fleroxacin in healthy volunteers

1 reference

12 December 2020

Metabolism of fleroxacin in man

1 reference

12 December 2020

The metabolism and pharmacokinetics of fleroxacin in healthy subjects

1 reference

12 December 2020

Penetration of fleroxacin into maxillary sinus mucosa and palatine tonsil

1 reference

12 December 2020

Fleroxacin in the treatment of uncomplicated acute cystitis in women

1 reference

12 December 2020

Fleroxacin concentrations in myometrium, ovary and fallopian tube

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12 December 2020

Identifiers

DOI

10.1128/AAC.37.10.2144

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11 August 2017

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11 August 2017

PubMed publication ID

8257137

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