Heterologously-expressed and Liposome-reconstituted Human Transient Receptor Potential Melastatin 4 Channel (TRPM4) is a Functional Tetramer (Q35898155)

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scientific article published on 20 January 2016

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English	Heterologously-expressed and Liposome-reconstituted Human Transient Receptor Potential Melastatin 4 Channel (TRPM4) is a Functional Tetramer	scientific article published on 20 January 2016

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PMC publication ID

11 August 2017

Heterologously-expressed and Liposome-reconstituted Human Transient Receptor Potential Melastatin 4 Channel (TRPM4) is a Functional Tetramer (English)

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11 August 2017

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11 June 2020

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11 June 2020

Charles G. Cranfield

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11 June 2020

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Maryrose Constantine

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11 June 2020

Alex Macmillan

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11 June 2020

Robert M Graham

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20 January 2016

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Scientific Reports

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11 June 2020

19352

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11 June 2020

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20 January 2016

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Removal of the mechanoprotective influence of the cytoskeleton reveals PIEZO1 is gated by bilayer tension.

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Transient receptor potential melastatin-4 is involved in hypoxia-reoxygenation injury in the cardiomyocytes

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L596-W733 bond between the start of the S4-S5 linker and the TRP box stabilizes the closed state of TRPV4 channel

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Trpm4 gene invalidation leads to cardiac hypertrophy and electrophysiological alterations

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Detergent-free isolation, characterization, and functional reconstitution of a tetrameric K+ channel: the power of native nanodiscs

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Quality control in eukaryotic membrane protein overproduction

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Physiological functions of the TRPM4 channels via protein interactions

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TRPM4 channels couple purinergic receptor mechanoactivation and myogenic tone development in cerebral parenchymal arterioles

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TRPM4 channels in the cardiovascular system

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The TRPM4 channel inhibitor 9-phenanthrol

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TRPV1 structures in distinct conformations reveal activation mechanisms

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Structure of the TRPV1 ion channel determined by electron cryo-microscopy

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11 July 2018

9-Phenanthrol, a TRPM4 inhibitor, protects isolated rat hearts from ischemia-reperfusion injury

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11 July 2018

The ion channels to cytoskeleton connection as potential mechanism of mechanosensitivity.

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11 July 2018

TRPM4 channels in smooth muscle function

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11 July 2018

Mechanobiology in cardiac physiology and diseases

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11 July 2018

Molecular genetics and functional anomalies in a series of 248 Brugada cases with 11 mutations in the TRPM4 channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4726259

11 July 2018

TRPM4 channels in the cardiovascular system: physiology, pathophysiology, and pharmacology.

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11 July 2018

Ultrastructural freeze-fracture immunolabeling identifies plasma membrane-localized syndapin II as a crucial factor in shaping caveolae

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Differential effects of lipids and lyso-lipids on the mechanosensitivity of the mechanosensitive channels MscL and MscS.

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Cardioprotection from ischemia/reperfusion injury: basic and translational research

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11 July 2018

Piezo proteins are pore-forming subunits of mechanically activated channels

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11 July 2018

Structural biology of TRP channels.

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11 July 2018

Emerging concepts for the role of TRP channels in the cardiovascular system

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11 July 2018

A 3.5-nm structure of rat TRPV4 cation channel revealed by Zernike phase-contrast cryoelectron microscopy

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11 July 2018

Structure-functional intimacies of transient receptor potential channels

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11 July 2018

Impaired endocytosis of the ion channel TRPM4 is associated with human progressive familial heart block type I

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11 July 2018

Mechanosensitive channels in striated muscle and the cardiovascular system: not quite a stretch anymore.

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11 July 2018

Mechanosensitive TRP channels in cardiovascular pathophysiology

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Static light scattering to characterize membrane proteins in detergent solution

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Molecular basis of the mammalian pressure-sensitive ion channels: focus on vascular mechanotransduction

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Three-dimensional reconstruction using transmission electron microscopy reveals a swollen, bell-shaped structure of transient receptor potential melastatin type 2 cation channel.

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Membrane stretch-induced activation of a TRPM4-like nonselective cation channel in cerebral artery myocytes

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Gating of TRP channels: a voltage connection?

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The selectivity filter of the cation channel TRPM4.

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TRPM4 regulates calcium oscillations after T cell activation

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Decavanadate modulates gating of TRPM4 cation channels

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TRP channels as cellular sensors

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TRPM4 is a Ca2+-activated nonselective cation channel mediating cell membrane depolarization

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From worm to man: three subfamilies of TRP channels

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Gain-of-function mutations in TRPM4 cause autosomal dominant isolated cardiac conduction disease.

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24 September 2018

Phosphatidylinositol 4,5-bisphosphate rescues TRPM4 channels from desensitization.

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Erratum: Structure of the TRPA1 ion channel suggests regulatory mechanisms

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The non-selective cation-permeable channel TRPC3 is a tetrahedron with a cap on the large cytoplasmic end

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12 December 2020

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inferred from PubMed ID database lookup

The TRPM4 non-selective cation channel contributes to the mammalian atrial action potential

1 reference

https://pubmed.ncbi.nlm.nih.gov/26785754

12 December 2020

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10.1038/SREP19352

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11 June 2020

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