Developmental Patterning as a Quantitative Trait: Genetic Modulation of the Hoxb6 Mutant Skeletal Phenotype (Q35901753)

11 August 2017

Developmental Patterning as a Quantitative Trait: Genetic Modulation of the Hoxb6 Mutant Skeletal Phenotype (English)

1 reference

11 August 2017

1 reference

Claudia Kappen

1

1 reference

PMCID

4723086

11 August 2017

language of work or name

English

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publication date

22 January 2016

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11 August 2017

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11 August 2017

11

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11 August 2017

1

1 reference

11 August 2017

e0146019

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Creative Commons Attribution 4.0 International

11 August 2017

start time

22 January 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Hox genes control vertebrate body elongation by collinear Wnt repression

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Cdx and Hox genes differentially regulate posterior axial growth in mammalian embryos

11 July 2018

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Hox patterning of the vertebrate rib cage

11 July 2018

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The Genetics of a Difference in Skeletal Type between Two Inbred Strains of Mice (Balbc and C57blk).

11 July 2018

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Genetic and Non-Genetic Factors Which Influence the Type of the Skeleton in an Inbred Strain of Mice

11 July 2018

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Folate modulates Hox gene-controlled skeletal phenotypes.

11 July 2018

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Genetic and developmental basis of evolutionary pelvic reduction in threespine sticklebacks

11 July 2018

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Under cover: causes, effects and implications of Hsp90-mediated genetic capacitance

11 July 2018

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Genetic background modifies intestinal pseudo-obstruction and the expression of a reporter gene in Hox11L1-/- mice

11 July 2018

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Studies on the morphogenesis of the mouse sternum. III. Experiments on the closure and segmentation of the sternal bands

11 July 2018

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Congenital abnormalities of body patterning: embryology revisited

11 July 2018

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Hox10 and Hox11 genes are required to globally pattern the mammalian skeleton

11 July 2018

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Organizing axes in time and space; 25 years of colinear tinkering

11 July 2018

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A new view of patterning domains in the vertebrate mesoderm

11 July 2018

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Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning

11 July 2018

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From head to tail: links between the segmentation clock and antero-posterior patterning of the embryo

11 July 2018

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Hsp90 as a capacitor of phenotypic variation

11 July 2018

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RARgamma and Cdx1 interactions in vertebral patterning

11 July 2018

1 reference

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Evidence for medial/lateral specification and positional information within the presomitic mesoderm

11 July 2018

1 reference

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The HOX homeodomain proteins block CBP histone acetyltransferase activity

11 July 2018

1 reference

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Requirement for Pbx1 in skeletal patterning and programming chondrocyte proliferation and differentiation

11 July 2018

1 reference

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Localized and transient transcription of Hox genes suggests a link between patterning and the segmentation clock

11 July 2018

1 reference

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Patterning the embryonic axis: FGF signaling and how vertebrate embryos measure time.

11 July 2018

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Mice doubly deficient for the Polycomb Group genes Mel18 and Bmi1 reveal synergy and requirement for maintenance but not initiation of Hox gene expression

11 July 2018

1 reference

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Cell signaling switches HOX-PBX complexes from repressors to activators of transcription mediated by histone deacetylases and histone acetyltransferases.

11 July 2018

1 reference

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Modifier genes convert "simple" Mendelian disorders to complex traits

11 July 2018

1 reference

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Disruption of the homeobox gene Hoxb-6 in mice results in increased numbers of early erythrocyte progenitors

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

The paired homeobox gene Uncx4.1 specifies pedicles, transverse processes and proximal ribs of the vertebral column

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

Uncx4.1 is required for the formation of the pedicles and proximal ribs and acts upstream of Pax9

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

Embryology of the sternum.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

A genetic dissection of the retinoid signalling pathway in the mouse

11 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

11 July 2018

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0146019

Mammalian Trithorax and polycomb-group homologues are antagonistic regulators of homeotic development

21 January 2018

1 reference

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Pax1 and Pax9 synergistically regulate vertebral column development.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

Why do almost all mammals have seven cervical vertebrae? Developmental constraints, Hox genes, and cancer

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

Hsp90 as a capacitor for morphological evolution

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

Evidence for regulation of cartilage differentiation by the homeobox gene Hoxc-8.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

Hox genes and mammalian development.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

A model for extradenticle function as a switch that changes HOX proteins from repressors to activators

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

Function of homeobox genes in skeletal development

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

Whole-mount in situ hybridization in the mouse embryo: gene expression in three dimensions

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

The role of Pax-1 in axial skeleton development.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

Axial homeosis and appendicular skeleton defects in mice with a targeted disruption of hoxd-11

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

Targeted disruptions of the murine Hoxa-4 and Hoxa-6 genes result in homeotic transformations of components of the vertebral column

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

Genetic interaction between hoxb-5 and hoxb-6 is revealed by nonallelic noncomplementation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

Axial abnormalities following disturbed growth in mitomycin C-treated mouse embryos.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

Developmental stability in the mouse vertebral column

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

11 July 2018

Vertebral malformations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

The Hox-2 homeo box gene complex on mouse chromosome 11 is closely linked to Re

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

Periodic segmental anomalies induced by heat shock in the chick embryo are associated with the cell cycle.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

The inheritance of vertebral shape in the mouse. I. A study using Fourier analysis to examine patterns of inheritance in the morphology of cervical and upper thoracic vertebrae

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

Determination of epithelial half-somites in skeletal morphogenesis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

Collinear activation of Hoxb genes during gastrulation is linked to mesoderm cell ingression.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

Hox genes specify vertebral types in the presomitic mesoderm

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

Ventral axial organs regulate expression of myotomal Fgf-8 that influences rib development

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

Genetic modifiers of otocephalic phenotypes in Otx2 heterozygous mutant mice.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

Embryonic retinoic acid synthesis is required for forelimb growth and anteroposterior patterning in the mouse

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

Inductive signals from the somatopleure mediated by bone morphogenetic proteins are essential for the formation of the sternal component of avian ribs.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

Mapping of a major genetic modifier of embryonic lethality in TGF beta 1 knockout mice.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4723086

Why do almost all mammals have seven cervical vertebrae? Developmental constraints,Hox genes, and cancer

24 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0146019

Erratum: Positional cloning of a global regulator of anterior–posterior patterning in mice

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0146019

[Radiographically demonstrable spinal changes in asymptomatic young men]

21 January 2018

1 reference

12 December 2020

Homeotic transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid

1 reference

12 December 2020

Genetical studies on the skeleton of the mouse. I. Minor variations of the vertebral column

1 reference

12 December 2020

Hoxb-4 (Hox-2.6) mutant mice show homeotic transformation of a cervical vertebra and defects in the closure of the sternal rudiments

1 reference

12 December 2020

Strain dependency of TGFbeta1 function during embryogenesis

1 reference

12 December 2020

Genetical studies on the skeleton of the mouse. III. Skeletal variation in wild populations

1 reference

12 December 2020

Hox genes and morphological identity: axial versus lateral patterning in the vertebrate mesoderm

1 reference

12 December 2020

Keep your eyes on the ribs: the spectrum of normal variants and diseases that involve the ribs

1 reference

12 December 2020

Temporal colinearity and the phylotypic progression: a basis for the stability of a vertebrate Bauplan and the evolution of morphologies through heterochrony

1 reference

12 December 2020

Mediolateral somitic origin of ribs and dermis determined by quail-chick chimeras

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0146019

Identifiers

DOI

1 reference

11 August 2017

0 references

1 reference

11 August 2017

1 reference

PMCID

4723086