Intrinsic signaling function of APP as a novel target of three V642 mutations linked to familial Alzheimer's disease. (Q35904068)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8670881%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

title

Intrinsic signaling function of APP as a novel target of three V642 mutations linked to familial Alzheimer's disease (English)

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16 October 2019

0 references

Okamoto T

1

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16 October 2019

Takeda S

2

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16 October 2019

Giambarella U

3

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Murayama Y

4

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Matsui T

5

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Katada T

6

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Matsuura Y

7

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16 October 2019

Nishimoto I

8

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16 October 2019

language of work or name

English

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publication date

1 August 1996

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16 October 2019

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16 October 2019

volume

15

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16 October 2019

issue

15

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16 October 2019

page(s)

3769-3777

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Negative transactivation of cAMP response element by familial Alzheimer's mutants of APP.

16 October 2019

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The regions of the Fe65 protein homologous to the phosphotyrosine interaction/phosphotyrosine binding domain of Shc bind the intracellular domain of the Alzheimer's amyloid precursor protein

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27 July 2018

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27 July 2018

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Peptides containing the RERMS sequence of amyloid beta/A4 protein precursor bind cell surface and promote neurite extension

27 July 2018

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CREB: a mediator of long-term memory from mollusks to mammals

27 July 2018

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Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the beta 2-adrenoceptor

27 July 2018

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Downregulation of amyloid precursor protein inhibits neurite outgrowth in vitro

27 July 2018

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Ligand-dependent G protein coupling function of amyloid transmembrane precursor

27 July 2018

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Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

27 July 2018

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beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity

27 July 2018

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A constitutively activating mutation of the luteinizing hormone receptor in familial male precocious puberty

27 July 2018

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GAP-43 augments G protein-coupled receptor transduction in Xenopus laevis oocytes.

27 July 2018

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Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

27 July 2018

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Direct control of exocytosis by receptor-mediated activation of the heterotrimeric GTPases Gi and G(o) or by the expression of their active G alpha subunits

27 July 2018

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Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

27 July 2018

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Activation of a G protein complex by aggregation of beta-1,4-galactosyltransferase on the surface of sperm

27 July 2018

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Signalling downstream of activated mammalian Notch

27 July 2018

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Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene

27 July 2018

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Two guanine nucleotide-binding proteins in rat brain serving as the specific substrate of islet-activating protein, pertussis toxin. Interaction of the alpha-subunits with beta gamma-subunits in development of their biological activities.

27 July 2018

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Expression of the Alzheimer amyloid precursor gene transcripts in the human brain.

27 July 2018

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The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

27 July 2018

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27 July 2018

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Oncogenic activation of p185neu stimulates tyrosine phosphorylation in vivo

27 July 2018

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27 July 2018

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Early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene

27 July 2018

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A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease

27 July 2018

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The 717Val----Ile substitution in amyloid precursor protein is associated with familial Alzheimer's disease regardless of ethnic groups

27 July 2018

1 reference

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Isolation of baculovirus-derived secreted and full-length beta-amyloid precursor protein

27 July 2018

1 reference

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An intracellular guanine nucleotide release protein for G0. GAP-43 stimulates isolated alpha subunits by a novel mechanism

27 July 2018

1 reference

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Localization of Alzheimer beta A4 amyloid precursor protein at central and peripheral synaptic sites.

27 July 2018

1 reference

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Morphoregulatory activities of NCAM and N-cadherin can be accounted for by G protein-dependent activation of L- and N-type neuronal Ca2+ channels

27 July 2018

1 reference

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Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

27 July 2018

1 reference

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Beta amyloid precursor protein mediates neuronal cell-cell and cell-surface adhesion

27 July 2018

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The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth

27 July 2018

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Role of amyloid precursor protein (APP): study with antisense transfection of human neuroblastoma cells

27 July 2018

1 reference

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Molecular and prospective phenotypic characterization of a pedigree with familial Alzheimer's disease and a missense mutation in codon 717 of the beta-amyloid precursor protein gene

27 July 2018

1 reference

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Constitutive activation of the alpha 1B-adrenergic receptor by all amino acid substitutions at a single site. Evidence for a region which constrains receptor activation

27 July 2018

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Degeneration in vitro of post-mitotic neurons overexpressing the Alzheimer amyloid protein precursor

27 July 2018

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Intraneuronal compartments of the amyloid precursor protein.

27 July 2018

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Participation of the protein Go in multiple aspects of behavior in C. elegans

24 September 2018

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Modulation of serotonin-controlled behaviors by Go in Caenorhabditis elegans

24 September 2018

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Neural cell adhesion molecules influence second messenger systems

24 September 2018

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G0 is a major growth cone protein subject to regulation by GAP-43.

24 September 2018

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Mis-sense mutation Val&rarr;Ile in exon 17 of amyloid precursor protein gene in Japanese familial Alzheimer's disease

24 September 2018

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In vivo coupling of insulin-like growth factor II/mannose 6-phosphate receptor to heteromeric G proteins. Distinct roles of cytoplasmic domains and signal sequestration by the receptor

24 September 2018

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12 December 2020

Pertussis toxin suppresses long-term potentiation of hippocampal mossy fiber synapses

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A pertussis toxin-sensitive G protein in hippocampal long-term potentiation

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12 December 2020

Detection of G protein-activator regions in M4 subtype muscarinic, cholinergic, and alpha 2-adrenergic receptors based upon characteristics in primary structure

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12 December 2020

A simple structure encodes G protein-activating function of the IGF-II/mannose 6-phosphate receptor

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12 December 2020

10.1002/J.1460-2075.1996.TB00750.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8670881%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8670881%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

PubMed publication ID

8670881

1 reference