Interdependent and independent roles of type I interferons and IL-6 in innate immune, neuroinflammatory and sickness behaviour responses to systemic poly I:C. (Q35905501)

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scientific article published on 18 April 2015

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English	Interdependent and independent roles of type I interferons and IL-6 in innate immune, neuroinflammatory and sickness behaviour responses to systemic poly I:C.	scientific article published on 18 April 2015

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scholarly article

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6 March 2020

Interdependent and independent roles of type I interferons and IL-6 in innate immune, neuroinflammatory and sickness behaviour responses to systemic poly I:C (English)

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6 March 2020

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Nigel J Stevenson

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Colm Cunningham

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6 March 2020

author name string

Carol Murray

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Éadaoin W Griffin

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Elaine O'Loughlin

3

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Aoife Lyons

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Suaad Ahmed

6

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Andrew Harkin

8

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publication date

18 April 2015

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Brain, Behavior, and Immunity

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48

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274-286

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Interferons in the central nervous system: a few instruments play many tunes.

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Systemic challenge with the TLR3 agonist poly I:C induces amplified IFNalpha/beta and IL-1beta responses in the diseased brain and exacerbates chronic neurodegeneration

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Interferon type I receptor-deficient mice have altered disease symptoms in response to influenza virus

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Signal integration between IFNgamma and TLR signalling pathways in macrophages

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Sleep and body temperature responses in an acute viral infection model are altered in interferon type I receptor-deficient mice

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Neuropsychiatric adverse effects of interferon-alpha: recognition and management

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The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

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The viral mimic, polyinosinic:polycytidylic acid, induces fever in rats via an interleukin-1-dependent mechanism.

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Interferon-producing cells: on the front line in immune responses against pathogens

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Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

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Cross talk of the interferon-alpha/beta signalling complex with gp130 for effective interleukin-6 signalling

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A weak signal for strong responses: interferon-alpha/beta revisited

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IRF family of transcription factors as regulators of host defense

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Acute interferon-alpha administration modulates sucrose consumption in the rat.

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Analysis of transcription factors regulating induction of indoleamine 2,3-dioxygenase by IFN-gamma

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24 September 2018

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24 September 2018

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The reduction of voluntary physical activity after poly I:C injection is independent of the effect of poly I:C-induced interferon-beta in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/25900439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of interleukin-6 by interferon alfa and its abrogation by a serine protease inhibitor in patients with chronic hepatitis C

1 reference

https://pubmed.ncbi.nlm.nih.gov/25900439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.BBI.2015.04.009

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Europe PubMed Central

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6 March 2020

1 reference

Europe PubMed Central

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6 March 2020

1 reference

Europe PubMed Central

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6 March 2020

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