T7 RNA polymerase transcription complex: what you see is not what you get. (Q35907935)

11 August 2017

T7 RNA polymerase transcription complex: what you see is not what you get. (English)

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11 August 2017

K Severinov

1

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PMC publication ID

33347

11 August 2017

language of work or name

English

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publication date

1 January 2001

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Proceedings of the National Academy of Sciences of the United States of America

11 August 2017

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11 August 2017

98

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11 August 2017

1

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11 August 2017

5-7

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The specificity loop of T7 RNA polymerase interacts first with the promoter and then with the elongating transcript, suggesting a mechanism for promoter clearance

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33347

Studies of promoter recognition and start site selection by T7 RNA polymerase using a comprehensive collection of promoter variants

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33347

A structural model of transcription elongation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33347

Architecture of RNA polymerase II and implications for the transcription mechanism

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33347

Structure of a transcribing T7 RNA polymerase initiation complex

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33347

Crystal structure of Thermus aquaticus core RNA polymerase at 3.3 A resolution.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33347

Structural basis for initiation of transcription from an RNA polymerase-promoter complex

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33347

Transcription elongation: structural basis and mechanisms

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33347

Characterization of an unusual, sequence-specific termination signal for T7 RNA polymerase

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33347

Basic mechanisms of transcript elongation and its regulation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33347

The phage RNA polymerases are related to DNA polymerases and reverse transcriptases

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33347

Processivity in early stages of transcription by T7 RNA polymerase

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33347

The 9S RNA precursor of Escherichia coli 5S RNA has three structural domains: implications for processing

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33347

A thermodynamic analysis of RNA transcript elongation and termination in Escherichia coli

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33347

Substitution of a single bacteriophage T3 residue in bacteriophage T7 RNA polymerase at position 748 results in a switch in promoter specificity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33347

The RNA-DNA hybrid maintains the register of transcription by preventing backtracking of RNA polymerase.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33347

A mutant RNA polymerase reveals a kinetic mechanisms for the switch between nonproductive stuttering synthesis and productive initiation during promoter clearance.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33347

Regulation of pyrBI operon expression in Escherichia coli by UTP-sensitive reiterative RNA synthesis during transcriptional initiation.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33347

Mechanistic model of the elongation complex of Escherichia coli RNA polymerase

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33347

Genetic dissection of the transcription cycle. A mutant RNA polymerase that cannot hold onto a promoter

24 September 2018

1 reference

12 December 2020

Characterization of two types of termination signal for bacteriophage T7 RNA polymerase

1 reference

12 December 2020

Localization of a sigma70 binding site on the N terminus of the Escherichia coli RNA polymerase beta' subunit

1 reference

12 December 2020

The 8-nucleotide-long RNA:DNA hybrid is a primary stability determinant of the RNA polymerase II elongation complex

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.021535298

1 reference

11 August 2017

1 reference

PMC publication ID

33347

11 August 2017

PubMed publication ID

11120893

1 reference

PMC publication ID

33347