Characterization of a gene cluster responsible for the biosynthesis of anticancer agent FK228 in Chromobacterium violaceum No. 968 (Q35913058)

11 August 2017

Characterization of a gene cluster responsible for the biosynthesis of anticancer agent FK228 in Chromobacterium violaceum No. 968 (English)

1 reference

Chromobacterium violaceum

11 August 2017

2 references

1 reference

Yi-Qiang Cheng

1

1 reference

11 August 2017

Min Yang

series ordinal

2

1 reference

11 August 2017

Andrea M Matter

series ordinal

3

1 reference

11 August 2017

language of work or name

English

0 references

publication date

30 March 2007

1 reference

full work available at URL

11 August 2017

https://europepmc.org/articles/pmc1932697?pdf=render

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1128/aem.01751-06?email=unpaywall_01@example.com

published in

Applied and Environmental Microbiology

1 reference

11 August 2017

73

1 reference

11 August 2017

11

1 reference

11 August 2017

3460-3469

1 reference

https://api.unpaywall.org/v2/10.1128/aem.01751-06?email=unpaywall_01@example.com

11 August 2017

1 reference

19 March 2024

access restriction status

open access

1 reference

inferred from online access status

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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P21-dependent g(1)arrest with downregulation of cyclin D1 and upregulation of cyclin E by the histone deacetylase inhibitor FR901228

11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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FR901228, a potent antitumor antibiotic, is a novel histone deacetylase inhibitor.

11 July 2018

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FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. II. Structure determination

11 July 2018

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Action of FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum no. 968, on Ha-ras transformed NIH3T3 cells

11 July 2018

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FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties, and antitumor activity

11 July 2018

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Second symbiotic megaplasmid in Rhizobium meliloti carrying exopolysaccharide and thiamine synthesis genes

11 July 2018

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11 July 2018

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A highly specific D-hydroxyisovalerate dehydrogenase from the enniatin producer Fusarium sambucinum

11 July 2018

1 reference

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Analysis of Streptomyces avermitilis genes required for avermectin biosynthesis utilizing a novel integration vector

11 July 2018

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Deciphering the biosynthetic codes for the potent anti-SARS-CoV cyclodepsipeptide valinomycin in Streptomyces tsusimaensis ATCC 15141.

11 July 2018

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Identification of thiols and glutathione conjugates of depsipeptide FK228 (FR901228), a novel histone protein deacetylase inhibitor, in the blood

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932697

A genomics-guided approach for discovering and expressing cryptic metabolic pathways.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932697

FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932697

Inhibitor of histone deacetylation, depsipeptide (FR901228), in the treatment of peripheral and cutaneous T-cell lymphoma: a case report

24 September 2018

1 reference

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Role of type II thioesterases: evidence for removal of short acyl chains produced by aberrant decarboxylation of chain extender units

24 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932697

Depsipeptide (FR901228): a novel therapeutic agent with selective, in vitro activity against human B-cell chronic lymphocytic leukemia cells.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932697

Effects of a novel antitumor depsipeptide, FR901228, on human breast cancer cells.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932697

Predictive, structure-based model of amino acid recognition by nonribosomal peptide synthetase adenylation domains

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1932697

FR901228 causes mitotic arrest but does not alter microtubule polymerization

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17400765

12 December 2020

inferred from PubMed ID database lookup

Characterization of the cereulide NRPS alpha-hydroxy acid specifying modules: activation of alpha-keto acids and chiral reduction on the assembly line

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17400765

12 December 2020

inferred from PubMed ID database lookup

HDAC inhibitors overcome first hurdle

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17400765

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1128/AEM.01751-06

1 reference

11 August 2017

1 reference

11 August 2017

PubMed publication ID

17400765

1 reference