Evidence for a primary islet autoantigen (preproinsulin 1) for insulitis and diabetes in the nonobese diabetic mouse (Q35918236)

11 August 2017

Evidence for a primary islet autoantigen (preproinsulin 1) for insulitis and diabetes in the nonobese diabetic mouse (English)

1 reference

11 August 2017

1 reference

11

George S Eisenbarth

1 reference

11 August 2017

Hiroaki Moriyama

1

1 reference

11 August 2017

Norio Abiru

2

1 reference

11 August 2017

Johanna Paronen

3

1 reference

11 August 2017

Kamila Sikora

4

1 reference

11 August 2017

Edwin Liu

5

1 reference

11 August 2017

Dongmei Miao

6

1 reference

11 August 2017

Devasenan Devendra

7

1 reference

11 August 2017

Joshua Beilke

8

1 reference

11 August 2017

Roberto Gianani

9

1 reference

11 August 2017

Ron G Gill

10

1 reference

11 August 2017

language of work or name

English

0 references

publication date

18 August 2003

1 reference

Proceedings of the National Academy of Sciences of the United States of America

11 August 2017

1 reference

11 August 2017

100

1 reference

11 August 2017

18

1 reference

11 August 2017

10376-10381

1 reference

Acceleration of type 1 diabetes mellitus in proinsulin 2-deficient NOD mice

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193569

Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193569

Projection of an immunological self shadow within the thymus by the aire protein

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193569

T cell response to preproinsulin I and II in the nonobese diabetic mouse

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193569

Cblb is a major susceptibility gene for rat type 1 diabetes mellitus

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193569

Lymphopenia in the BB rat model of type 1 diabetes is due to a mutation in a novel immune-associated nucleotide (Ian)-related gene

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193569

Induction and acceleration of insulitis/diabetes in mice with a viral mimic (polyinosinic-polycytidylic acid) and an insulin self-peptide

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193569

Genetic protection from the inflammatory disease type 1 diabetes in humans and animal models

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193569

Does GAD have a unique role in triggering IDDM?

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193569

Has GAD a central role in type 1 diabetes?

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193569

Induction of diabetes in nonobese diabetic mice by Th2 T cell clones from a TCR transgenic mouse

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193569

Early expression of antiinsulin autoantibodies of humans and the NOD mouse: evidence for early determination of subsequent diabetes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193569

The role of CD4 vs. CD8 T cells in IDDM.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193569

Transgenes and knockout mutations in animal models of type 1 diabetes and multiple sclerosis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193569

Widespread expression of an autoantigen-GAD65 transgene does not tolerize non-obese diabetic mice and can exacerbate disease

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193569

Role of viruses in type I diabetes.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193569

The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193569

Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193569

A role of Hsp60 in autoimmune diabetes: analysis in a transgenic model.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193569

Differential expression of the two nonallelic proinsulin genes in the developing mouse embryo

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193569

Defining criteria for autoimmune diseases (Witebsky's postulates revisited)

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193569

Insulin-specific T cells are a predominant component of islet infiltrates in pre-diabetic NOD mice

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193569

The NOD mouse: recessive diabetogenic gene in the major histocompatibility complex

11 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1834450100

Millennium award recipient contribution. Identification of children with early onset and high incidence of anti-islet autoantibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1834450100

Peripheral-antigen-expressing cells in thymic medulla: factors in self-tolerance and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1834450100

Progression of autoimmune diabetes driven by avidity maturation of a T-cell population

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1834450100

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1834450100

A Molecular Basis for MHC Class II—Associated Autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1834450100

Polygenic nature of spontaneous diabetes in the rat. Permissive MHC haplotype and presence of the lymphopenic trait of the BB rat are not sufficient to produce susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1834450100

Transgenic expression of mouse proinsulin II prevents diabetes in nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1834450100

Intrathymic expression of genes involved in organ specific autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1834450100

Insulin expression levels in the thymus modulate insulin-specific autoreactive T-cell tolerance: the mechanism by which the IDDM2 locus may predispose to diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1834450100

Acceleration of type 1 diabetes mellitus in proinsulin 2–deficient NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1834450100

Anti-LFA-1 therapy induces long-term islet allograft acceptance in the absence of IFN-gamma or IL-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1834450100

Peptide and major histocompatibility complex-specific breaking of humoral tolerance to native insulin with the B9-23 peptide in diabetes-prone and normal mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1834450100

Dual overlapping peptides recognized by insulin peptide B:9-23 T cell receptor AV13S3 T cell clones of the NOD mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1834450100

Closing in on type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1834450100

Establishing insulin 1 and insulin 2 knockout congenic strains on NOD genetic background

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12925730

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Pancreatic hormone expression in the murine thymus: localization in dendritic cells and macrophages

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12925730

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Insulin autoantibodies are associated with islet inflammation but not always related to diabetes progression in NOD congenic mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12925730

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1834450100

1 reference

11 August 2017

0 references

1 reference

11 August 2017

1 reference