Hepatic regulation of apolipoprotein B. (Q35919242)

11 August 2017

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title

Hepatic regulation of apolipoprotein B. (English)

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11 August 2017

Rita Kohen Avramoglu

1

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11 August 2017

Khosrow Adeli

series ordinal

2

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11 August 2017

publication date

1 December 2004

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Reviews in Endocrine and Metabolic Disorders

11 August 2017

published in

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11 August 2017

volume

5

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11 August 2017

issue

4

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11 August 2017

page(s)

293-301

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Endoplasmic reticulum localization of the low density lipoprotein receptor mediates presecretory degradation of apolipoprotein B

11 August 2017

cites work

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12 December 2020

The Low Density Lipoprotein Receptor Prevents Secretion of Dense ApoB100-containing Lipoproteins from the Liver

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12 December 2020

Hepatic expression of microsomal triglyceride transfer protein and in vivo secretion of triglyceride-rich lipoproteins are increased in obese diabetic mice

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12 December 2020

Sterol regulatory element-binding protein negatively regulates microsomal triglyceride transfer protein gene transcription

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12 December 2020

Regulation of microsomal triglyceride transfer protein gene by insulin in HepG2 cells: roles of MAPKerk and MAPKp38.

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12 December 2020

Apolipoprotein B is intracellularly associated with an ER-60 protease homologue in HepG2 cells

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12 December 2020

Nascent lipidated apolipoprotein B is transported to the Golgi as an incompletely folded intermediate as probed by its association with network of endoplasmic reticulum molecular chaperones, GRP94, ERp72, BiP, calreticulin, and cyclophilin B

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12 December 2020

The role of the LDL receptor in apolipoprotein B secretion

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12 December 2020

Apoprotein B100 has a prolonged interaction with the translocon during which its lipidation and translocation change from dependence on the microsomal triglyceride transfer protein to independence.

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12 December 2020

Intracellular degradation of newly synthesized apolipoprotein B.

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12 December 2020

Hepatic PTP-1B expression regulates the assembly and secretion of apolipoprotein B-containing lipoproteins: evidence from protein tyrosine phosphatase-1B overexpression, knockout, and RNAi studies

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12 December 2020

Co-translational interactions of apoprotein B with the ribosome and translocon during lipoprotein assembly or targeting to the proteasome

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12 December 2020

The microsomal triglyceride transfer protein catalyzes the post-translational assembly of apolipoprotein B-100 very low density lipoprotein in McA-RH7777 cells

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12 December 2020

The assembly and secretion of apolipoprotein B-containing lipoproteins

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12 December 2020

Overexpression of the tumor autocrine motility factor receptor Gp78, a ubiquitin protein ligase, results in increased ubiquitinylation and decreased secretion of apolipoprotein B100 in HepG2 cells

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12 December 2020

Microsomal membrane-associated apoB is the direct precursor of secreted VLDL in primary cultures of rat hepatocytes

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12 December 2020

Lipid peroxidation and oxidant stress regulate hepatic apolipoprotein B degradation and VLDL production

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12 December 2020

Microsomal triglyceride transfer protein (MTP) regulation in HepG2 cells: insulin negatively regulates MTP gene expression

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12 December 2020

Intracellular assembly of very low density lipoproteins containing apolipoprotein B100 in rat hepatoma McA-RH7777 cells

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12 December 2020

Calnexin and other factors that alter translocation affect the rapid binding of ubiquitin to apoB in the Sec61 complex

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12 December 2020

Apoprotein B100, an inefficiently translocated secretory protein, is bound to the cytosolic chaperone, heat shock protein 70

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12 December 2020

Blocking microsomal triglyceride transfer protein interferes with apoB secretion without causing retention or stress in the ER.

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12 December 2020

Apoprotein B degradation is promoted by the molecular chaperones hsp90 and hsp70.

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12 December 2020

The N-linked oligosaccharides at the amino terminus of human apoB are important for the assembly and secretion of VLDL.

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12 December 2020

Circumstances and mechanisms of inhibition of translation by secondary structure in eucaryotic mRNAs

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12 December 2020

Post-transcriptional gene regulatory mechanisms in eukaryotes: an overview

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12 December 2020

Mechanisms of hepatic very low-density lipoprotein overproduction in insulin resistance

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12 December 2020

Substrate delivery as a determinant of hepatic apoB secretion

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12 December 2020

Hepatic very low density lipoprotein-ApoB overproduction is associated with attenuated hepatic insulin signaling and overexpression of protein-tyrosine phosphatase 1B in a fructose-fed hamster model of insulin resistance

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12 December 2020

Complete cDNA and derived protein sequence of human apolipoprotein B-100.

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12 December 2020

Inhibition of Net HepG2 Cell Apolipoprotein B Secretion by the Citrus Flavonoid Naringenin Involves Activation of Phosphatidylinositol 3-Kinase, Independent of Insulin Receptor Substrate-1 Phosphorylation

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12 December 2020

Transcriptional regulation of human and hamster microsomal triglyceride transfer protein genes. Cell type-specific expression and response to metabolic regulators

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12 December 2020

Normal activity of microsomal triglyceride transfer protein is required for the oleate-induced secretion of very low density lipoproteins containing apolipoprotein B from McA-RH7777 cells

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12 December 2020

Tunicamycin induces ubiquitination and degradation of apolipoprotein B in HepG2 cells

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12 December 2020

The conversion of apoB100 low density lipoprotein/high density lipoprotein particles to apoB100 very low density lipoproteins in response to oleic acid occurs in the endoplasmic reticulum and not in the Golgi in McA RH7777 cells

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12 December 2020

Complexity in the secretory pathway: the assembly and secretion of apolipoprotein B-containing lipoproteins

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12 December 2020

Increased production of apolipoprotein B-containing lipoproteins in the absence of hyperlipidemia in transgenic mice expressing cholesterol 7alpha-hydroxylase

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12 December 2020

Cotranslocational insertion of apolipoprotein B into the inner leaflet of the endoplasmic reticulum

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12 December 2020

Impaired hepatic apolipoprotein B and E translation in streptozotocin diabetic rats

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12 December 2020

Thyroid hormone modulates apolipoprotein B gene expression in HepG2 cells

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12 December 2020

Translational control of apolipoprotein B mRNA: regulation via cis elements in the 5' and 3' untranslated regions

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12 December 2020

Insulin modulation of hepatic synthesis and secretion of apolipoprotein B by rat hepatocytes

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12 December 2020

Mechanisms of hepatic very low density lipoprotein overproduction in insulin resistance. Evidence for enhanced lipoprotein assembly, reduced intracellular ApoB degradation, and increased microsomal triglyceride transfer protein in a fructose-fed ham

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12 December 2020

Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

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12 December 2020

Interaction of newly synthesized apolipoprotein B with calnexin and calreticulin requires glucose trimming in the endoplasmic reticulum.

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12 December 2020

Overexpression of the endoplasmic reticulum 60 protein ER-60 downregulates apoB100 secretion by inducing its intracellular degradation via a nonproteasomal pathway: evidence for an ER-60-mediated and pCMB-sensitive intracellular degradative pathway

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12 December 2020

The late addition of core lipids to nascent apolipoprotein B100, resulting in the assembly and secretion of triglyceride-rich lipoproteins, is independent of both microsomal triglyceride transfer protein activity and new triglyceride synthesis

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12 December 2020

Progress towards understanding the role of microsomal triglyceride transfer protein in apolipoprotein-B lipoprotein assembly

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12 December 2020

Amino acid sequences within the beta1 domain of human apolipoprotein B can mediate rapid intracellular degradation

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12 December 2020

Synthesis and secretion of hepatic apolipoprotein B-containing lipoproteins.

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12 December 2020

Enhanced expression of hepatic acyl-coenzyme A synthetase and microsomal triglyceride transfer protein messenger RNAs in the obese and hypertriglyceridemic rat with visceral fat accumulation.

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12 December 2020

Efficient glycosylation site utilization by intracellular apolipoprotein B. Implications for proteasomal degradation

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12 December 2020

Inhibition of the microsomal triglyceride transfer protein blocks the first step of apolipoprotein B lipoprotein assembly but not the addition of bulk core lipids in the second step

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12 December 2020

Transmembrane lipid transfer is crucial for providing neutral lipids during very low density lipoprotein assembly in endoplasmic reticulum

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12 December 2020

Secretion of apolipoprotein B-containing lipoproteins from HeLa cells is dependent on expression of the microsomal triglyceride transfer protein and is regulated by lipid availability

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12 December 2020

A proteomic approach identifies proteins in hepatocytes that bind nascent apolipoprotein B.

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12 December 2020

The triple threat to nascent apolipoprotein B. Evidence for multiple, distinct degradative pathways

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12 December 2020

Expression of carboxyl-terminally truncated forms of human apolipoprotein B in rat hepatoma cells. Evidence that the length of apolipoprotein B has a major effect on the buoyant density of the secreted lipoproteins.

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12 December 2020

Insulin-mediated inhibition of apolipoprotein B secretion requires an intracellular trafficking event and phosphatidylinositol 3-kinase activation: studies with brefeldin A and wortmannin in primary cultures of rat hepatocytes

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12 December 2020

Ferritins can regulate the secretion of apolipoprotein B.

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12 December 2020

10.1023/B:REMD.0000045100.66675.92

Identifiers

DOI

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Dimensions Publication ID

11 August 2017

1013494801

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