Anticancer drug oxaliplatin induces acute cooling-aggravated neuropathy via sodium channel subtype Na(V)1.6-resurgent and persistent current (Q35921901)

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scientific article published on 9 April 2012

Language	Label	Description	Also known as
English	Anticancer drug oxaliplatin induces acute cooling-aggravated neuropathy via sodium channel subtype Na(V)1.6-resurgent and persistent current	scientific article published on 9 April 2012

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scholarly article

1 reference

Europe PubMed Central

11 August 2017

Anticancer drug oxaliplatin induces acute cooling-aggravated neuropathy via sodium channel subtype Na(V)1.6-resurgent and persistent current (English)

1 reference

Europe PubMed Central

11 August 2017

1 reference

based on heuristic

inferred from title

Christian Alzheimer

7

object named as

Christian Alzheimer

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Europe PubMed Central

11 August 2017

author name string

Ruth Sittl

1

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Europe PubMed Central

11 August 2017

Angelika Lampert

2

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Europe PubMed Central

11 August 2017

Tobias Huth

3

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Europe PubMed Central

11 August 2017

E Theresa Schuy

4

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Europe PubMed Central

11 August 2017

Andrea S Link

5

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Europe PubMed Central

11 August 2017

Johannes Fleckenstein

6

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Europe PubMed Central

11 August 2017

Peter Grafe

8

1 reference

Europe PubMed Central

11 August 2017

Richard W Carr

9

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Europe PubMed Central

11 August 2017

language of work or name

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publication date

9 April 2012

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Europe PubMed Central

11 August 2017

Proceedings of the National Academy of Sciences of the United States of America

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Europe PubMed Central

11 August 2017

109

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Europe PubMed Central

11 August 2017

17

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Europe PubMed Central

11 August 2017

6704-6709

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Europe PubMed Central

11 August 2017

μ-Conotoxins that differentially block sodium channels NaV1.1 through 1.8 identify those responsible for action potentials in sciatic nerve

1 reference

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2 October 2017

Detecting acute neurotoxicity during platinum chemotherapy by neurophysiological assessment of motor nerve hyperexcitability.

1 reference

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2 October 2017

Control of transient, resurgent, and persistent current by open-channel block by Na channel beta4 in cultured cerebellar granule neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

2 October 2017

Self-reported cold sensitivity in normal subjects and in patients with traumatic hand injuries or hand-arm vibration syndrome

1 reference

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2 October 2017

Inwardly permeating Na ions generate the voltage dependence of resurgent Na current in cerebellar Purkinje neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

2 October 2017

Regulation of persistent Na current by interactions between beta subunits of voltage-gated Na channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

2 October 2017

Non-proteolytic effect of beta-site APP-cleaving enzyme 1 (BACE1) on sodium channel function

1 reference

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2 October 2017

Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy

1 reference

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2 October 2017

Multiple sodium channels and their roles in electrogenesis within dorsal root ganglion neurons

1 reference

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SCN9A mutations in paroxysmal extreme pain disorder: allelic variants underlie distinct channel defects and phenotypes

1 reference

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2 October 2017

Impaired inactivation gate stabilization predicts increased persistent current for an epilepsy-associated SCN1A mutation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

2 October 2017

Subtype specificity of scorpion beta-toxin Tz1 interaction with voltage-gated sodium channels is determined by the pore loop of domain 3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

2 October 2017

Oxaliplatin induces hyperexcitability at motor and autonomic neuromuscular junctions through effects on voltage-gated sodium channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

2 October 2017

Production of resurgent current in NaV1.6-null Purkinje neurons by slowing sodium channel inactivation with beta-pompilidotoxin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

2 October 2017

Sodium channel beta4, a new disulfide-linked auxiliary subunit with similarity to beta2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

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Phenotype and function of somatic primary afferent nociceptive neurones with C-, Adelta- or Aalpha/beta-fibres

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

2 October 2017

Compact myelin dictates the differential targeting of two sodium channel isoforms in the same axon.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

2 October 2017

Sodium channel Na(v)1.6 is localized at nodes of ranvier, dendrites, and synapses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

2 October 2017

Electrophysiological characterization of SCN5A mutations causing long QT (E1784K) and Brugada (R1512W and R1432G) syndromes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

2 October 2017

Long-term follow-up evaluation of cold sensitivity following nerve injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

2 October 2017

Mutations in an S4 segment of the adult skeletal muscle sodium channel cause paramyotonia congenita

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

2 October 2017

Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

11 July 2018

Oxaliplatin-induced cold hypersensitivity is due to remodelling of ion channel expression in nociceptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

11 July 2018

Human voltage-gated sodium channel mutations that cause inherited neuronal and muscle channelopathies increase resurgent sodium currents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

11 July 2018

Threshold tracking techniques in the study of human peripheral nerve

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

11 July 2018

Altered subthreshold sodium currents and disrupted firing patterns in Purkinje neurons of Scn8a mutant mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

11 July 2018

The NEURON simulation environment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

11 July 2018

β-Site APP-cleaving enzyme 1 (BACE1) cleaves cerebellar Na+ channel β4-subunit and promotes Purkinje cell firing by slowing the decay of resurgent Na+ current.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

24 September 2018

Oxaliplatin-induced neurotoxicity: changes in axonal excitability precede development of neuropathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

24 September 2018

Involvement of increased expression of transient receptor potential melastatin 8 in oxaliplatin-induced cold allodynia in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

24 September 2018

The effects of oxaliplatin, an anticancer drug, on potassium channels of the peripheral myelinated nerve fibres of the adult rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

24 September 2018

Developmental expression of Na+ currents in mouse Purkinje neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

24 September 2018

Participation of sodium currents in burst generation and control of membrane excitability in mesencephalic trigeminal neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

24 September 2018

Open-channel block by the cytoplasmic tail of sodium channel beta4 as a mechanism for resurgent sodium current

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

24 September 2018

Oxaliplatin-induced neurotoxicity: acute hyperexcitability and chronic neuropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

24 September 2018

Subthreshold sodium currents and pacemaking of subthalamic neurons: modulation by slow inactivation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

24 September 2018

The contribution of resurgent sodium current to high-frequency firing in Purkinje neurons: an experimental and modeling study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

24 September 2018

A possible explanation for a neurotoxic effect of the anticancer agent oxaliplatin on neuronal voltage-gated sodium channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

24 September 2018

The chemotherapeutic oxaliplatin alters voltage-gated Na(+) channel kinetics on rat sensory neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

24 September 2018

Oxaliplatin: a review of preclinical and clinical studies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

24 September 2018

Resurgent sodium current and action potential formation in dissociated cerebellar Purkinje neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

24 September 2018

Low-threshold, persistent sodium current in rat large dorsal root ganglion neurons in culture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

24 September 2018

Mutation detection in the med and medJ alleles of the sodium channel Scn8a. Unusual splicing due to a minor class AT-AC intron.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340057

24 September 2018

Modal gating of Na+ channels as a mechanism of persistent Na+ current in pyramidal neurons from rat and cat sensorimotor cortex.

1 reference

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24 September 2018

Nav1.6 channels generate resurgent sodium currents in spinal sensory neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/22493249

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Na currents and action potentials in rat myelinated nerve fibres at 20 and 37 degrees C

1 reference

https://pubmed.ncbi.nlm.nih.gov/22493249

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Voltage-clamp and current-clamp recordings from mammalian DRG neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/22493249

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sustained increase in the excitability of myelinated peripheral axons to depolarizing current is mediated by Nav1.6.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22493249

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.1118058109

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Europe PubMed Central

11 August 2017

2012PNAS..109.6704S

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1 reference

Europe PubMed Central

11 August 2017

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Europe PubMed Central

11 August 2017

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