Inhibition of heat shock protein (molecular weight 90 kDa) attenuates proinflammatory cytokines and prevents lipopolysaccharide-induced liver injury in mice. (Q35930087)

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scientific article published on 18 March 2012

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English	Inhibition of heat shock protein (molecular weight 90 kDa) attenuates proinflammatory cytokines and prevents lipopolysaccharide-induced liver injury in mice.	scientific article published on 18 March 2012

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17 January 2020

Inhibition of heat shock protein (molecular weight 90 kDa) attenuates proinflammatory cytokines and prevents lipopolysaccharide-induced liver injury in mice (English)

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17 January 2020

lipopolysaccharide

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17 January 2020

Pranoti S. Mandrekar

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17 January 2020

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Donna Catalano

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17 January 2020

Arlene Lim

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17 January 2020

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18 March 2012

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17 January 2020

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17 January 2020

55

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17 January 2020

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17 January 2020

1585-1595

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17 January 2020

A phase I study of the heat shock protein 90 inhibitor alvespimycin (17-DMAG) given intravenously to patients with advanced solid tumors

1 reference

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1 reference

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Heat-shock Protein 90 Is Essential for Stabilization of the Hepatitis C Virus Nonstructural Protein NS3

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Alcohol exposure regulates heat shock transcription factor binding and heat shock proteins 70 and 90 in monocytes and macrophages: implication for TNF-alpha regulation

1 reference

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Heat shock co-activates interleukin-8 transcription.

1 reference

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Innate immunity meets with cellular stress at the IKK complex: regulation of the IKK complex by HSP70 and HSP90.

1 reference

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2 October 2017

Signaling mechanisms in alcoholic liver injury: role of transcription factors, kinases and heat shock proteins

1 reference

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2 October 2017

Heat shock protein 90 inhibitors prolong survival, attenuate inflammation, and reduce lung injury in murine sepsis

1 reference

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2 October 2017

Inhibition of Hsp90 attenuates inflammation in endotoxin-induced uveitis

1 reference

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2 October 2017

Hsp90 inhibitors suppress HCV replication in replicon cells and humanized liver mice

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2 October 2017

Geldanamycin interferes with the 90-kDa heat shock protein, affecting lipopolysaccharide-mediated interleukin-1 expression and apoptosis within macrophages

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A central role for the Hsp90.Cdc37 molecular chaperone module in interleukin-1 receptor-associated-kinase-dependent signaling by toll-like receptors.

1 reference

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Heat-shock protein 70 and heat-shock protein 90 associate with Toll-like receptor 4 in response to bacterial lipopolysaccharide

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Bacterial endotoxin modifies heat shock factor-1 activity in RAW 264.7 cells: implications for TNF-alpha regulation during exposure to febrile range temperatures

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Requirement of Hsp90 activity for IkappaB kinase (IKK) biosynthesis and for constitutive and inducible IKK and NF-kappaB activation.

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Role of lipopolysaccharide-binding protein in early alcohol-induced liver injury in mice

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Fluorescence recovery after photobleaching reveals that LPS rapidly transfers from CD14 to hsp70 and hsp90 on the cell membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/22105779

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lung and liver injury following hepatic ischemia/reperfusion in the rat is increased by exogenous lipopolysaccharide which also increases hepatic TNF production in vivo and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/22105779

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heat shock transcription factor 1 opens chromatin structure of interleukin-6 promoter to facilitate binding of an activator or a repressor

1 reference

https://pubmed.ncbi.nlm.nih.gov/22105779

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1002/HEP.24802

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Europe PubMed Central

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17 January 2020

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Europe PubMed Central

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17 January 2020

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Europe PubMed Central

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17 January 2020

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