Robust full-length hepatitis C virus genotype 2a and 2b infectious cultures using mutations identified by a systematic approach applicable to patient strains. (Q35935502)

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English	Robust full-length hepatitis C virus genotype 2a and 2b infectious cultures using mutations identified by a systematic approach applicable to patient strains.	scientific article

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27 January 2020

Robust full-length hepatitis C virus genotype 2a and 2b infectious cultures using mutations identified by a systematic approach applicable to patient strains (English)

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27 January 2020

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based on heuristic

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Hepatitis C virus

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based on heuristic

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based on heuristic

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Santseharay Ramírez

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27 January 2020

Judith M Gottwein

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27 January 2020

Troels K Scheel

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27 January 2020

Robert H. Purcell

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Robert H Purcell

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Yi-Ping Li

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Lotte Mikkelsen

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30 March 2012

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Proceedings of the National Academy of Sciences of the United States of America

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109

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18

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E1101-10

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27 January 2020

Preliminary study of two antiviral agents for hepatitis C genotype 1.

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2 October 2017

Identification of the Niemann-Pick C1-like 1 cholesterol absorption receptor as a new hepatitis C virus entry factor

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Non-genotype-specific role of the hepatitis C virus 5' untranslated region in virus production and in inhibition by interferon

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Hypervariable region 1 differentially impacts viability of hepatitis C virus strains of genotypes 1 to 6 and impairs virus neutralization

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NMR Structure and Ion Channel Activity of the p7 Protein from Hepatitis C Virus

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RNA polymerase activity and specific RNA structure are required for efficient HCV replication in cultured cells

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Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect

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Challenge pools of hepatitis C virus genotypes 1-6 prototype strains: replication fitness and pathogenicity in chimpanzees and human liver-chimeric mouse models

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Development of an intergenotypic hepatitis C virus (HCV) cell culture method to assess antiviral susceptibilities and resistance development of HCV NS3 protease genes from HCV genotypes 1 to 6

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Structural and Functional Analysis of Hepatitis C Virus Strain JFH1 Polymerase

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Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

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Production of Infectious Genotype 1b Virus Particles in Cell Culture and Impairment by Replication Enhancing Mutations

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Highly efficient JFH1-based cell-culture system for hepatitis C virus genotype 5a: failure of homologous neutralizing-antibody treatment to control infection.

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Interferon-based therapy for chronic hepatitis C: current and future perspectives

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Structural determinants for membrane association and dynamic organization of the hepatitis C virus NS3-4A complex

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Molecular Mechanism of Hepatitis C Virus Replicon Variants with Reduced Susceptibility to a Benzofuran Inhibitor, HCV-796

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2 October 2017

Previously Infected Chimpanzees Are Not Consistently Protected against Reinfection or Persistent Infection after Reexposure to the Identical Hepatitis C Virus Strain

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2 October 2017

Advantages of a single-cycle production assay to study cell culture-adaptive mutations of hepatitis C virus

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Development of JFH1-based cell culture systems for hepatitis C virus genotype 4a and evidence for cross-genotype neutralization

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Robust hepatitis C genotype 3a cell culture releasing adapted intergenotypic 3a/2a (S52/JFH1) viruses.

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2 October 2017

Cell Culture Adaptation of Hepatitis C Virus and In Vivo Viability of an Adapted Variant

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2 October 2017

Robust production of infectious viral particles in Huh-7 cells by introducing mutations in hepatitis C virus structural proteins

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2 October 2017

Alanine Scanning of the Hepatitis C Virus Core Protein Reveals Numerous Residues Essential for Production of Infectious Virus

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2 October 2017

The NS3 Helicase and NS5B-to-3'X Regions Are Important for Efficient Hepatitis C Virus Strain JFH-1 Replication in Huh7 Cells

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Replication of hepatitis C virus

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Compensatory Mutations in E1, p7, NS2, and NS3 Enhance Yields of Cell Culture-Infectious Intergenotypic Chimeric Hepatitis C Virus

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Persistent Hepatitis C Virus Infection In Vitro: Coevolution of Virus and Host

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Consensus proposals for a unified system of nomenclature of hepatitis C virus genotypes

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Complete replication of hepatitis C virus in cell culture

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Robust hepatitis C virus infection in vitro

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2 October 2017

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2 October 2017

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24 September 2018

Identifiers

10.1073/PNAS.1203829109

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27 January 2020

2012PNAS..109E1101L

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27 January 2020

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27 January 2020

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