A polymeric nanoparticle formulation of curcumin (NanoCurc™) ameliorates CCl4-induced hepatic injury and fibrosis through reduction of pro-inflammatory cytokines and stellate cell activation. (Q35939307)

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English	A polymeric nanoparticle formulation of curcumin (NanoCurc™) ameliorates CCl4-induced hepatic injury and fibrosis through reduction of pro-inflammatory cytokines and stellate cell activation.	scientific article

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5 February 2020

A polymeric nanoparticle formulation of curcumin (NanoCurc™) ameliorates CCl4-induced hepatic injury and fibrosis through reduction of pro-inflammatory cytokines and stellate cell activation (English)

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5 February 2020

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Anirban Maitra

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Savita Bisht

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Mehtab A Khan

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Mena Bekhit

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Haibo Bai

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Masamichi Mizuma

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Michelle A Rudek

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Ming Zhao

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Amarnath Maitra

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Balmiki Ray

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Debomoy Lahiri

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Robert A Anders

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20 June 2011

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5 February 2020

Laboratory Investigation

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91

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5 February 2020

1383-1395

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5 February 2020

describes a project that uses

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3345948/fullTextXML

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Reactive oxygen and mechanisms of inflammatory liver injury: Present concepts

1 reference

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2 October 2017

Systemic administration of polymeric nanoparticle-encapsulated curcumin (NanoCurc) blocks tumor growth and metastases in preclinical models of pancreatic cancer.

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2 October 2017

Mechanisms of immune-mediated liver injury

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2 October 2017

Curcumin attenuates the effects of insulin on stimulating hepatic stellate cell activation by interrupting insulin signaling and attenuating oxidative stress

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2 October 2017

Bioavailability and activity of phytosome complexes from botanical polyphenols: the silymarin, curcumin, green tea, and grape seed extracts

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2 October 2017

Molecular pathogenesis of liver fibrosis

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2 October 2017

Mononuclear cells in liver fibrosis

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2 October 2017

Systemic delivery of curcumin: 21st century solutions for an ancient conundrum

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2 October 2017

Hepatic fibrosis

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2 October 2017

Diverse roles of invariant natural killer T cells in liver injury and fibrosis induced by carbon tetrachloride

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2 October 2017

In vivo characterization of a polymeric nanoparticle platform with potential oral drug delivery capabilities

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2 October 2017

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2 October 2017

Phase II trial of curcumin in patients with advanced pancreatic cancer

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2 October 2017

Curcuminoids inhibit multiple human cytochromes P450, UDP-glucuronosyltransferase, and sulfotransferase enzymes, whereas piperine is a relatively selective CYP3A4 inhibitor

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2 October 2017

Activation of peroxisome proliferator-activated receptor-gamma by curcumin blocks the signaling pathways for PDGF and EGF in hepatic stellate cells

1 reference

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Bioavailability of curcumin: problems and promises

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2 October 2017

Innate immune response and hepatic inflammation

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2 October 2017

De novo synthesis of glutathione is a prerequisite for curcumin to inhibit hepatic stellate cell (HSC) activation

1 reference

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2 October 2017

Pharmacokinetics and pharmacodynamics of curcumin

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2 October 2017

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Polymeric nanoparticle-encapsulated curcumin ("nanocurcumin"): a novel strategy for human cancer therapy

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2 October 2017

Mouse models of liver fibrosis

1 reference

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2 October 2017

Comparison of systemic availability of curcumin with that of curcumin formulated with phosphatidylcholine

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2 October 2017

Multi-functional polymeric nanoparticles for tumour-targeted drug delivery

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2 October 2017

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2 October 2017

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2 October 2017

Innate immunity in the liver

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2 October 2017

Detection of curcumin and its metabolites in hepatic tissue and portal blood of patients following oral administration

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2 October 2017

Cancer risk and diet in India

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2 October 2017

An immortalized rat liver stellate cell line (HSC-T6): a new cell model for the study of retinoid metabolism in vitro.

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2 October 2017

Transforming growth factor beta1 induces the expression of alpha1(I) procollagen mRNA by a hydrogen peroxide-C/EBPbeta-dependent mechanism in rat hepatic stellate cells

1 reference

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2 October 2017

Molecular mechanisms of hepatic fibrosis and principles of therapy

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2 October 2017

Transdifferentiation of hepatic stellate cells (Ito cells) to myofibroblasts: a key event in hepatic fibrogenesis

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2 October 2017

Curcumin, an anti-tumour promoter and anti-inflammatory agent, inhibits induction of nitric oxide synthase in activated macrophages

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2 October 2017

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11 July 2018

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11 July 2018

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1 reference

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11 July 2018

Antioxidant activity of curcumin and related compounds

1 reference

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11 July 2018

CD1d-restricted natural killer T cells contribute to hepatic inflammation and fibrogenesis in mice.

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24 September 2018

Curcumin Enhances Oral Bioavailability and Anti-Tumor Therapeutic Efficacy of Paclitaxel upon Administration in Nanoemulsion Formulation

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24 September 2018

Amelioration of hepatic fibrosis via Padma Hepaten is associated with altered natural killer T lymphocytes

1 reference

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24 September 2018

Structure-activity relationships for the inhibition of recombinant human cytochromes P450 by curcumin analogues

1 reference

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24 September 2018

Curcumin protects the rat liver from CCl4-caused injury and fibrogenesis by attenuating oxidative stress and suppressing inflammation

1 reference

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24 September 2018

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1 reference

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24 September 2018

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1 reference

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24 September 2018

Natural killer cells ameliorate liver fibrosis by killing activated stellate cells in NKG2D-dependent and tumor necrosis factor-related apoptosis-inducing ligand-dependent manners

1 reference

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24 September 2018

The effects of curcumin on depressive-like behaviors in mice

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24 September 2018

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1 reference

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1 reference

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24 September 2018

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1 reference

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24 September 2018

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1 reference

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24 September 2018

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1 reference

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24 September 2018

Peroxisome proliferator-activated receptor gamma transcriptional regulation is involved in platelet-derived growth factor-induced proliferation of human hepatic stellate cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21691262

12 December 2020

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inferred from PubMed ID database lookup

Collagen production by rat liver fat-storing cells in primary culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/21691262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/21691262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of Ly6G-specific monoclonal antibody to deplete neutrophils in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21691262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ligands of peroxisome proliferator-activated receptor γ modulate profibrogenic and proinflammatory actions in hepatic stellate cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21691262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic recruitment of the inflammatory Gr1+monocyte subset upon liver injury promotes hepatic fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21691262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-inflammatory activity of curcumin analogues

1 reference

https://pubmed.ncbi.nlm.nih.gov/21691262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antihepatotoxic principles of Curcuma longa rhizomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21691262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effect of curcumin in rat liver injury induced by carbon tetrachloride

1 reference

https://pubmed.ncbi.nlm.nih.gov/21691262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/21691262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accumulation and cellular localization of fibrinogen/fibrin during shortterm and longterm rat liver injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/21691262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/LABINVEST.2011.86

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21691262%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

PMC publication ID

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Europe PubMed Central

PMC publication ID

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5 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

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5 February 2020

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