Alpharetroviral self-inactivating vectors: long-term transgene expression in murine hematopoietic cells and low genotoxicity. (Q35939492)

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23 January 2020

title

Alpharetroviral self-inactivating vectors: long-term transgene expression in murine hematopoietic cells and low genotoxicity (English)

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23 January 2020

3

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Kerstin B Kaufmann

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7

Manfred Schmidt

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23 January 2020

author name string

Julia D Suerth

1

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23 January 2020

Tobias Maetzig

2

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23 January 2020

Niels Heinz

4

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23 January 2020

Jens-Uwe Appelt

5

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23 January 2020

Manuel Grez

8

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23 January 2020

Ute Modlich

9

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23 January 2020

Christopher Baum

10

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23 January 2020

Axel Schambach

11

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23 January 2020

publication date

14 February 2012

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23 January 2020

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23 January 2020

volume

20

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23 January 2020

issue

5

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23 January 2020

page(s)

1022-1032

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Self-inactivating alpharetroviral vectors with a split-packaging design

23 January 2020

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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7 January 2021

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Inverse targeting of retroviral vectors: selective gene transfer in a mixed population of hematopoietic and nonhematopoietic cells.

1 reference

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Lack of expression from a retroviral vector after transduction of murine hematopoietic stem cells is associated with methylation in vivo

2 October 2017

1 reference

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Polyclonal fluctuation of lentiviral vector-transduced and expanded murine hematopoietic stem cells.

2 October 2017

1 reference

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Comprehensive genomic access to vector integration in clinical gene therapy

24 September 2018

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QuickMap: a public tool for large-scale gene therapy vector insertion site mapping and analysis

24 September 2018

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Retroviral insertion site analysis in dominant haematopoietic clones

24 September 2018

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Comparison of HIV-derived lentiviral and MLV-based gammaretroviral vector integration sites in primate repopulating cells

24 September 2018

1 reference

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Design and synthesis of 3,7-diarylimidazopyridines as inhibitors of the VEGF-receptor KDR.

24 September 2018

1 reference

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Lentiviral vector transduction of NOD/SCID repopulating cells results in multiple vector integrations per transduced cell: risk of insertional mutagenesis

24 September 2018

1 reference

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Detection and direct genomic sequencing of multiple rare unknown flanking DNA in highly complex samples

24 September 2018

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Equal potency of gammaretroviral and lentiviral SIN vectors for expression of O6-methylguanine-DNA methyltransferase in hematopoietic cells

24 September 2018

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12 December 2020

Leukemia induction after a single retroviral vector insertion in Evi1 or Prdm16

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12 December 2020

CD133-positive hematopoietic stem cell "stemness" genes contain many genes mutated or abnormally expressed in leukemia

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12 December 2020

Upregulation of Flt3 expression within the bone marrow Lin(-)Sca1(+)c-kit(+) stem cell compartment is accompanied by loss of self-renewal capacity

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12 December 2020

In vivo self-renewal of c-Kit+ Sca-1+ Lin(low/-) hemopoietic stem cells

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12 December 2020

Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell

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12 December 2020

Identifiers

DOI

10.1038/MT.2011.309

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22334016%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22334016%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

PubMed publication ID

22334016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22334016%20AND%20SRC:MED&resulttype=core&format=json