Manipulating the type 1 vs type 2 balance in type 1 diabetes (Q35942439)

11 August 2017

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title

Manipulating the type 1 vs type 2 balance in type 1 diabetes (English)

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11 August 2017

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Urs Christen

1

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11 August 2017

Matthias G von Herrath

series ordinal

2

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11 August 2017

publication date

1 January 2004

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11 August 2017

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11 August 2017

volume

30

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11 August 2017

issue

3

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11 August 2017

page(s)

309-325

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https://scigraph.springernature.com/pub.10.1385/ir:30:3:309

11 August 2017

exact match

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cites work

A new look at viruses in type 1 diabetes

1 reference

12 December 2020

Early expression of interferon-gamma inducible protein 10 and monokine induced by interferon-gamma in cardiac allografts is mediated by CD8+ T cells.

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12 December 2020

Viruses, cytokines, antigens, and autoimmunity

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12 December 2020

More stringent conditions of plasmid DNA vaccination are required to protect grafted versus endogenous islets in nonobese diabetic mice

1 reference

12 December 2020

Cellular immunity to a determinant common to glutamate decarboxylase and coxsackie virus in insulin-dependent diabetes

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12 December 2020

Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice

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12 December 2020

Mechanism underlying counterregulation of autoimmune diabetes by IL-4.

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12 December 2020

Differential chemokine gene expression in corneal transplant rejection

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12 December 2020

Costimulator B7-1 confers antigen-presenting-cell function to parenchymal tissue and in conjunction with tumor necrosis factor alpha leads to autoimmunity in transgenic mice

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12 December 2020

Neutralization of IFN-inducible protein 10/CXCL10 exacerbates experimental autoimmune encephalomyelitis.

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12 December 2020

Peripheral tolerance to an islet cell-specific hemagglutinin transgene affects both CD4+ and CD8+ T cells

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12 December 2020

Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene

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12 December 2020

Apoptosis of autoreactive CD8 lymphocytes as a potential mechanism for the abrogation of type 1 diabetes by islet-specific TNF-alpha expression at a time when the autoimmune process is already ongoing.

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12 December 2020

Insulin-dependent diabetes mellitus induced in transgenic mice by ectopic expression of class II MHC and interferon-gamma

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12 December 2020

On the various manifestations of spontaneous autoimmune diabetes in rodent models

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12 December 2020

Interferon-gamma is essential for destruction of beta cells and development of insulin-dependent diabetes mellitus

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12 December 2020

Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases.

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12 December 2020

Immunological tolerance to a pancreatic antigen as a result of local expression of TNFalpha by islet beta cells

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12 December 2020

Amino acid homology between the encephalitogenic site of myelin basic protein and virus: mechanism for autoimmunity

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12 December 2020

TGF-beta 1 overexpression in murine pancreas induces chronic pancreatitis and, together with TNF-alpha, triggers insulin-dependent diabetes

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12 December 2020

Differentiation of human NK cells into NK1 and NK2 subsets.

1 reference

12 December 2020

Molecular mimicry by herpes simplex virus-type 1: autoimmune disease after viral infection.

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12 December 2020

Among CXCR3 chemokines, IFN-gamma-inducible protein of 10 kDa (CXC chemokine ligand (CXCL) 10) but not monokine induced by IFN-gamma (CXCL9) imprints a pattern for the subsequent development of autoimmune disease.

1 reference

12 December 2020

Selective up-regulation of chemokine receptors CCR4 and CCR8 upon activation of polarized human type 2 Th cells

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12 December 2020

What can stochastic resonance do?

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12 December 2020

Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s

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12 December 2020

T-cell subsets: chemokine receptors guide the way.

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12 December 2020

The role of chemokine receptors in primary, effector, and memory immune responses

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12 December 2020

Inhibition of Th1 Development Mediated by GATA-3 through an IL-4-Independent Mechanism

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12 December 2020

Islet-specific expression of IL-10 promotes diabetes in nonobese diabetic mice independent of Fas, perforin, TNF receptor-1, and TNF receptor-2 molecules

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12 December 2020

The role of viruses and environmental factors in the induction of diabetes

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12 December 2020

IL-10 impacts autoimmune diabetes via a CD8+ T cell pathway circumventing the requirement for CD4+ T and B lymphocytes

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12 December 2020

TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

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12 December 2020

Antigen-presenting cells in adoptively transferred and spontaneous autoimmune diabetes

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12 December 2020

How virus induces a rapid or slow onset insulin-dependent diabetes mellitus in a transgenic model

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12 December 2020

Expression of the chemokine receptor CXCR3 and its ligand IP-10 during human cardiac allograft rejection

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12 December 2020

Focal expression of interleukin-2 does not break unresponsiveness to "self" (viral) antigen expressed in beta cells but enhances development of autoimmune disease (diabetes) after initiation of an anti-self immune response

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12 December 2020

Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice

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12 December 2020

Local expression of TNFalpha in neonatal NOD mice promotes diabetes by enhancing presentation of islet antigens

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12 December 2020

T cell cross-reactivity between coxsackievirus and glutamate decarboxylase is associated with a murine diabetes susceptibility allele

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12 December 2020

TNF-alpha down-regulates type 1 cytokines and prolongs survival of syngeneic islet grafts in nonobese diabetic mice

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12 December 2020

The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD.

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12 December 2020

Myelin basic protein-specific T helper 2 (Th2) cells cause experimental autoimmune encephalomyelitis in immunodeficient hosts rather than protect them from the disease

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12 December 2020

Breeding of a non-obese, diabetic strain of mice

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12 December 2020

Cure of prediabetic mice by viral infections involves lymphocyte recruitment along an IP-10 gradient

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12 December 2020

Pancreatic islet production of murine interleukin-10 does not inhibit immune-mediated tissue destruction

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12 December 2020

Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process

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12 December 2020

Changes in function of antigen-specific lymphocytes correlating with progression towards diabetes in a transgenic model.

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12 December 2020

Neutralization of the chemokine CXCL10 reduces inflammatory cell invasion and demyelination and improves neurological function in a viral model of multiple sclerosis

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12 December 2020

Suppression of diabetes in nonobese diabetic mice by oral administration of porcine insulin

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12 December 2020

Plasmid DNA encoding IFN-gamma-inducible protein 10 redirects antigen-specific T cell polarization and suppresses experimental autoimmune encephalomyelitis

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12 December 2020

T helper 2 cells are subject to high dose oral tolerance and are not essential for its induction

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12 December 2020

The expanding universe of T-cell subsets: Th1, Th2 and more.

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12 December 2020

Neonatal tumor necrosis factor alpha promotes diabetes in nonobese diabetic mice by CD154-independent antigen presentation to CD8(+) T cells.

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12 December 2020

A cell culture model for T lymphocyte clonal anergy

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12 December 2020

The temporal importance of TNFalpha expression in the development of diabetes

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12 December 2020

Identification of CRG-2. An interferon-inducible mRNA predicted to encode a murine monokine

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12 December 2020

Viruses as therapeutic agents. I. Treatment of nonobese insulin-dependent diabetes mice with virus prevents insulin-dependent diabetes mellitus while maintaining general immune competence

1 reference

12 December 2020

Selective recruitment of CCR4-bearing Th2 cells toward antigen-presenting cells by the CC chemokines thymus and activation-regulated chemokine and macrophage-derived chemokine

1 reference

12 December 2020

CXCL10 (IFN-gamma-inducible protein-10) control of encephalitogenic CD4+ T cell accumulation in the central nervous system during experimental autoimmune encephalomyelitis.

1 reference

12 December 2020

Differential expression of chemokines and chemokine receptors shapes the inflammatory response in rejecting human liver transplants

1 reference

12 December 2020

Chemokines--chemotactic cytokines that mediate inflammation

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12 December 2020

Rubella infection and diabetes mellitus

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12 December 2020

Prevention of type I diabetes in nonobese diabetic mice by virus infection

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12 December 2020

The Th1/Th2 balance in autoimmunity

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12 December 2020

Early chemokine cascades in murine cardiac grafts regulate T cell recruitment and progression of acute allograft rejection

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12 December 2020

Plasmid DNAs encoding insulin and glutamic acid decarboxylase 65 have distinct effects on the progression of autoimmune diabetes in nonobese diabetic mice

1 reference

12 December 2020

Suppression of T(h)1 cell activation and prevention of autoimmune diabetes in NOD mice by local expression of viral IL-10

1 reference

12 December 2020

Prevention of diabetes in nonobese diabetic mice by tumor necrosis factor (TNF): similarities between TNF-alpha and interleukin 1.

1 reference

12 December 2020

Intraallograft chemokine RNA and protein during rejection of MHC-matched/multiple minor histocompatibility-disparate skin grafts

1 reference

12 December 2020

A dual role for TNF-alpha in type 1 diabetes: islet-specific expression abrogates the ongoing autoimmune process when induced late but not early during pathogenesis

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12 December 2020

Prevention of autoimmune insulitis by delivery of a chimeric plasmid encoding interleukin-4 and interleukin-10.

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12 December 2020

GATA-3 induces T helper cell type 2 (Th2) cytokine expression and chromatin remodeling in committed Th1 cells

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12 December 2020

Antigen-specific mediated suppression of beta cell autoimmunity by plasmid DNA vaccination

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12 December 2020

Antigen-induced regulatory T cells in autoimmunity

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12 December 2020

Requirement of the chemokine receptor CXCR3 for acute allograft rejection

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12 December 2020

Active suppression of diabetes after oral administration of insulin is determined by antigen dosage

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12 December 2020

Molecular mimicry as a mechanism for the cause and a probe uncovering etiologic agent(s) of autoimmune disease

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12 December 2020

The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4.

1 reference

12 December 2020

Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in nonobese diabetic (NOD) mice

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12 December 2020

Expression of chemokines and chemokine receptors during human renal transplant rejection

1 reference

12 December 2020

Monoclonal anti-tumor necrosis factor antibody renders non-obese diabetic mice hypersensitive to irradiation and enhances insulitis development

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12 December 2020

Abrogation of autoimmune diabetes in nonobese diabetic mice and protection against effector lymphocytes by transgenic paracrine TGF-beta1

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12 December 2020

The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

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12 December 2020

Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: role of anti-self (virus) immune response

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12 December 2020

Congenital rubella, insulitis, and diabetes mellitus in an infant

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12 December 2020

A novel transcription factor, T-bet, directs Th1 lineage commitment

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12 December 2020

Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes

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12 December 2020

Pathogenesis and treatment of virus-induced autoimmune diabetes: novel insights gained from the RIP-LCMV transgenic mouse model

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12 December 2020

Targeting the function of IFN-gamma-inducible protein 10 suppresses ongoing adjuvant arthritis.

1 reference

12 December 2020

Molecular mimicry and autoimmune disease

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12 December 2020

Cross reactivity of three T cell attracting murine chemokines stimulating the CXC chemokine receptor CXCR3 and their induction in cultured cells and during allograft rejection.

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12 December 2020

Biochemical characterization of a gamma interferon-inducible cytokine (IP-10).

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12 December 2020

Chronic tumor necrosis factor alters T cell responses by attenuating T cell receptor signaling

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12 December 2020

Cxcr3 and its ligand CXCL10 are expressed by inflammatory cells infiltrating lung allografts and mediate chemotaxis of T cells at sites of rejection

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12 December 2020

Functional diversity of helper T lymphocytes

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12 December 2020

Production of interleukin 10 by islet cells accelerates immune-mediated destruction of beta cells in nonobese diabetic mice

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12 December 2020

The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

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12 December 2020

TGF-beta induced by oral tolerance ameliorates experimental tracheal eosinophilia

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12 December 2020

Reversal of established autoimmune diabetes by restoration of endogenous beta cell function

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12 December 2020

Loss of pancreatic islet tolerance induced by beta-cell expression of interferon-gamma

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12 December 2020

Human chemokines: an update

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12 December 2020

Final steps of natural killer cell maturation: a model for type 1-type 2 differentiation?

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12 December 2020

Pancreatic IL-4 expression results in islet-reactive Th2 cells that inhibit diabetogenic lymphocytes in the nonobese diabetic mouse.

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12 December 2020

Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens

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12 December 2020

A role for non-MHC genetic polymorphism in susceptibility to spontaneous autoimmunity

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12 December 2020

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12 December 2020

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

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12 December 2020

DNA immunization to prevent autoimmune diabetes

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12 December 2020

The biology of chemokines and their receptors

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12 December 2020

Oral insulin treatment suppresses virus-induced antigen-specific destruction of beta cells and prevents autoimmune diabetes in transgenic mice

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12 December 2020

Endogenous expression levels of autoantigens influence success or failure of DNA immunizations to prevent type 1 diabetes: addition of IL-4 increases safety

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12 December 2020

Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses

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12 December 2020

Adeno-associated virus-mediated IL-10 gene therapy inhibits diabetes recurrence in syngeneic islet cell transplantation of NOD mice.

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12 December 2020

Consequences of in situ production of IL-2 for islet cell death.

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12 December 2020

Molecular mechanisms regulating Th1 immune responses

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12 December 2020

Virus-induced autoimmune diabetes: most beta-cells die through inflammatory cytokines and not perforin from autoreactive (anti-viral) cytotoxic T-lymphocytes.

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12 December 2020

T cell infiltration into class II MHC-disparate allografts and acute rejection is dependent on the IFN-gamma-induced chemokine Mig

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12 December 2020

Interleukin-4 acts at the locus of the antigen-presenting dendritic cell to counter-regulate cytotoxic CD8+ T-cell responses.

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12 December 2020

Chemokines and their receptors in allograft rejection

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12 December 2020

Microorganisms and autoimmunity: making the barren field fertile?

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12 December 2020

T cell tolerance by clonal elimination in the thymus

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12 December 2020

An update on cytokines in the pathogenesis of insulin-dependent diabetes mellitus

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12 December 2020

Chemokines: a new classification system and their role in immunity

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12 December 2020

Beta cells are responsible for CXCR3-mediated T-cell infiltration in insulitis

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12 December 2020

T Cell Reactivity to MHC Molecules: Immunity Versus Tolerance

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12 December 2020

Local expression of transgene encoded TNF alpha in islets prevents autoimmune diabetes in nonobese diabetic (NOD) mice by preventing the development of auto-reactive islet-specific T cells

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12 December 2020

Autoreactive CD4+ T cells protect from autoimmune diabetes via bystander suppression using the IL-4/Stat6 pathway.

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12 December 2020

Molecular role of TGF-beta, secreted from a new type of CD4+ suppressor T cell, NY4.2, in the prevention of autoimmune IDDM in NOD mice

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12 December 2020

Dendritic cell lineage, plasticity and cross-regulation

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12 December 2020

Genetic requirements for acceleration of diabetes in non-obese diabetic mice expressing interleukin-2 in islet beta-cells

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12 December 2020

Signaling and transcription in T helper development

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12 December 2020

Insulin-dependent diabetes mellitus and its animal models.

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12 December 2020

Identifiers

DOI

10.1385/IR:30:3:309

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Dimensions Publication ID

11 August 2017

1039913402

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