Dose-dependent treatment of optic nerve crush by exogenous systemic mutant erythropoietin (Q35952654)

11 August 2017

Dose-dependent treatment of optic nerve crush by exogenous systemic mutant erythropoietin (English)

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11 August 2017

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Timothy A Sullivan

1

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11 August 2017

Eldon E Geisert

series ordinal

2

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11 August 2017

Justin P Templeton

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3

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11 August 2017

Tonia S Rex

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4

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11 August 2017

27 January 2012

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Experimental Eye Research

11 August 2017

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11 August 2017

96

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11 August 2017

1

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11 August 2017

36-41

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describes a project that uses

11 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3350094/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Systemic adeno-associated virus-mediated gene therapy preserves retinal ganglion cells and visual function in DBA/2J glaucomatous mice

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Therapeutic approaches to multiple sclerosis: an update on failed, interrupted, or inconclusive trials of neuroprotective and alternative treatment strategies

2 October 2017

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The WldS gene delays axonal but not somatic degeneration in a rat glaucoma model

2 October 2017

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Axons of retinal ganglion cells are insulted in the optic nerve early in DBA/2J glaucoma

2 October 2017

1 reference

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Dominant inheritance of retinal ganglion cell resistance to optic nerve crush in mice

2 October 2017

1 reference

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Retinal stem cells transplanted into models of late stages of retinitis pigmentosa preferentially adopt a glial or a retinal ganglion cell fate

2 October 2017

1 reference

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Neuroprotection by hypoxic preconditioning: HIF-1 and erythropoietin protect from retinal degeneration

2 October 2017

1 reference

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The effect of experimental glaucoma and optic nerve transection on amacrine cells in the rat retina

2 October 2017

1 reference

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Susceptibility to neurodegeneration in a glaucoma is modified by Bax gene dosage

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350094

Animal models of optic nerve diseases

2 October 2017

1 reference

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Constitutive overexpression of human erythropoietin protects the mouse retina against induced but not inherited retinal degeneration

2 October 2017

1 reference

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Deconstructing the axon: Wallerian degeneration and the ubiquitin-proteasome system

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350094

HIF-1-induced erythropoietin in the hypoxic retina protects against light-induced retinal degeneration

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350094

Axonal self-destruction and neurodegeneration

2 October 2017

1 reference

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Caspase-9: involvement in secondary death of axotomized rat retinal ganglion cells in vivo

2 October 2017

1 reference

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Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury

2 October 2017

1 reference

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The major cell populations of the mouse retina.

2 October 2017

1 reference

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Erythropoietin and erythropoietin receptor in the developing human central nervous system

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350094

Neuroprotection of photoreceptors by direct delivery of erythropoietin to the retina of the retinal degeneration slow mouse

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350094

Systemic gene delivery protects the photoreceptors in the retinal degeneration slow mouse.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350094

Neuroprotective effect of recombinant human erythropoietin on optic nerve injury in rats.

24 September 2018

1 reference

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The expressions of Fas and caspase-3 in human glaucomatous optic nerve axons.

24 September 2018

1 reference

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Progressive ganglion cell degeneration precedes neuronal loss in a mouse model of glaucoma

24 September 2018

1 reference

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Erythropoietin is both neuroprotective and neuroregenerative following optic nerve transection.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350094

Erythropoietin promotes survival of retinal ganglion cells in DBA/2J glaucoma mice.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350094

Erythropoietin promotes regeneration of adult CNS neurons via Jak2/Stat3 and PI3K/AKT pathway activation

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350094

Gene transfer into skeletal muscle using novel AAV serotypes.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350094

Systemic but not intraocular Epo gene transfer protects the retina from light-and genetic-induced degeneration

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350094

Long-term pharmacologically regulated expression of erythropoietin in primates following AAV-mediated gene transfer.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350094

Derivatives of erythropoietin that are tissue protective but not erythropoietic

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350094

Effect of erythropoietin axotomy-induced apoptosis in rat retinal ganglion cells

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350094

Erytropoietin concentrations in cerebrospinal fluid of nonhuman primates and fetal sheep following high-dose recombinant erythropoietin

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350094

Apoptotic versus necrotic characteristics of retinal ganglion cell death after partial optic nerve injury

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350094

Inhibition of CPP32-like proteases rescues axotomized retinal ganglion cells from secondary cell death in vivo.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350094

Optic nerve damage in human glaucoma. II. The site of injury and susceptibility to damage

24 September 2018

1 reference

12 December 2020

Degeneration of neuronal cell bodies following axonal injury in Wld(S) mice

1 reference

12 December 2020

Up-regulation of Bax protein in degenerating retinal ganglion cells precedes apoptotic cell death after optic nerve lesion in the rat

1 reference

12 December 2020

Regional differences in the structure of the lamina cribrosa and their relation to glaucomatous optic nerve damage

1 reference

12 December 2020

RGC death in mice after optic nerve crush injury: oxidative stress and neuroprotection

1 reference

12 December 2020

GAP-43 expression is upregulated in retinal ganglion cells after ischemia/reperfusion-induced damage

1 reference

12 December 2020

Bax-dependent and independent pathways of retinal ganglion cell death induced by different damaging stimuli

1 reference

12 December 2020

Brain-derived neurotrophic factor-mediated neuroprotection of adult rat retinal ganglion cells in vivo does not exclusively depend on phosphatidyl-inositol-3'-kinase/protein kinase B signaling

1 reference

12 December 2020

Passage of erythropoietic agents across the blood-brain barrier: a comparison of human and murine erythropoietin and the analog darbepoetin alfa

1 reference

12 December 2020

Experimental induction of retinal ganglion cell death in adult mice

1 reference

12 December 2020

10.1016/J.EXER.2012.01.006

Identifiers

DOI

1 reference

11 August 2017

1 reference

11 August 2017

PubMed publication ID

22306016

1 reference