Targeted gene replacement demonstrates that myristoyl-CoA: protein N-myristoyltransferase is essential for viability of Cryptococcus neoformans. (Q35953363)

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English	Targeted gene replacement demonstrates that myristoyl-CoA: protein N-myristoyltransferase is essential for viability of Cryptococcus neoformans.	scientific article

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30 October 2019

Targeted gene replacement demonstrates that myristoyl-CoA: protein N-myristoyltransferase is essential for viability of Cryptococcus neoformans (English)

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30 October 2019

Cryptococcus neoformans

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1

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30 October 2019

Jeffrey I. Gordon

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J I Gordon

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30 October 2019

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E Jackson-Machelski

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30 October 2019

D L Toffaletti

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30 October 2019

J R Perfect

4

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30 October 2019

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1 December 1994

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30 October 2019

Proceedings of the National Academy of Sciences of the United States of America

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30 October 2019

91

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30 October 2019

25

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30 October 2019

12008-12012

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30 October 2019

Gene transfer in Cryptococcus neoformans by use of biolistic delivery of DNA

1 reference

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2 October 2017

Comparison of myristoyl-CoA:protein N-myristoyltransferases from three pathogenic fungi: Cryptococcus neoformans, Histoplasma capsulatum, and Candida albicans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45365

2 October 2017

Human mycoses: drugs and targets for emerging pathogens

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2 October 2017

Cloning of a Cryptococcus neoformans gene, GPA1, encoding a G-protein alpha-subunit homolog.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45365

2 October 2017

Genetic and biochemical studies of protein N-myristoylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45365

2 October 2017

Saccharomyces cerevisiae contains four fatty acid activation (FAA) genes: an assessment of their role in regulating protein N-myristoylation and cellular lipid metabolism

1 reference

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2 October 2017

Suppressors of nmtl-181, a conditional lethal allele of the Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase gene, reveal proteins involved in regulating protein N-myristoylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45365

2 October 2017

Chronic cryptococcal meningitis: a new experimental model in rabbits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45365

2 October 2017

Comparison of amphotericin B and N-D-ornithyl amphotericin B methyl ester in experimental cryptococcal meningitis and Candida albicans endocarditis with pyelonephritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45365

2 October 2017

Comparison of itraconazole and fluconazole in treatment of cryptococcal meningitis and candida pyelonephritis in rabbits

1 reference

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2 October 2017

Isolation of the URA5 gene from Cryptococcus neoformans var. neoformans and its use as a selective marker for transformation

1 reference

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2 October 2017

ADP ribosylation factor is an essential protein in Saccharomyces cerevisiae and is encoded by two genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45365

2 October 2017

Myristic acid auxotrophy caused by mutation of S. cerevisiae myristoyl-CoA:protein N-myristoyltransferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45365

2 October 2017

Isolation of telomerelike sequences from Cryptococcus neoformans and their use in high-efficiency transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45365

2 October 2017

Mutations of human myristoyl-CoA:protein N-myristoyltransferase cause temperature-sensitive myristic acid auxotrophy in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45365

2 October 2017

Molecular and genetic analysis of URA5 transformants of Cryptococcus neoformans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45365

2 October 2017

4-oxatetradecanoic acid is fungicidal for Cryptococcus neoformans and inhibits replication of human immunodeficiency virus I

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45365

2 October 2017

Studies of the catalytic activities and substrate specificities of Saccharomyces cerevisiae myristoyl-coenzyme A: protein N-myristoyltransferase deletion mutants and human/yeast Nmt chimeras in Escherichia coli and S. cerevisiae

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2 October 2017

Extensive allelic variation in Cryptococcus neoformans

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2 October 2017

A comparative analysis of the kinetic mechanism and peptide substrate specificity of human and Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase.

1 reference

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11 July 2018

Isothermal titration calorimetric studies of Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase. Determinants of binding energy and catalytic discrimination among acyl-CoA and peptide ligands.

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11 July 2018

Cryptococcal disease in patients with the acquired immunodeficiency syndrome. Diagnostic features and outcome of treatment.

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11 July 2018

Disruption of the yeast N-myristoyl transferase gene causes recessive lethality.

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11 July 2018

Kinetic and structural evidence for a sequential ordered Bi Bi mechanism of catalysis by Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase

1 reference

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11 July 2018

A placebo-controlled trial of maintenance therapy with fluconazole after treatment of cryptococcal meningitis in the acquired immunodeficiency syndrome. California Collaborative Treatment Group

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11 July 2018

The Candida albicans myristoyl-CoA:protein N-myristoyltransferase gene. Isolation and expression in Saccharomyces cerevisiae and Escherichia coli.

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11 July 2018

Comparison of the acyl chain specificities of human myristoyl-CoA synthetase and human myristoyl-CoA:protein N-myristoyltransferase

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24 September 2018

Cryptococcal meningitis in patients with AIDS

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https://pubmed.ncbi.nlm.nih.gov/7991574

12 December 2020

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Infections with Cryptococcus neoformans in the acquired immunodeficiency syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/7991574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-myristoylation is required for function of the pheromone-responsive G alpha protein of yeast: conditional activation of the pheromone response by a temperature-sensitive N-myristoyl transferase

1 reference

https://pubmed.ncbi.nlm.nih.gov/7991574

12 December 2020

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inferred from PubMed ID database lookup

A controlled trial of fluconazole or amphotericin B to prevent relapse of cryptococcal meningitis in patients with the acquired immunodeficiency syndrome. The NIAID AIDS Clinical Trials Group and Mycoses Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/7991574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.91.25.12008

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30 October 2019

1994PNAS...9112008L

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1 reference

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30 October 2019

1 reference

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30 October 2019

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