Towards a structural view of gating in potassium channels (Q35954286)

11 August 2017

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title

Towards a structural view of gating in potassium channels (English)

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11 August 2017

Kenton J Swartz

1

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11 August 2017

language of work or name

English

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publication date

1 December 2004

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Nature Reviews Neuroscience

11 August 2017

published in

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11 August 2017

volume

5

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11 August 2017

issue

12

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11 August 2017

page(s)

905-916

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The components of membrane conductance in the giant axon of Loligo

11 August 2017

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The activation gate of a voltage-gated K+ channel can be trapped in the open state by an intersubunit metal bridge

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Constitutive activation of the Shaker Kv channel

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The size of gating charge in wild-type and mutant Shaker potassium channels

31 March 2020

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31 March 2020

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31 March 2020

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Effective gating charges per channel in voltage-dependent K+ and Ca2+ channels

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Transfer of twelve charges is needed to open skeletal muscle Na+ channels

31 March 2020

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A neutral amino acid change in segment IIS4 dramatically alters the gating properties of the voltage-dependent sodium channel

31 March 2020

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Alteration of voltage-dependence of Shaker potassium channel by mutations in the S4 sequence

31 March 2020

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Voltage-sensing residues in the S4 region of a mammalian K+ channel

31 March 2020

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Uncharged S4 residues and cooperativity in voltage-dependent potassium channel activation

31 March 2020

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Role of the S4 in cooperativity of voltage-dependent potassium channel activation

31 March 2020

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Mutations in the S4 region isolate the final voltage-dependent cooperative step in potassium channel activation

31 March 2020

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S4 mutations alter gating currents of Shaker K channels

31 March 2020

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Specificity of charge-carrying residues in the voltage sensor of potassium channels

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Direct physical measure of conformational rearrangement underlying potassium channel gating

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Structural implications of fluorescence quenching in the Shaker K+ channel

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Atomic scale movement of the voltage-sensing region in a potassium channel measured via spectroscopy

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Reconstructing voltage sensor-pore interaction from a fluorescence scan of a voltage-gated K+ channel

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Electrostatic interactions of S4 voltage sensor in shaker K+ channel

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Mutation of conserved negatively charged residues in the S2 and S3 transmembrane segments of a mammalian K+ channel selectively modulates channel gating

31 March 2020

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Electrostatic interactions between transmembrane segments mediate folding of Shaker K+ channel subunits

31 March 2020

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alpha-helical structural elements within the voltage-sensing domains of a K(+) channel

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Movement and crevices around a sodium channel S3 segment

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A proton pore in a potassium channel voltage sensor reveals a focused electric field

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Voltage sensor movements

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Molecular movement of the voltage sensor in a K channel

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Stirring up controversy with a voltage sensor paddle.

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Functional analysis of an archaebacterial voltage-dependent K+ channel

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Hanatoxin modifies the gating of a voltage-dependent K+ channel through multiple binding sites

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Mapping the receptor site for hanatoxin, a gating modifier of voltage-dependent K+ channels.

31 March 2020

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The lipid-protein interface of a Shaker K(+) channel

31 March 2020

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Helical structure and packing orientation of the S2 segment in the Shaker K+ channel

31 March 2020

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Transmembrane biogenesis of Kv1.3.

31 March 2020

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Hydrophobicity scales and computational techniques for detecting amphipathic structures in proteins

31 March 2020

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Hydrophobic organization of membrane proteins

31 March 2020

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A photochemical approach to the lipid accessibility of engineered cysteinyl residues

31 March 2020

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Substituted-cysteine accessibility method

31 March 2020

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The principle of gating charge movement in a voltage-dependent K+ channel

31 March 2020

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Kinetics of tethering quaternary ammonium compounds to K(+) channels

31 March 2020

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A membrane-access mechanism of ion channel inhibition by voltage sensor toxins from spider venom

31 March 2020

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31 March 2020

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Molecular surface of tarantula toxins interacting with voltage sensors in K(v) channels

31 March 2020

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Evidence for intersubunit interactions between S4 and S5 transmembrane segments of the Shaker potassium channel

31 March 2020

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Electron microscopic analysis of KvAP voltage-dependent K+ channels in an open conformation

31 March 2020

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The diphtheria toxin channel-forming T domain translocates its own NH2-terminal region across planar bilayers

31 March 2020

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Identification of a translocated protein segment in a voltage-dependent channel

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Translocation of the catalytic domain of diphtheria toxin across planar phospholipid bilayers by its own T domain

31 March 2020

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The structures of BtuCD and MscS and their implications for transporter and channel function

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Crystal structure of Escherichia coli MscS, a voltage-modulated and mechanosensitive channel

31 March 2020

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Detecting rearrangements of shaker and NaChBac in real-time with fluorescence spectroscopy in patch-clamped mammalian cells

31 March 2020

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Structural models of the transmembrane region of voltage-gated and other K+ channels in open, closed, and inactivated conformations

31 March 2020

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Tethered blockers as molecular 'tape measures' for a voltage-gated K+ channel

31 March 2020

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Molecular architecture of the KvAP voltage-dependent K+ channel in a lipid bilayer

31 March 2020

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Gating currents from a nonconducting mutant reveal open-closed conformations in Shaker K+ channels

31 March 2020

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A simple method for displaying the hydropathic character of a protein

31 March 2020

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Principles of Fluorescence Spectroscopy

31 March 2020

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Identifiers

DOI

10.1038/NRN1559

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11 August 2017

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