Nutlin-3 induces apoptosis, disrupts viral latency and inhibits expression of angiopoietin-2 in Kaposi sarcoma tumor cells. (Q35954902)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22421142%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

Nutlin-3 induces apoptosis, disrupts viral latency and inhibits expression of angiopoietin-2 in Kaposi sarcoma tumor cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22421142%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

5

1 reference

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26 January 2020

author name string

Fengchun Ye

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22421142%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Ali Abdul Lattif

2

1 reference

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26 January 2020

Jianping Xie

3

1 reference

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26 January 2020

Aaron Weinberg

4

1 reference

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26 January 2020

publication date

1 April 2012

1 reference

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26 January 2020

1 reference

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26 January 2020

volume

11

1 reference

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26 January 2020

issue

7

1 reference

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26 January 2020

page(s)

1393-1399

1 reference

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Recent advances in p53 research and cancer treatment

26 January 2020

cites work

1 reference

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2 October 2017

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Rapamycin blocks production of KSHV/HHV8: insights into the anti-tumor activity of an immunosuppressant drug

2 October 2017

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Paradoxical suppression of cellular senescence by p53

2 October 2017

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Rapamycin decelerates cellular senescence

2 October 2017

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Kaposi's sarcoma and mTOR: a crossroad between viral infection neoangiogenesis and immunosuppression

2 October 2017

1 reference

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Kaposi's sarcoma: a model of both malignancy and chronic inflammation

2 October 2017

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Reactivation of the p53 pathway as a treatment modality for KSHV-induced lymphomas.

2 October 2017

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Akt/TSC/mTOR activation by the KSHV G protein-coupled receptor: emerging insights into the molecular oncogenesis and treatment of Kaposi's sarcoma

2 October 2017

1 reference

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Kaposi's sarcoma-associated herpesvirus promotes angiogenesis by inducing angiopoietin-2 expression via AP-1 and Ets1

2 October 2017

1 reference

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Nutlin3 blocks vascular endothelial growth factor induction by preventing the interaction between hypoxia inducible factor 1alpha and Hdm2.

2 October 2017

1 reference

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Functional p53 signaling in Kaposi's sarcoma-associated herpesvirus lymphomas: implications for therapy.

2 October 2017

1 reference

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Kaposi's sarcoma-associated herpesvirus-encoded latency-associated nuclear antigen induces chromosomal instability through inhibition of p53 function

2 October 2017

1 reference

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Sirolimus for Kaposi's sarcoma in renal-transplant recipients

2 October 2017

1 reference

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Dynamics in the p53-Mdm2 ubiquitination pathway

2 October 2017

1 reference

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In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350880

Hypoxia-inducible factor-1 mediates activation of cultured vascular endothelial cells by inducing multiple angiogenic factors

2 October 2017

1 reference

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Biology of Kaposi's sarcoma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350880

Expression of angiopoietin-2 by human endometrial endothelial cells: regulation by hypoxia and inflammation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350880

p53 inhibition by the LANA protein of KSHV protects against cell death

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350880

Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350880

TP53 and MTOR crosstalk to regulate cellular senescence

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350880

p53: Pro-aging or pro-longevity?

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350880

The choice between p53-induced senescence and quiescence is determined in part by the mTOR pathway

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350880

Mdm2: keeping p53 under control

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350880

TP53 codon 72 polymorphism in classic, endemic and epidemic Kaposi's sarcoma in African and Caucasian patients

11 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.4161%2FCC.19756

Angiopoietin-2 sensitizes endothelial cells to TNF-alpha and has a crucial role in the induction of inflammation

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.4161%2FCC.19756

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/22421142

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4161/CC.19756

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22421142%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22421142%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22421142%20AND%20SRC:MED&resulttype=core&format=json