Sin3: a flexible regulator of global gene expression and genome stability. (Q35964130)

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5 January 2020

review article

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title

Sin3: a flexible regulator of global gene expression and genome stability (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15565322%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

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Gene Ontology release 2020-05-02

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2

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5 January 2020

author name string

Rebecca A Silverstein

series ordinal

1

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publication date

23 November 2004

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5 January 2020

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volume

47

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5 January 2020

page(s)

1-17

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issue

1

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https://scigraph.springernature.com/pub.10.1007/s00294-004-0541-5

5 January 2020

exact match

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cites work

p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage

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https://api.crossref.org/works/10.1007%2FS00294-004-0541-5

The p55 subunit of Drosophila chromatin assembly factor 1 is homologous to a histone deacetylase-associated protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00294-004-0541-5

RPD1 (SIN3/UME4) is required for maximal activation and repression of diverse yeast genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00294-004-0541-5

Transcriptional repression in Saccharomyces cerevisiae by a SIN3-LexA fusion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00294-004-0541-5

The Saccharomyces cerevisiae SIN3 gene, a negative regulator of HO, contains four paired amphipathic helix motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00294-004-0541-5

Genome-wide binding map of the histone deacetylase Rpd3 in yeast

21 January 2018

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12 December 2020

Loss of Sin3/Rpd3 histone deacetylase restores the DNA damage response in checkpoint-deficient strains of Saccharomyces cerevisiae

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12 December 2020

The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription

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12 December 2020

Nucleosomal DNA regulates the core-histone-binding subunit of the human Hat1 acetyltransferase

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12 December 2020

Requirement of Hos2 histone deacetylase for gene activity in yeast

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12 December 2020

The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities

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12 December 2020

Transcriptional regulation by the retinoblastoma protein

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12 December 2020

Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase

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12 December 2020

Molecular determinants of the interaction of Mad with the PAH2 domain of mSin3.

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12 December 2020

The negative regulator Opi1 of phospholipid biosynthesis in yeast contacts the pleiotropic repressor Sin3 and the transcriptional activator Ino2.

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12 December 2020

Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.

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12 December 2020

Functional and physical interaction between the histone methyl transferase Suv39H1 and histone deacetylases

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12 December 2020

The corepressor mSin3A regulates phosphorylation-induced activation, intranuclear location, and stability of AML1.

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12 December 2020

HERP, a novel heterodimer partner of HES/E(spl) in Notch signaling

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12 December 2020

SMRTER, a Drosophila nuclear receptor coregulator, reveals that EcR-mediated repression is critical for development.

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12 December 2020

The co-repressor mSin3A is a functional component of the REST-CoREST repressor complex

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12 December 2020

Coactivator and corepressor complexes in nuclear receptor function

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12 December 2020

Extension of the binding motif of the Sin3 interacting domain of the Mad family proteins

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12 December 2020

Role of the Sin3-histone deacetylase complex in growth regulation by the candidate tumor suppressor p33(ING1).

1 reference

12 December 2020

Identification and characterization of three new components of the mSin3A corepressor complex

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12 December 2020

Alp13, an MRG family protein, is a component of fission yeast Clr6 histone deacetylase required for genomic integrity

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12 December 2020

Temporal recruitment of the mSin3A-histone deacetylase corepressor complex to the ETS domain transcription factor Elk-1.

1 reference

12 December 2020

A widely distributed putative mammalian transcriptional regulator containing multiple paired amphipathic helices, with similarity to yeast SIN3

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12 December 2020

Nucleosome assembly by a complex of CAF-1 and acetylated histones H3/H4

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12 December 2020

Pf1, a novel PHD zinc finger protein that links the TLE corepressor to the mSin3A-histone deacetylase complex

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12 December 2020

New roles for the RB tumor suppressor protein

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12 December 2020

The Rpd3-Sin3 histone deacetylase regulates replication timing and enables intra-S origin control in Saccharomyces cerevisiae

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12 December 2020

A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p

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12 December 2020

Silenced chromatin is permissive to activator binding and PIC recruitment

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12 December 2020

Targeted recruitment of the Sin3-Rpd3 histone deacetylase complex generates a highly localized domain of repressed chromatin in vivo

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12 December 2020

Roles for the Saccharomyces cerevisiae SDS3, CBK1 and HYM1 genes in transcriptional repression by SIN3.

1 reference

12 December 2020

The major cytoplasmic histone acetyltransferase in yeast: links to chromatin replication and histone metabolism

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12 December 2020

Recruitment of O-GlcNAc transferase to promoters by corepressor mSin3A: coupling protein O-GlcNAcylation to transcriptional repression

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12 December 2020

RBP1 recruits the mSIN3-histone deacetylase complex to the pocket of retinoblastoma tumor suppressor family proteins found in limited discrete regions of the nucleus at growth arrest

1 reference

12 December 2020

Both positive and negative regulators of HO transcription are required for mother-cell-specific mating-type switching in yeast

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12 December 2020

RNA polymerase II is a glycoprotein. Modification of the COOH-terminal domain by O-GlcNAc

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12 December 2020

The highly conserved region of the co-repressor Sin3A functionally interacts with the co-repressor Alien

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12 December 2020

The corepressor N-CoR and its variants RIP13a and RIP13Delta1 directly interact with the basal transcription factors TFIIB, TAFII32 and TAFII70.

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12 December 2020

Specific targeting and constitutive association of histone deacetylase complexes during transcriptional repression

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12 December 2020

mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression

1 reference

12 December 2020

Temporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesis

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12 December 2020

Saccharomyces cerevisiae Sin3p facilitates DNA double-strand break repair

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12 December 2020

DNA damage-inducible gene p33ING2 negatively regulates cell proliferation through acetylation of p53

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12 December 2020

Stoichiometric and steric principles governing repression by nuclear hormone receptors

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12 December 2020

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

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12 December 2020

The Max network gone mad.

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12 December 2020

MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex

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12 December 2020

An amino-terminal domain of Mxi1 mediates anti-Myc oncogenic activity and interacts with a homolog of the yeast transcriptional repressor SIN3

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12 December 2020

Ultraviolet radiation sensitivity and reduction of telomeric silencing in Saccharomyces cerevisiae cells lacking chromatin assembly factor-I.

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12 December 2020

A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression

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12 December 2020

ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation

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12 December 2020

SAP30, a component of the mSin3 corepressor complex involved in N-CoR-mediated repression by specific transcription factors

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12 December 2020

Signal-specific co-activator domain requirements for Pit-1 activation

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12 December 2020

Sds3 (suppressor of defective silencing 3) is an integral component of the yeast Sin3[middle dot]Rpd3 histone deacetylase complex and is required for histone deacetylase activity.

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12 December 2020

Ordered recruitment of transcription and chromatin remodeling factors to a cell cycle- and developmentally regulated promoter.

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12 December 2020

Identification of mammalian Sds3 as an integral component of the Sin3/histone deacetylase corepressor complex

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12 December 2020

Histone deacetylase activity is required for full transcriptional repression by mSin3A

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12 December 2020

Sin3 corepressor function in Myc-induced transcription and transformation

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12 December 2020

Repression by Ume6 involves recruitment of a complex containing Sin3 corepressor and Rpd3 histone deacetylase to target promoters

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12 December 2020

The C. elegans MDL-1 and MXL-1 proteins can functionally substitute for vertebrate MAD and MAX

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12 December 2020

The SIN3/RPD3 deacetylase complex is essential for G(2) phase cell cycle progression and regulation of SMRTER corepressor levels

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12 December 2020

Evidence that the transcriptional regulators SIN3 and RPD3, and a novel gene (SDS3) with similar functions, are involved in transcriptional silencing in S. cerevisiae.

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12 December 2020

The corepressor mSin3a interacts with the proline-rich domain of p53 and protects p53 from proteasome-mediated degradation

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12 December 2020

mSin3-associated protein, mSds3, is essential for pericentric heterochromatin formation and chromosome segregation in mammalian cells

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12 December 2020

In vitro regulation of a SIN3-dependent DNA-binding activity by stimulatory and inhibitory factors

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12 December 2020

A new role for the transcriptional corepressor SIN3; regulation of centromeres.

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12 December 2020

Activation of the yeast HO gene by release from multiple negative controls

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12 December 2020

Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression

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12 December 2020

A mechanism of repression by acute myeloid leukemia-1, the target of multiple chromosomal translocations in acute leukemia

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12 December 2020

The SIN3 deacetylase complex represses genes encoding mitochondrial proteins: implications for the regulation of energy metabolism

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12 December 2020

The GAGA factor of Drosophila interacts with SAP18, a Sin3-associated polypeptide

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12 December 2020

Signaling disrupts mSin3A binding to the Mad1-like Sin3-interacting domain of TIEG2, an Sp1-like repressor

1 reference

12 December 2020

TIS7 interacts with the mammalian SIN3 histone deacetylase complex in epithelial cells.

1 reference

12 December 2020

Identification of the Sin3-binding site in Ume6 defines a two-step process for conversion of Ume6 from a transcriptional repressor to an activator in yeast

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12 December 2020

Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression

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12 December 2020

DNA damage activates p53 through a phosphorylation-acetylation cascade

1 reference

12 December 2020

Direct selection for mutants with increased K+ transport in Saccharomyces cerevisiae

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12 December 2020

The Saccharomyces cerevisiae GAM2/SIN3 protein plays a role in both activation and repression of transcription

1 reference

12 December 2020

Dual retinoblastoma-binding proteins with properties related to a negative regulator of ras in yeast

1 reference

12 December 2020

Identification of the Saccharomyces cerevisiae genes STB1-STB5 encoding Sin3p binding proteins

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12 December 2020

Mnt, a novel Max-interacting protein is coexpressed with Myc in proliferating cells and mediates repression at Myc binding sites.

1 reference

12 December 2020

A 13-amino acid amphipathic alpha-helix is required for the functional interaction between the transcriptional repressor Mad1 and mSin3A

1 reference

12 December 2020

The MAPK Hog1 recruits Rpd3 histone deacetylase to activate osmoresponsive genes.

1 reference

12 December 2020

Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3

1 reference

12 December 2020

Mapping global histone acetylation patterns to gene expression

1 reference

12 December 2020

A retinoblastoma-binding protein related to a negative regulator of Ras in yeast

1 reference

12 December 2020

Identification of negative regulatory genes that govern the expression of early meiotic genes in yeast

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12 December 2020

Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin remodeling complexes

1 reference

12 December 2020

Bipartite structure of an early meiotic upstream activation sequence from Saccharomyces cerevisiae

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12 December 2020

Histone H3-K9 methyltransferase ESET is essential for early development

1 reference

12 December 2020

A multiple subunit Mi-2 histone deacetylase from Xenopus laevis cofractionates with an associated Snf2 superfamily ATPase

1 reference

12 December 2020

Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex

1 reference

12 December 2020

Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1

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12 December 2020

Role for the mortality factors MORF4, MRGX, and MRG15 in transcriptional repression via associations with Pf1, mSin3A, and Transducin-Like Enhancer of Split

1 reference

12 December 2020

SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins

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12 December 2020

Genomewide studies of histone deacetylase function in yeast

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12 December 2020

Drosophila NURF-55, a WD repeat protein involved in histone metabolism

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12 December 2020

The LAZ3(BCL-6) oncoprotein recruits a SMRT/mSIN3A/histone deacetylase containing complex to mediate transcriptional repression.

1 reference

12 December 2020

Components of the SMRT corepressor complex exhibit distinctive interactions with the POZ domain oncoproteins PLZF, PLZF-RARalpha, and BCL-6

1 reference

12 December 2020

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

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12 December 2020

SIN3-dependent transcriptional repression by interaction with the Mad1 DNA-binding protein

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12 December 2020

A new member of the Sin3 family of corepressors is essential for cell viability and required for retroelement propagation in fission yeast

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12 December 2020

Cell growth inhibition by the Mad/Max complex through recruitment of histone deacetylase activity

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12 December 2020

A conserved alpha-helical motif mediates the interaction of Sp1-like transcriptional repressors with the corepressor mSin3A

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12 December 2020

The coregulator exchange in transcriptional functions of nuclear receptors

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12 December 2020

Transcriptional repression by UME6 involves deacetylation of lysine 5 of histone H4 by RPD3.

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12 December 2020

Components of a pathway maintaining histone modification and heterochromatin protein 1 binding at the pericentric heterochromatin in Mammalian cells

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12 December 2020

The winged-helix/forkhead protein myocyte nuclear factor beta (MNF-beta) forms a co-repressor complex with mammalian sin3B

1 reference

12 December 2020

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

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12 December 2020

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12 December 2020

Cell cycle-regulated histone acetylation required for expression of the yeast HO gene

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12 December 2020

SMRT isoforms mediate repression and anti-repression of nuclear receptor heterodimers

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12 December 2020

The ancient regulatory-protein family of WD-repeat proteins

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12 December 2020

ING1 represses transcription by direct DNA binding and through effects on p53

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12 December 2020

Transcriptional repression by neuron-restrictive silencer factor is mediated via the Sin3-histone deacetylase complex

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12 December 2020