Differential sensitivity of glioma- versus lung cancer-specific EGFR mutations to EGFR kinase inhibitors (Q35967385)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22588883%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

title

Differential sensitivity of glioma- versus lung cancer-specific EGFR mutations to EGFR kinase inhibitors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22588883%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22588883%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Igor Vivanco

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22588883%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Carl Campos

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22588883%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Christian Grommes

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22588883%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Linda Liau

19

1 reference

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1 February 2020

Lisa M DeAngelis

33

1 reference

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1 February 2020

Minesh Mehta

37

1 reference

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1 February 2020

Ingo K Mellinghoff

39

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22588883%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

25

Patrick Y Wen

1 reference

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1 February 2020

38

Timothy F Cloughesy

1 reference

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1 February 2020

30

Steve Horvath

1 reference

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1 February 2020

author name string

H Ian Robins

2

1 reference

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1 February 2020

Daniel Rohle

3

1 reference

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1 February 2020

Phioanh Leia Nghiemphu

6

1 reference

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1 February 2020

Sara Kubek

7

1 reference

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1 February 2020

Barbara Oldrini

8

1 reference

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1 February 2020

Milan G Chheda

9

1 reference

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1 February 2020

Nicolas Yannuzzi

10

1 reference

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1 February 2020

Hui Tao

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22588883%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Shaojun Zhu

12

1 reference

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1 February 2020

Akio Iwanami

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22588883%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Daisuke Kuga

14

1 reference

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1 February 2020

Julie Dang

15

1 reference

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1 February 2020

Alicia Pedraza

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22588883%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Adriana Heguy

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22588883%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Frank Lieberman

20

1 reference

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1 February 2020

W K Alfred Yung

21

1 reference

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1 February 2020

Mark R Gilbert

22

1 reference

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1 February 2020

Jan Drappatz

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22588883%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Kathleen R Lamborn

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22588883%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Susan M Chang

27

1 reference

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1 February 2020

Michael D Prados

28

1 reference

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1 February 2020

Howard A Fine

29

1 reference

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1 February 2020

Nian Wu

31

1 reference

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1 February 2020

Andrew B Lassman

32

1 reference

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1 February 2020

William H Yong

34

1 reference

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1 February 2020

John G Kuhn

35

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22588883%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Paul S Mischel

36

1 reference

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1 February 2020

David A Reardon

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22588883%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

publication date

31 March 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22588883%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22588883%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

volume

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22588883%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22588883%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

page(s)

458-471

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22588883%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

1 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3354723/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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2 October 2017

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2 October 2017

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2 October 2017

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The phosphatase and tensin homolog regulates epidermal growth factor receptor (EGFR) inhibitor response by targeting EGFR for degradation

2 October 2017

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Structural and mechanistic underpinnings of the differential drug sensitivity of EGFR mutations in non-small cell lung cancer

2 October 2017

1 reference

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A phase I and pharmacokinetic study of oral lapatinib administered once or twice daily in patients with solid malignancies

2 October 2017

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A phase I study of a 2-day lapatinib chemosensitization pulse preceding nanoparticle albumin-bound Paclitaxel for advanced solid malignancies

2 October 2017

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Transient potent BCR-ABL inhibition is sufficient to commit chronic myeloid leukemia cells irreversibly to apoptosis

2 October 2017

1 reference

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Comprehensive genomic characterization defines human glioblastoma genes and core pathways

2 October 2017

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An integrated genomic analysis of human glioblastoma multiforme

2 October 2017

1 reference

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Malignant gliomas in adults

2 October 2017

1 reference

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Survival of cancer cells is maintained by EGFR independent of its kinase activity

2 October 2017

1 reference

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EGFR antagonists in cancer treatment

2 October 2017

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Epidermal growth factor receptor inhibitors in neuro-oncology: hopes and disappointments

2 October 2017

1 reference

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The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP

2 October 2017

1 reference

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Impact of common epidermal growth factor receptor and HER2 variants on receptor activity and inhibition by lapatinib

2 October 2017

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A quantitative analysis of kinase inhibitor selectivity

2 October 2017

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Malignant astrocytic glioma: genetics, biology, and paths to treatment

2 October 2017

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Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies

2 October 2017

1 reference

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Epidermal growth factor receptor mutations in lung cancer

2 October 2017

1 reference

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Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain

2 October 2017

1 reference

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Kinetic analysis of epidermal growth factor receptor somatic mutant proteins shows increased sensitivity to the epidermal growth factor receptor tyrosine kinase inhibitor, erlotinib

2 October 2017

1 reference

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Oncogenic transformation by inhibitor-sensitive and -resistant EGFR mutants

2 October 2017

1 reference

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ERBB receptors and cancer: the complexity of targeted inhibitors

2 October 2017

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A unique structure for epidermal growth factor receptor bound to GW572016 (Lapatinib): relationships among protein conformation, inhibitor off-rate, and receptor activity in tumor cells

2 October 2017

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EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib

2 October 2017

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Antitumor activity of HKI-272, an orally active, irreversible inhibitor of the HER-2 tyrosine kinase

2 October 2017

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EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

2 October 2017

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Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

2 October 2017

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2 October 2017

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2 October 2017

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The characterization of novel, dual ErbB-2/EGFR, tyrosine kinase inhibitors: potential therapy for cancer

2 October 2017

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Untangling the ErbB signalling network

2 October 2017

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Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor

2 October 2017

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2 October 2017

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Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells

2 October 2017

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11 July 2018

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Shifting paradigms: the seeds of oncogene addiction

11 July 2018

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A phase I/II trial of GW572016 (lapatinib) in recurrent glioblastoma multiforme: clinical outcomes, pharmacokinetics and molecular correlation.

24 September 2018

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24 September 2018

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Formation of intracranial tumors by genetically modified human astrocytes defines four pathways critical in the development of human anaplastic astrocytoma

24 September 2018

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Epidermal growth factor ligand-independent, unregulated, cell-transforming potential of a naturally occurring human mutant EGFRvIII gene.

24 September 2018

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1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22588883

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

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1 reference

PubMed

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inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/2159-8290.CD-11-0284

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22588883%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22588883%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1 reference