Metabolism of the bioreductive cytotoxin SR 4233 by tumour cells: enzymatic studies (Q35975685)

11 August 2017

Metabolism of the bioreductive cytotoxin SR 4233 by tumour cells: enzymatic studies (English)

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11 August 2017

J Wang

1

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11 August 2017

K A Biedermann

series ordinal

2

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11 August 2017

C R Wolf

series ordinal

3

1 reference

11 August 2017

J M Brown

series ordinal

4

1 reference

11 August 2017

language of work or name

English

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publication date

1 February 1993

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British Journal of Cancer

11 August 2017

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11 August 2017

67

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11 August 2017

2

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11 August 2017

321-325

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Enhancement of CCNU cytotoxicity by misonidazole: possible therapeutic gain

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968170

Free radicals in pharmacology and toxicology--selected topics

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968170

Reductive drug metabolism.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968170

SR-4233: a new bioreductive agent with high selective toxicity for hypoxic mammalian cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968170

Potentiation by the hypoxic cytotoxin SR 4233 of cell killing produced by fractionated irradiation of mouse tumors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968170

SR 4233 cytotoxicity and metabolism in DNA repair-competent and repair-deficient cell cultures

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968170

DT-diaphorase and cancer chemotherapy

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968170

A general mechanism for microsomal activation of quinone anticancer agents to free radicals

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968170

Metabolism of SR 4233 by Chinese hamster ovary cells: basis of selective hypoxic cytotoxicity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968170

Reductive metabolism of 3-amino-1,2,4-benzotriazine-1,4-dioxide (SR 4233) and the induction of unscheduled DNA synthesis in rat and human derived cell lines

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968170

A fluorometric method for measuring ethoxycoumarin O-deethylase activity by reversed-phase high performance liquid chromatography

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968170

Repair of DNA and chromosome breaks in cells exposed to SR 4233 under hypoxia or to ionizing radiation.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968170

Nitroreductase activity of mammalian liver aldehyde oxidase.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968170

In vitro hepatotoxicity of SR 4233 (3-amino-1,2,4-benzotriazine-1,4-dioxide), a hypoxic cytotoxin and potential antitumor agent.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968170

Enhancement of the antitumor effect of flavone acetic acid by the bioreductive cytotoxic drug SR 4233 in a murine carcinoma

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968170

A new method for simultaneous purification of cytochrome b5 and NADPH-cytochrome c reductase from rat liver microsomes

24 September 2018

1 reference

12 December 2020

A new highly sensitive assay for ethoxycoumarin deethylase in cultured hepatocytes

1 reference

12 December 2020

Isolation of a high spin form of cytochrome P-450 induced in rat liver by 3-methylcholanthrene

1 reference

12 December 2020

Adaptation of the bicinchoninic acid protein assay for use with microtiter plates and sucrose gradient fractions

1 reference

12 December 2020

Molecular mechanisms for the hypoxia-dependent activation of 3-amino-1,2,4-benzotriazine-1,4-dioxide (SR 4233)

1 reference

12 December 2020

Enhancement of radiation-induced tumor cell killing by the hypoxic cell toxin SR 4233

1 reference

12 December 2020

Molecular enzymology of the reductive bioactivation of hypoxic cell cytotoxins

1 reference

12 December 2020

Enzymology of the reductive bioactivation of SR 4233. A novel benzotriazine di-N-oxide hypoxic cell cytotoxin

1 reference

12 December 2020

Microsomal reduction of 3-amino-1,2,4-benzotriazine 1,4-dioxide to a free radical

1 reference

12 December 2020

Identifiers

DOI

10.1038/BJC.1993.59

1 reference

Dimensions Publication ID

11 August 2017

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1 reference

11 August 2017

PubMed publication ID

8431360

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