Amyloid-β induces hepatic insulin resistance by activating JAK2/STAT3/SOCS-1 signaling pathway (Q35976702)

11 August 2017

Amyloid-β induces hepatic insulin resistance by activating JAK2/STAT3/SOCS-1 signaling pathway (English)

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11 August 2017

1 reference

2

Ben Zhou

1 reference

11 August 2017

Yi Zhang

1

1 reference

11 August 2017

Fang Zhang

3

1 reference

11 August 2017

Jingxia Wu

4

1 reference

11 August 2017

Yanan Hu

5

1 reference

11 August 2017

Yang Liu

6

1 reference

11 August 2017

Qiwei Zhai

7

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11 August 2017

language of work or name

English

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publication date

20 April 2012

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11 August 2017

10

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inferred from page(s)

published in

Diabetes

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11 August 2017

61

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11 August 2017

6

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11 August 2017

1434-1443

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

11 August 2017

start time

27 August 2021

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse

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Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms

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Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase

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CD36, a class B scavenger receptor, is expressed on microglia in Alzheimer's disease brains and can mediate production of reactive oxygen species in response to beta-amyloid fibrils

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2 October 2017

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2 October 2017

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11 July 2018

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24 September 2018

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24 September 2018

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Amyloid-beta causes memory impairment by disturbing the JAK2/STAT3 axis in hippocampal neurons.

24 September 2018

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24 September 2018

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24 September 2018

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Hydrogen peroxide stimulates tetrahydrobiopterin synthesis through activation of the Jak2 tyrosine kinase pathway in vascular endothelial cells

24 September 2018

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Intake of sucrose-sweetened water induces insulin resistance and exacerbates memory deficits and amyloidosis in a transgenic mouse model of Alzheimer disease.

24 September 2018

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Soluble Abeta inhibits specific signal transduction cascades common to the insulin receptor pathway.

24 September 2018

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Elevated plasma triglyceride levels precede amyloid deposition in Alzheimer's disease mouse models with abundant A beta in plasma.

24 September 2018

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24 September 2018

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Plasma Abeta42 correlates positively with increased body fat in healthy individuals.

24 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357286

Plasma levels of amyloid beta-protein 42 are increased in women with mild cognitive impairment.

24 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357286

Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease

24 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357286

Increased risk of type 2 diabetes in Alzheimer disease

24 September 2018

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Age but not diagnosis is the main predictor of plasma amyloid beta-protein levels.

24 September 2018

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RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain

24 September 2018

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Plaque-associated disruption of CSF and plasma amyloid-beta (Abeta) equilibrium in a mouse model of Alzheimer's disease.

24 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357286

Distribution and fluidizing action of soluble and aggregated amyloid beta-peptide in rat synaptic plasma membranes.

24 September 2018

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Intravenous glucose tolerance test-derived insulin sensitivity changes during the menstrual cycle

24 September 2018

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PubMed

12 December 2020

Longitudinal observation on CSF Abeta42 levels in young to middle-aged amyloid precursor protein/presenilin-1 doubly transgenic mice

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PubMed

12 December 2020

Amyloid beta oligomers induce impairment of neuronal insulin receptors

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PubMed

12 December 2020

Identifiers

DOI

10.2337/DB11-0499

1 reference

11 August 2017

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11 August 2017

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