Formation and loss of O6-methyldeoxyguanosine in human leucocyte DNA following sequential DTIC and fotemustine chemotherapy. (Q35978464)

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26 October 2019

title

Formation and loss of O6-methyldeoxyguanosine in human leucocyte DNA following sequential DTIC and fotemustine chemotherapy (English)

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26 October 2019

1 reference

1

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26 October 2019

author name string

G P Margison

2

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26 October 2019

N Thatcher

3

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26 October 2019

P J O'Connor

4

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26 October 2019

D P Cooper

5

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26 October 2019

language of work or name

English

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publication date

1 May 1994

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British Journal of Cancer

26 October 2019

published in

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26 October 2019

volume

69

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26 October 2019

issue

5

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26 October 2019

page(s)

853-857

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Complementation of sensitivity to alkylating agents in Escherichia coli and Chinese hamster ovary cells by expression of a cloned bacterial DNA repair gene

26 October 2019

cites work

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Suppression of human DNA alkylation-repair defects by Escherichia coli DNA-repair genes

2 October 2017

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Importance of the DNA repair enzyme O6-alkyl guanine alkyltransferase (AT) in cancer chemotherapy.

2 October 2017

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Mammalian O6-alkylguanine-DNA alkyltransferase: regulation and importance in response to alkylating carcinogenic and therapeutic agents

2 October 2017

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Induction and time course of DNA single-strand breaks in lymphocytes from patients treated with dacarbazine

2 October 2017

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Determination of N7-methylguanine in DNA of white blood cells from cancer patients treated with dacarbazine

2 October 2017

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Promutagenic methylation damage in bladder DNA from patients with bladder cancer associated with schistosomiasis and from normal individuals

2 October 2017

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Interaction of the carcinogen 3,3-dimethyl-1-phenyltriazene with nucleic acids of various rat tissues and the effect of a protein-free diet

2 October 2017

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DTIC (NSC-45388) in malignant melanoma: a perspective

2 October 2017

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Dosage and cycle effects of dacarbazine (DTIC) and fotemustine on O6-alkylguanine-DNA alkyltransferase in human peripheral blood mononuclear cells.

2 October 2017

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In vivo metabolism and reaction with DNA of the cytostatic agent, 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide (DTIC).

27 July 2018

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Cytotoxicity of 5-(3-methyl-1-triazeno)imidazole-4-carboxamide (MTIC) on Mer+, Mer+Rem- and Mer- cell lines: differential potentiation by 3-acetamidobenzamide

27 July 2018

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Transfection of murine multi-potent haemopoietic stem cells with an E. coli DNA alkyltransferase gene confers resistance to the toxic effects of alkylating agents.

27 July 2018

1 reference

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Accumulation of O6-methylguanine in human blood leukocyte DNA during exposure to procarbazine and its relationships with dose and repair.

27 July 2018

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The detection of alkylation damage in the DNA of human gastrointestinal tissues

27 July 2018

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O6-alkylguanine-DNA alkyltransferase depletion and regeneration in human peripheral lymphocytes following dacarbazine and fotemustine

27 July 2018

1 reference

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Transfection and expression of human O6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: the role of MGMT in protection against the genotoxic effects of alkylating agents

27 July 2018

1 reference

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Comparison of virus reactivation, DNA base damage, and cell cycle effects in autologous human melanoma cells resistant to methylating agents

27 July 2018

1 reference

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Radioimmunoassay of O6-methyldeoxyguanosine in DNA of cells alkylated in vitro and in vivo

24 September 2018

1 reference

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Differential cytotoxicity and DNA-damaging effects produced in human cells of the Mer+ and Mer- phenotypes by a series of 1-aryl-3-alkyltriazenes

24 September 2018

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In vitro and in vivo methazolastone-induced DNA damage and repair in L-1210 leukemia sensitive and resistant to chloroethylnitrosoureas.

24 September 2018

1 reference

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Expression in mammalian cells of a truncated Escherichia coli gene coding for O6-alkylguanine alkyltransferase reduces the toxic effects of alkylating agents.

24 September 2018

1 reference

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Antibodies against 7-methyldeoxyguanosine: its detection in rat peripheral blood lymphocyte DNA and potential applications to molecular epidemiology.

24 September 2018

1 reference

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Studies in gastric carcinogenesis. IV. O6-methylguanine and its repair in normal and atrophic biopsy specimens of human gastric mucosa. Correlation of O6-alkylguanine-DNA alkyltransferase activities in gastric mucosa and circulating lymphocytes.

24 September 2018

1 reference

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DNA methyl-adduct dosimetry and O6-alkylguanine-DNA alkyl transferase activity determinations in rat mammary carcinogenesis by procarbazine and N-methylnitrosourea.

24 September 2018

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24 September 2018

Identifiers

DOI

10.1038/BJC.1994.165

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8180013%20AND%20SRC:MED&resulttype=core&format=json

26 October 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8180013%20AND%20SRC:MED&resulttype=core&format=json

26 October 2019

PubMed publication ID

8180013

1 reference