PI3K/AKT signaling and systemic autoimmunity (Q35980515)

11 August 2017

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title

PI3K/AKT signaling and systemic autoimmunity (English)

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11 August 2017

Rahul K Patel

1

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11 August 2017

Chandra Mohan

series ordinal

2

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11 August 2017

publication date

1 January 2005

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11 August 2017

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11 August 2017

volume

31

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11 August 2017

issue

1

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11 August 2017

page(s)

47-55

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Immunosuppressive Effects of Dietary Wortmannin on Rats and Mice

11 August 2017

cites work

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12 December 2020

Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene

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12 December 2020

Tor signalling in bugs, brain and brawn

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12 December 2020

The role of PI3K in immune cells

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12 December 2020

Pten is essential for embryonic development and tumour suppression

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12 December 2020

Acute pathological effects on rats of orally administered wortmannin-containing preparations and purified wortmannin from Fusarium oxysporum

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12 December 2020

Early embryonic lethality in mice deficient in the p110beta catalytic subunit of PI 3-kinase

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12 December 2020

Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha

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12 December 2020

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

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12 December 2020

mTor is required for hypertrophy of Pten-deficient neuronal soma in vivo

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12 December 2020

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12 December 2020

PI3K in lymphocyte development, differentiation and activation

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12 December 2020

Activated Akt promotes increased resting T cell size, CD28-independent T cell growth, and development of autoimmunity and lymphoma

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12 December 2020

Constitutively active protein kinase B enhances Lck and Erk activities and influences thymocyte selection and activation

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12 December 2020

Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation

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12 December 2020

Human ltk: gene structure and preferential expression in human leukemic cells.

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12 December 2020

Cellular survival: a play in three Akts

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12 December 2020

Phosphatidylinositol 3-kinase regulates the CD4/CD8 T cell differentiation ratio

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12 December 2020

T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance

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12 December 2020

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)

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12 December 2020

Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems

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12 December 2020

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

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12 December 2020

Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice

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12 December 2020

Physiological functions of Pten in mouse tissues

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12 December 2020

Impaired Fas response and autoimmunity in Pten+/- mice

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12 December 2020

Gain-of-function polymorphism in mouse and human Ltk: implications for the pathogenesis of systemic lupus erythematosus

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12 December 2020

PTEN: from pathology to biology

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12 December 2020

Increased phosphoinositide 3-kinase activity induces a lymphoproliferative disorder and contributes to tumor generation in vivo

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12 December 2020

Phosphoinositide 3-kinases: a conserved family of signal transducers

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12 December 2020

Loss of a single allele of SHIP exacerbates the immunopathology of Pten heterozygous mice

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12 December 2020

Expression of Active Protein Kinase B in T Cells Perturbs Both T and B Cell Homeostasis and Promotes Inflammation

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12 December 2020

Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase.

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12 December 2020

Wortmannin enhances activation of CPP32 (Caspase-3) induced by TNF or anti-Fas

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12 December 2020

Identification of a novel PTEN mutation (L139X) in a patient with Cowden disease and Sjögren's syndrome.

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12 December 2020

A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation

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12 December 2020

PI3K/Akt and apoptosis: size matters

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12 December 2020

Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice

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12 December 2020

Critical roles of Pten in B cell homeostasis and immunoglobulin class switch recombination.

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12 December 2020

The phosphoinositide 3-kinase pathway

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12 December 2020

Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha.

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12 December 2020

Proliferative defect and embryonic lethality in mice homozygous for a deletion in the p110alpha subunit of phosphoinositide 3-kinase

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12 December 2020

The ltk receptor tyrosine kinase is expressed in pre-B lymphocytes and cerebral neurons and uses a non-AUG translational initiator

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12 December 2020

Pten inactivation alters peripheral B lymphocyte fate and reconstitutes CD19 function

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12 December 2020

Tumor induction by an Lck-MyrAkt transgene is delayed by mechanisms controlling the size of the thymus

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12 December 2020

Commitment to the CD4 lineage mediated by extracellular signal-related kinase mitogen-activated protein kinase and lck signaling

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12 December 2020

Akt/protein kinase B promotes organ growth in transgenic mice

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12 December 2020

Identifiers

DOI

10.1385/IR:31:1:47

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Dimensions Publication ID

11 August 2017

1036583376

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