HIV-1 and the hijacking of dendritic cells: a tug of war. (Q35988809)

11 August 2017

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title

HIV-1 and the hijacking of dendritic cells: a tug of war. (English)

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11 August 2017

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Marie Larsson

1

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publication date

1 January 2005

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Seminars in Immunopathology

11 August 2017

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11 August 2017

26

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11 August 2017

309-328

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11 August 2017

3

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https://scigraph.springernature.com/pub.10.1007/s00281-004-0178-y

11 August 2017

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cites work

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Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120.

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Dysfunction and infection of freshly isolated blood myeloid and plasmacytoid dendritic cells in patients infected with HIV-1

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Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome

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The susceptibility to X4 and R5 human immunodeficiency virus-1 strains of dendritic cells derived in vitro from CD34(+) hematopoietic progenitor cells is primarily determined by their maturation stage

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Apoptosis enhancement by the HIV-1 Nef protein.

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12 December 2020

Decreased CD40 ligand induction in CD4 T cells and dysregulated IL-12 production during HIV infection.

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12 December 2020

DC-SIGN, a C-type lectin on dendritic cells that unveils many aspects of dendritic cell biology

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12 December 2020

Dendritic cells transduced with HIV Nef express normal levels of HLA-A and HLA-B class I molecules

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12 December 2020

Human immunodeficiency virus type 1 Nef mediates activation of STAT3 in immature dendritic cells

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12 December 2020

HIV Nef inhibits T cell migration.

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12 December 2020

Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria

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12 December 2020

Langerhans cells and the cells of Langerhans cell histiocytosis do not express DC-SIGN

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12 December 2020

From synapses to immunological memory: the role of sustained T cell stimulation

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12 December 2020

Functional gene transfer of HIV DNA by an HIV receptor-independent mechanism

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Macrophage-tropic variants initiate human immunodeficiency virus type 1 infection after sexual, parenteral, and vertical transmission

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HIV-1 Tat represses transcription from the mannose receptor promoter

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12 December 2020

The immunological synapse: a molecular machine controlling T cell activation

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12 December 2020

HIV-1 Nef induces dendritic cell differentiation: a possible mechanism of uninfected CD4(+) T cell activation.

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12 December 2020

HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages

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12 December 2020

The functional consequences of delivery of HIV-1 Nef to dendritic cells using an adenoviral vector.

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12 December 2020

Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus

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12 December 2020

Loss of blood CD11c(+) myeloid and CD11c(-) plasmacytoid dendritic cells in patients with HIV-1 infection correlates with HIV-1 RNA virus load

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12 December 2020

Peripheral blood Dendritic cells are not a major reservoir for HIV type 1 in infected individuals on virally suppressive HAART.

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12 December 2020

Langerhans cell as primary target and vehicle for transmission of HIV

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12 December 2020

Dendritic cell chemotaxis and transendothelial migration are induced by distinct chemokines and are regulated on maturation

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12 December 2020

HIV-1 induces cytotoxic T lymphocytes in the cervix of infected women

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12 December 2020

Fcgamma receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I-restricted antigen presentation after immune complex internalization

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12 December 2020

Selective recruitment of immature and mature dendritic cells by distinct chemokines expressed in different anatomic sites

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12 December 2020

MHC-I-restricted presentation of HIV-1 virion antigens without viral replication

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12 December 2020

HIV-1-infected dendritic cells up-regulate cell surface markers but fail to produce IL-12 p70 in response to CD40 ligand stimulation.

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12 December 2020

Active replication of HIV-1 at the lymphoepithelial surface of the tonsil

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12 December 2020

Presentation of exogenous whole inactivated simian immunodeficiency virus by mature dendritic cells induces CD4+ and CD8+ T-cell responses

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12 December 2020

Infectious and whole inactivated simian immunodeficiency viruses interact similarly with primate dendritic cells (DCs): differential intracellular fate of virions in mature and immature DCs

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12 December 2020

Interaction of mannose-binding lectin with HIV type 1 is sufficient for virus opsonization but not neutralization

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12 December 2020

Human immunodeficiency virus type 1 activates plasmacytoid dendritic cells and concomitantly induces the bystander maturation of myeloid dendritic cells

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12 December 2020

HIV-1 cell to cell transfer across an Env-induced, actin-dependent synapse

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12 December 2020

Dendritic cells exposed to human immunodeficiency virus type-1 transmit a vigorous cytopathic infection to CD4+ T cells

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12 December 2020

The RGD-containing domain of exogenous HIV-1 Tat inhibits the engulfment of apoptotic bodies by dendritic cells.

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12 December 2020

Susceptibility of human peripheral blood dendritic cells to infection by human immunodeficiency virus

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12 December 2020

Infection of dendritic cells with HIV1: virus load regulates stimulation and suppression of T-cell activity

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12 December 2020

HIV-1 integration in the human genome favors active genes and local hotspots

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12 December 2020

Natural alpha interferon-producing cells respond to human immunodeficiency virus type 1 with alpha interferon production and maturation into dendritic cells

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12 December 2020

Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses

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12 December 2020

A cytotoxic T lymphocyte inhibits acquired immunodeficiency syndrome virus replication in peripheral blood lymphocytes

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12 December 2020

Short Communication: Downregulation of Major Histocompatibility Class I on Human Dendritic Cells by HIV Nef Impairs Antigen Presentation to HIV-Specific CD8+ T Lymphocytes

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12 December 2020

HIV preferentially infects HIV-specific CD4+ T cells

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12 December 2020

Rapid infection of oral mucosal-associated lymphoid tissue with simian immunodeficiency virus

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12 December 2020

Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia

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12 December 2020

Increase in dendritic cell numbers, their function and the proportion uninfected during AZT therapy

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12 December 2020

Reduced blood CD123+ (lymphoid) and CD11c+ (myeloid) dendritic cell numbers in primary HIV-1 infection

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12 December 2020

HIV gp120 receptors on human dendritic cells.

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12 December 2020

Defective dendritic cell function in HIV-infected patients receiving effective highly active antiretroviral therapy: neutralization of IL-10 production and depletion of CD4+CD25+ T cells restore high levels of HIV-specific CD4+ T cell responses indu

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12 December 2020

Activation of HIV-1 specific CD4 and CD8 T cells by human dendritic cells: roles for cross-presentation and non-infectious HIV-1 virus

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12 December 2020

High levels of HIV-1 in plasma during all stages of infection determined by competitive PCR

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12 December 2020

Induction of anti-human immunodeficiency virus type 1 (HIV-1) CD8(+) and CD4(+) T-cell reactivity by dendritic cells loaded with HIV-1 X4-infected apoptotic cells

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12 December 2020

HIV-1 selection by epidermal dendritic cells during transmission across human skin

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12 December 2020

Genotypic and phenotypic characterization of HIV-1 patients with primary infection

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12 December 2020

Protective immunity induced by live attenuated simian immunodeficiency virus

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12 December 2020

Inactivated influenza virus, when presented on dendritic cells, elicits human CD8+ cytolytic T cell responses

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12 December 2020

Follicular dendritic cells retain HIV-1 particles on their plasma membrane, but are not productively infected in asymptomatic patients with follicular hyperplasia

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12 December 2020

Constitutive and induced expression of DC-SIGN on dendritic cell and macrophage subpopulations in situ and in vitro

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12 December 2020

Dendritic cells transfected with the nef genes of HIV-1 primary isolates specifically activate cytotoxic T lymphocytes from seropositive subjects

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12 December 2020

Enhanced dendritic cell-driven proliferation and anti-HIV activity of CD8(+) T cells by a new phenothiazine derivative, aminoperazine

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12 December 2020

DC-SIGN-mediated internalization of HIV is required for trans-enhancement of T cell infection

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12 December 2020

Mechanism(s) promoting HIV-1 infection of primary unstimulated T lymphocytes in autologous B cell/T cell co-cultures

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12 December 2020

Plasmacytoid dendritic cells are highly susceptible to human immunodeficiency virus type 1 infection and release infectious virus

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12 December 2020

Early highly active antiretroviral therapy for acute HIV-1 infection preserves immune function of CD8+ and CD4+ T lymphocytes

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12 December 2020

Differential transmission of human immunodeficiency virus type 1 by distinct subsets of effector dendritic cells

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12 December 2020

Sexual Transmission and Propagation of SIV and HIV in Resting and Activated CD4+ T Cells

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12 December 2020

Latent infection of epidermal Langerhans cells in HIV-positive individuals

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12 December 2020

Epidermal Langerhans cells--a target for HTLV-III/LAV infection.

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12 December 2020

HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation

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12 December 2020

Modulation of susceptibility to HIV-1 infection by the cytotoxic T lymphocyte antigen 4 costimulatory molecule.

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12 December 2020

Dendritic cells generated from blood monocytes of HIV-1 patients are not infected and act as competent antigen presenting cells eliciting potent T-cell responses

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12 December 2020

Productive infection of dendritic cells by HIV-1 and their ability to capture virus are mediated through separate pathways.

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12 December 2020

The T cell activation factor NF-ATc positively regulates HIV-1 replication and gene expression in T cells

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12 December 2020

Increased expression of the inflammatory chemokine CXC chemokine ligand 9/monokine induced by interferon-gamma in lymphoid tissues of rhesus macaques during simian immunodeficiency virus infection and acquired immunodeficiency syndrome

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12 December 2020

Dendritic cells cross-present HIV antigens from live as well as apoptotic infected CD4+ T lymphocytes.

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12 December 2020

The decreased replicative capacity of simian immunodeficiency virus SIVmac239Delta(nef) is manifest in cultures of immature dendritic cellsand T cells

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12 December 2020

Simian immunodeficiency virus dramatically alters expression of homeostatic chemokines and dendritic cell markers during infection in vivo.

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12 December 2020

Role of the HTLV-III/LAV envelope in syncytium formation and cytopathicity

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12 December 2020

Depletion in blood CD11c-positive dendritic cells from HIV-infected patients

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12 December 2020

Viral subversion of the immune system

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12 December 2020

DC-SIGN promotes exogenous MHC-I-restricted HIV-1 antigen presentation

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12 December 2020

Stimulatory and suppressive effects of infection of dendritic cells with HIV-1

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12 December 2020

Binding of Human Immunodeficiency Virus Type 1 to Immature Dendritic Cells Can Occur Independently of DC-SIGN and Mannose Binding C-Type Lectin Receptors via a Cholesterol-Dependent Pathway

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12 December 2020

Conjugates of dendritic cells and memory T lymphocytes from skin facilitate productive infection with HIV-1

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12 December 2020

Low levels of HIV-1 infection in cutaneous dendritic cells promote extensive viral replication upon binding to memory CD4+ T cells

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12 December 2020

Perspectives on the role of CD8+ cell suppressor factors and cytotoxic T lymphocytes during HIV infection.

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12 December 2020

Endocytosis of an HIV-derived lipopeptide into human dendritic cells followed by class I-restricted CD8(+) T lymphocyte activation

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12 December 2020

Cultured blood dendritic cells retain HIV-1 antigen-presenting capacity for memory CTL during progressive HIV-1 infection.

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12 December 2020

A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell.

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12 December 2020

Antigen-presentation by macrophages but not by dendritic cells in human immunodeficiency virus (HIV) infection

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12 December 2020

Differential infection of CD34+ cell-derived dendritic cells and monocytes with lymphocyte-tropic and monocyte-tropic HIV-1 strains

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12 December 2020

Dendritic cells acquire antigens from live cells for cross-presentation to CTL.

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12 December 2020

Both a precursor and a mature population of dendritic cells can bind HIV. However, only the mature population that expresses CD80 can pass infection to unstimulated CD4+ T cells

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12 December 2020

Cytokine signals are sufficient for HIV-1 infection of resting human T lymphocytes

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12 December 2020

HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell

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12 December 2020

Differential Impact of Late-Stage HIV-1 Infection on in Vitro and in Vivo Maturation of Myeloid Dendritic Cells

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12 December 2020

Pathogenesis of lentivirus infections

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12 December 2020

Immature dendritic cells selectively replicate macrophagetropic (M-tropic) human immunodeficiency virus type 1, while mature cells efficiently transmit both M- and T-tropic virus to T cells.

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12 December 2020

Endogenously expressed nef uncouples cytokine and chemokine production from membrane phenotypic maturation in dendritic cells

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12 December 2020

Role of complement in the control of HIV dynamics and pathogenesis

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12 December 2020

Cytokine expression by human peripheral blood dendritic cells stimulated in vitro with HIV-1 and herpes simplex virus

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12 December 2020

Inactivation of human immunodeficiency virus type 1 infectivity with preservation of conformational and functional integrity of virion surface proteins.

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12 December 2020

Recruitment of HIV and its receptors to dendritic cell-T cell junctions.

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12 December 2020

Decreased interferon-alpha production in HIV-infected patients correlates with numerical and functional deficiencies in circulating type 2 dendritic cell precursors

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12 December 2020

Infection frequency of dendritic cells and CD4+ T lymphocytes in spleens of human immunodeficiency virus-positive patients

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12 December 2020

Suppression of immune responses by dendritic cells infected with HIV.

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12 December 2020

Dendritic cell-T-cell interactions support coreceptor-independent human immunodeficiency virus type 1 transmission in the human genital tract

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12 December 2020

CD4 down modulation on T-cells: an 'immune' checkpoint for HIV.

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12 December 2020

The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore

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12 December 2020

Persistent decreases in blood plasmacytoid dendritic cell number and function despite effective highly active antiretroviral therapy and increased blood myeloid dendritic cells in HIV-infected individuals

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12 December 2020

Neutralization of the human immunodeficiency virus type 1 primary isolate JR-FL by human monoclonal antibodies correlates with antibody binding to the oligomeric form of the envelope glycoprotein complex

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12 December 2020

Acutely infected Langerhans cells are more efficient than T cells in disseminating HIV type 1 to activated T cells following a short cell-cell contact

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12 December 2020

Induction of CD4-dependent cell fusion by the HTLV-III/LAV envelope glycoprotein.

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12 December 2020

Human immunodeficiency virus type 1 neutralization is determined by epitope exposure on the gp120 oligomer

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12 December 2020

Compensatory link between fusion and endocytosis of human immunodeficiency virus type 1 in human CD4 T lymphocytes

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12 December 2020

CD8+ lymphocytes can control HIV infection in vitro by suppressing virus replication

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12 December 2020

Efficiency of cross presentation of vaccinia virus-derived antigens by human dendritic cells

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12 December 2020

Analysis of human immunodeficiency virus type 1 (HIV-1) variants and levels of infection in dendritic and T cells from symptomatic HIV-1-infected patients

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12 December 2020

The effect of in vitro human immunodeficiency virus infection on dendritic-cell differentiation and function

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12 December 2020

Candidate microbicides block HIV-1 infection of human immature Langerhans cells within epithelial tissue explants

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12 December 2020

New insights into host factors in HIV-1 pathogenesis

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12 December 2020

Selective transmission of R5-tropic HIV type 1 from dendritic cells to resting CD4+ T cells

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12 December 2020

Low levels of productive HIV infection in Langerhans cell-like dendritic cells differentiated in the presence of TGF-beta1 and increased viral replication with CD40 ligand-induced maturation

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12 December 2020

In vitro HIV1 infection of CD34+ progenitor-derived dendritic/Langerhans cells at different stages of their differentiation in the presence of GM-CSF/TNF alpha

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12 December 2020

Dichotomy between CD1a+ and CD83+ dendritic cells in lymph nodes during SIV infection of macaques.

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12 December 2020

Human CD4+ CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens

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12 December 2020

Cell-surface heparan sulfate proteoglycan mediates HIV-1 infection of T-cell lines

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12 December 2020

The maturation of dendritic cells results in postintegration inhibition of HIV-1 replication

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12 December 2020

HIV type 1-infected dendritic cells induce apoptotic death in infected and uninfected primary CD4 T lymphocytes

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12 December 2020

HIV-1 Nef equips dendritic cells to reduce survival and function of CD8+ T cells: a mechanism of immune evasion.

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12 December 2020

During HIV-1 infection most blood dendritic cells are not productively infected and can induce allogeneic CD4+ T cells clonal expansion

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12 December 2020

Loss of inducible virus in CD45RA naive cells after human immunodeficiency virus-1 entry accounts for preferential viral replication in CD45RO memory cells.

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12 December 2020

Native HIV-1 Tat protein targets monocyte-derived dendritic cells and enhances their maturation, function, and antigen-specific T cell responses

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12 December 2020

HIV infection of primary human T cells is determined by tunable thresholds of T cell activation

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12 December 2020

Dendritic cells and the control of immunity

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12 December 2020

Decreased stimulation of CD4+ T cell proliferation and IL-2 production by highly enriched populations of HIV-infected dendritic cells

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12 December 2020

HIV-1 Nef-Induced Upregulation of DC-SIGN in Dendritic Cells Promotes Lymphocyte Clustering and Viral Spread

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12 December 2020

Human CD81 directly enhances Th1 and Th2 cell activation, but preferentially induces proliferation of Th2 cells upon long-term stimulation

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12 December 2020

Rhesus macaque dendritic cells efficiently transmit primate lentiviruses independently of DC-SIGN

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12 December 2020

Cellular targets of infection and route of viral dissemination after an intravaginal inoculation of simian immunodeficiency virus into rhesus macaques

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12 December 2020

The HIV-1 vpr protein acts as a negative regulator of apoptosis in a human lymphoblastoid T cell line: possible implications for the pathogenesis of AIDS

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12 December 2020

Mature dendritic cells infected with canarypox virus elicit strong anti-human immunodeficiency virus CD8+ and CD4+ T-cell responses from chronically infected individuals

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12 December 2020

Monocyte-derived cultured dendritic cells are susceptible to human immunodeficiency virus infection and transmit virus to resting T cells in the process of nominal antigen presentation.

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12 December 2020

Depletion of circulating natural type 1 interferon-producing cells in HIV-infected AIDS patients

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12 December 2020

T cell-tropic simian immunodeficiency virus (SIV) and simian-human immunodeficiency viruses are readily transmitted by vaginal inoculation of rhesus macaques, and Langerhans' cells of the female genital tract are infected with SIV.

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12 December 2020

Simian immunodeficiency virus rapidly penetrates the cervicovaginal mucosa after intravaginal inoculation and infects intraepithelial dendritic cells

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12 December 2020

HIV-1 gp120 modulates the immunological function and expression of accessory and co-stimulatory molecules of monocyte-derived dendritic cells

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12 December 2020

Expression of DC-SIGN by dendritic cells of intestinal and genital mucosae in humans and rhesus macaques

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12 December 2020

HIV-1 exposed dendritic cells show increased pro-inflammatory cytokine production but reduced IL-1ra following lipopolysaccharide stimulation

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12 December 2020

Dendritic cells route human immunodeficiency virus to lymph nodes after vaginal or intravenous administration to mice

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12 December 2020

Disrupted homeostasis of Langerhans cells and interdigitating dendritic cells in monkeys with AIDS.

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12 December 2020

A new approach to investigating the relationship between productive infection and cytopathicity in vivo

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12 December 2020

HIV-1 Nef triggers Vav-mediated signaling pathway leading to functional and morphological differentiation of dendritic cells

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12 December 2020

Induction of protective immune responses against R5 human immunodeficiency virus type 1 (HIV-1) infection in hu-PBL-SCID mice by intrasplenic immunization with HIV-1-pulsed dendritic cells: possible involvement of a novel factor of human CD4(+) T-ce

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12 December 2020

Dendritic cell infection, depletion and dysfunction in HIV-infected individuals.

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12 December 2020

DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells

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12 December 2020

HIV-infected Langerhans cells preferentially transmit virus to proliferating autologous CD4+ memory T cells located within Langerhans cell-T cell clusters

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12 December 2020

The role of skin dendritic cells in the initiation of human immunodeficiency virus infection

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12 December 2020

Delivery of liposome-encapsulated HIV type 1 proteins to human dendritic cells for stimulation of HIV type 1-specific memory cytotoxic T lymphocyte responses

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12 December 2020

Distribution and infection of Langerhans cells in the skin of HIV-infected healthy subjects and AIDS patients

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12 December 2020

Primary intestinal epithelial cells selectively transfer R5 HIV-1 to CCR5+ cells

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12 December 2020

Functional antigen-independent synapses formed between T cells and dendritic cells

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12 December 2020

Influence of plasma viremia on defects in number and immunophenotype of blood dendritic cell subsets in human immunodeficiency virus 1-infected individuals

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12 December 2020

DC-SIGN-mediated infectious synapse formation enhances X4 HIV-1 transmission from dendritic cells to T cells

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12 December 2020

Therapeutic dendritic-cell vaccine for simian AIDS.

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12 December 2020

Accumulation of DC-SIGN+CD40+ dendritic cells with reduced CD80 and CD86 expression in lymphoid tissue during acute HIV-1 infection

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12 December 2020

Control of cross-presentation during dendritic cell maturation

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12 December 2020

10.1007/S00281-004-0178-Y

Identifiers

DOI

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11 August 2017

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PubMed ID

15609004