Age-related defects in B lymphopoiesis underlie the myeloid dominance of adult leukemia (Q35990624)

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31 December 2019

title

Age-related defects in B lymphopoiesis underlie the myeloid dominance of adult leukemia (English)

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31 December 2019

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1

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Encarnacion Montecino Rodriguez

31 December 2019

2

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31 December 2019

author name string

Owen N Witte

3

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31 December 2019

Jami McLaughlin

4

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31 December 2019

Kenneth Dorshkind

5

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31 December 2019

language of work or name

English

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publication date

6 June 2007

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31 December 2019

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31 December 2019

volume

110

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31 December 2019

issue

6

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31 December 2019

page(s)

1831-1839

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Aging, B lymphopoiesis, and patterns of leukemogenesis.

31 December 2019

cites work

1 reference

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Targeting multiple kinase pathways in leukemic progenitors and stem cells is essential for improved treatment of Ph+ leukemia in mice.

2 October 2017

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The age incidence of chronic myeloid leukemia can be explained by a one-mutation model

2 October 2017

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Requirement for CD44 in homing and engraftment of BCR-ABL-expressing leukemic stem cells

2 October 2017

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Evolving patterns of lymphopoiesis from embryogenesis through senescence

2 October 2017

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Mechanism and control of V(D)J recombination at the immunoglobulin heavy chain locus

2 October 2017

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Purified hematopoietic stem cell engraftment of rare niches corrects severe lymphoid deficiencies without host conditioning

2 October 2017

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Cell intrinsic alterations underlie hematopoietic stem cell aging.

2 October 2017

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Deficient B lymphopoiesis in murine senescence: potential roles for dysregulation of E2A, Pax-5, and STAT5.

2 October 2017

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Immunosenescence and macrophage functional plasticity: dysregulation of macrophage function by age-associated microenvironmental changes

2 October 2017

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The aging of early B-cell precursors

2 October 2017

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Effects of aging on early B- and T-cell development.

2 October 2017

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Immunosenescence: a problem of lymphopoiesis, homeostasis, microenvironment, and signaling

2 October 2017

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Effects of aging on the homing and engraftment of murine hematopoietic stem and progenitor cells

2 October 2017

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Hematopoietic stem and progenitor cells: clinical and preclinical regeneration of the hematolymphoid system

2 October 2017

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Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML

2 October 2017

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Aging and innate immune cells

2 October 2017

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The BCR-ABL story: bench to bedside and back

2 October 2017

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2 October 2017

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A direct measurement of the radiation sensitivity of normal mouse bone marrow cells

2 October 2017

1 reference

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Origins of chromosome translocations in childhood leukaemia

2 October 2017

1 reference

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A developing picture of lymphopoiesis in bone marrow

2 October 2017

1 reference

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The aging of lympho-hematopoietic stem cells

2 October 2017

1 reference

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Modeling Philadelphia chromosome positive leukemias

2 October 2017

1 reference

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Consequences of BCR-ABL expression within the hematopoietic stem cell in chronic myeloid leukemia

2 October 2017

1 reference

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BCR/ABL inhibition by an escort/phosphatase fusion protein

2 October 2017

1 reference

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A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

2 October 2017

1 reference

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Development and aging of primitive hematopoietic stem cells in BALB/cBy mice

2 October 2017

1 reference

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The P190, P210, and P230 forms of the BCR/ABL oncogene induce a similar chronic myeloid leukemia-like syndrome in mice but have different lymphoid leukemogenic activity

2 October 2017

1 reference

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Commitment to the B lymphoid lineage occurs before DH-JH recombination

2 October 2017

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Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

2 October 2017

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Reduction in superoxide anion secretion and bactericidal activity of neutrophils from aged rats: reversal by the combination of gamma interferon and growth hormone

2 October 2017

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A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

2 October 2017

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Long-term culture of B lymphocytes and their precursors from murine bone marrow

2 October 2017

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Clonal origin of chronic myelocytic leukemia in man

2 October 2017

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Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining

2 October 2017

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BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias

2 October 2017

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Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow

2 October 2017

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RAG-1-deficient mice have no mature B and T lymphocytes

2 October 2017

1 reference

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Chronic myelocytic leukemia: Clonal origin in a stem cell common to the granulocyte, erythrocyte, platelet and monocyte/macrophage

2 October 2017

1 reference

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Age-associated characteristics of murine hematopoietic stem cells

2 October 2017

1 reference

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Identification of clonogenic common lymphoid progenitors in mouse bone marrow

11 July 2018

1 reference

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The aging of hematopoietic stem cells

11 July 2018

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Evidence of a new chimeric bcr/c-abl mRNA in patients with chronic myelocytic leukemia and the Philadelphia chromosome

11 July 2018

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A stromal cell line from myeloid long-term bone marrow cultures can support myelopoiesis and B lymphopoiesis.

11 July 2018

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The chronic myelogenous leukemia-specific P210 protein is the product of the bcr/abl hybrid gene

11 July 2018

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Purification and characterization of mouse hematopoietic stem cells

11 July 2018

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Identification of a B-1 B cell-specified progenitor.

11 July 2018

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Effects of aging on the common lymphoid progenitor to pro-B cell transition

23 September 2018

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Hematopoietic stem cells, leukemic stem cells and chronic myelogenous leukemia.

23 September 2018

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MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors.

23 September 2018

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The decline in B lymphopoiesis in aged mice reflects loss of very early B-lineage precursors.

23 September 2018

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Transcription from the RAG1 locus marks the earliest lymphocyte progenitors in bone marrow

23 September 2018

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Interleukin 3 and granulocyte-macrophage colony-stimulating factor are not required for induction of chronic myeloid leukemia-like myeloproliferative disease in mice by BCR/ABL.

23 September 2018

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Versatile retroviral vectors for potential use in gene therapy

23 September 2018

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Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a

23 September 2018

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Fused transcript of abl and bcr genes in chronic myelogenous leukaemia

14 November 2018

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12 December 2020

Analysis of molecular breakpoint and m-RNA transcripts in a prospective randomized trial of interferon in chronic myeloid leukaemia: no correlation with clinical features, cytogenetic response, duration of chronic phase, or survival

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12 December 2020

Lineage involvement of stem cells bearing the philadelphia chromosome in chronic myeloid leukemia in the chronic phase as shown by a combination of fluorescence-activated cell sorting and fluorescence in situ hybridization

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12 December 2020

Stage-specific alterations in murine B lymphopoiesis with age

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12 December 2020

Distinct patterns of hematopoietic stem cell involvement in acute lymphoblastic leukemia

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12 December 2020

The fate of serially transplanted bone marrow cell populations from young and old donors

1 reference

12 December 2020

Polymorphism of age-related changes in stimulatory capacity of murine dendritic cells

1 reference

12 December 2020

10.1182/BLOOD-2007-01-069401

Identifiers

DOI

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31 December 2019

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31 December 2019

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