Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells (Q36001244)

11 August 2017

Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells (English)

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11 August 2017

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Zsuzsanna K Zsengeller

object named as

Zsuzsanna Zsengellér

5

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author name string

Xueliang Du

1

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11 August 2017

Takeshi Matsumura

2

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11 August 2017

Diane Edelstein

3

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11 August 2017

Luciano Rossetti

4

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11 August 2017

Csaba Szabó

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11 August 2017

Michael Brownlee

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11 August 2017

language of work or name

English

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publication date

1 October 2003

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Journal of Clinical Investigation

11 August 2017

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11 August 2017

112

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11 August 2017

1049-1057

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11 August 2017

7

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describes a project that uses

11 August 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC198524/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy

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A nuclear protein complex containing high mobility group proteins B1 and B2, heat shock cognate protein 70, ERp60, and glyceraldehyde-3-phosphate dehydrogenase is involved in the cytotoxic response to DNA modified by incorporation of anticancer nucl

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Alteration of intracellular structure and function of glyceraldehyde-3-phosphate dehydrogenase: a common phenotype of neurodegenerative disorders?

2 October 2017

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The therapeutic potential of poly(ADP-ribose) polymerase inhibitors

2 October 2017

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Poly(ADP-ribose) polymerase-1 dependence of stress-induced transcription factors and associated gene expression in glia

2 October 2017

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Biochemistry and molecular cell biology of diabetic complications

2 October 2017

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Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site

2 October 2017

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The enzymatic and DNA binding activity of PARP-1 are not required for NF-kappa B coactivator function

2 October 2017

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Reversible nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase upon serum depletion

2 October 2017

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Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation

2 October 2017

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Myocardial postischemic injury is reduced by polyADPripose polymerase-1 gene disruption

2 October 2017

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Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

2 October 2017

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Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group

2 October 2017

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Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts

2 October 2017

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Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosis

2 October 2017

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Glyceraldehyde-3-phosphate dehydrogenase: nuclear translocation participates in neuronal and nonneuronal cell death

2 October 2017

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Targeted overexpression of protein kinase C beta2 isoform in myocardium causes cardiomyopathy

2 October 2017

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Role of the glycolytic protein, glyceraldehyde-3-phosphate dehydrogenase, in normal cell function and in cell pathology

2 October 2017

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CD18/ICAM-1-dependent oxidative NF-kappaB activation leading to nitric oxide production in rat Kupffer cells cocultured with syngeneic hepatoma cells

2 October 2017

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Nitric oxide-induced covalent modification of glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase

2 October 2017

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The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group

2 October 2017

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Stimulation by nitric oxide of an NAD linkage to glyceraldehyde-3-phosphate dehydrogenase

2 October 2017

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Skeletal muscle glycogenolysis is more sensitive to insulin than is glucose transport/phosphorylation. Relation to the insulin-mediated inhibition of hepatic glucose production

2 October 2017

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Demonstration that polyol accumulation is responsible for diabetic cataract by the use of transgenic mice expressing the aldose reductase gene in the lens

2 October 2017

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Protein thiol modification of glyceraldehyde-3-phosphate dehydrogenase as a target for nitric oxide signaling

2 October 2017

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Oxidant injury of cells. DNA strand-breaks activate polyadenosine diphosphate-ribose polymerase and lead to depletion of nicotinamide adenine dinucleotide

2 October 2017

1 reference

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Retardation by Aminoguanidine of Development of Albuminuria, Mesangial Expansion, and Tissue Fluorescence in Streptozocin-Induced Diabetic Rat

2 October 2017

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Aminoguanidine treatment inhibits the development of experimental diabetic retinopathy

2 October 2017

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Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation

2 October 2017

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Effects of diabetes and level of glycemia on all-cause and cardiovascular mortality. The San Antonio Heart Study

11 July 2018

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Nitric oxide-induced S-nitrosylation of glyceraldehyde-3-phosphate dehydrogenase inhibits enzymatic activity and increases endogenous ADP-ribosylation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=198524

Poly(ADP-ribose) polymerase inhibition improves postischemic myocardial function after cardioplegia-cardiopulmonary bypass

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=198524

Effect of poly(ADP ribose) synthetase inhibition on burn and smoke inhalation injury in sheep

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=198524

RAGE blockade stabilizes established atherosclerosis in diabetic apolipoprotein E-null mice.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=198524

Novel phenanthridinone inhibitors of poly (adenosine 5'-diphosphate-ribose) synthetase: potent cytoprotective and antishock agents

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=198524

Inhibition of protein kinase Cbeta prevents impaired endothelium-dependent vasodilation caused by hyperglycemia in humans

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=198524

Anti-inflammatory effects of a novel, potent inhibitor of poly (ADP-ribose) polymerase

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=198524

Rapid reversal of the diabetic endothelial dysfunction by pharmacological inhibition of poly(ADP-ribose) polymerase

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=198524

Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=198524

Nitric oxide regulation of glyceraldehyde-3-phosphate dehydrogenase activity in Dictyostelium discoideum cells and lysates

23 September 2018

1 reference

12 December 2020

Amelioration of vascular dysfunctions in diabetic rats by an oral PKC beta inhibitor

1 reference

12 December 2020

Progression of nephropathy in spontaneous diabetic rats is prevented by OPB-9195, a novel inhibitor of advanced glycation

1 reference

12 December 2020

Activation of nuclear factor-kappaB in cultured endothelial cells by increased glucose concentration: prevention by calphostin C

1 reference

12 December 2020

Overexpression of manganese superoxide dismutase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-kappaB and activated protein-1

1 reference

12 December 2020

Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC beta inhibitor in diabetic db/db mice, a rodent model for type 2 diabetes

1 reference

12 December 2020

The role of poly(ADP-ribose) polymerase activation in the development of myocardial and endothelial dysfunction in diabetes

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI200318127

1 reference

11 August 2017

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11 August 2017

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