Insufficient DNA methylation affects healthy aging and promotes age-related health problems (Q36001915)

11 August 2017

Insufficient DNA methylation affects healthy aging and promotes age-related health problems (English)

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11 August 2017

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Liang Liu

1

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11 August 2017

Thomas van Groen

2

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11 August 2017

Inga Kadish

3

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11 August 2017

Yuanyuan Li

4

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11 August 2017

Deli Wang

5

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11 August 2017

Smitha R James

6

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11 August 2017

Adam R Karpf

7

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11 August 2017

Trygve O Tollefsbol

8

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11 August 2017

language of work or name

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12 June 2011

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11 August 2017

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11 August 2017

2

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11 August 2017

349-360

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11 August 2017

2

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https://scigraph.springernature.com/pub.10.1007/s13148-011-0042-6

11 August 2017

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cites work

Altered histone acetylation is associated with age-dependent memory impairment in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

2 October 2017

Epigenetics and aging.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

Epigenetic mechanisms in the dentate gyrus act as a molecular switch in hippocampus-associated memory formation.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

Epigenetic mechanisms that underpin metabolic and cardiovascular diseases

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

Decline in genomic DNA methylation through aging in a cohort of elderly subjects

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

Epigenetic changes in Alzheimer's disease: decrements in DNA methylation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

Age-specific epigenetic drift in late-onset Alzheimer's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

DNA methylation, insulin resistance, and blood pressure in offspring determined by maternal periconceptional B vitamin and methionine status

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

DNA methylation impacts on learning and memory in aging

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

Epigenetics and aging: the targets and the marks

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

Epigenetic regulation of neural gene expression and neuronal function

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

DNA methylation and human disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

Specific method for the determination of genomic DNA methylation by liquid chromatography-electrospray ionization tandem mass spectrometry

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

Telomerase inhibition by retinoids precedes cytodifferentiation of leukemia cells and may contribute to terminal differentiation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

Transcriptional control of the DNA methyltransferases is altered in aging and neoplastically-transformed human fibroblasts

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

Reversal of age-related learning deficits and brain oxidative stress in mice with superoxide dismutase/catalase mimetics

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

Induction of Tumors in Mice by Genomic Hypomethylation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

Dynamic reprogramming of DNA methylation in the early mouse embryo.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

Does functional depletion of stem cells drive aging?

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

Precision and accuracy of dual-energy X-ray absorptiometry for determining in vivo body composition of mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

Maintenance-type DNA methyltransferase is highly expressed in post-mitotic neurons and localized in the cytoplasmic compartment

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

Changes in memory processing with age.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

The use of animal models to study the effects of aging on cognition

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

Memory deficits associated with senescence: A neurophysiological and behavioral study in the rat

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

Expression of DNA methyltransferase gene in mature and immature neurons as well as proliferating cells in mice.

2 October 2017

1 reference

https://api.crossref.org/works/10.1007%2FS13148-011-0042-6

Is there an epigenetic component in long-term memory?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13148-011-0042-6

Cancer progression in the transgenic adenocarcinoma of mouse prostate mouse is related to energy balance, body mass, and body composition, but not food intake.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13148-011-0042-6

Effects of fimbria-fornix lesion and amyloid pathology on spatial learning and memory in transgenic APP+PS1 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13148-011-0042-6

Decreased methylation of the major mouse long interspersed repeated DNA during aging and in myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13148-011-0042-6

Aging in heterozygous Dnmt1-deficient mice: effects on survival, the DNA methylation genes, and the development of amyloidosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13148-011-0042-6

Effect of age on the radial arm water maze-a test of spatial learning and memory.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13148-011-0042-6

Impact of inflammation on epigenetic DNA methylation - a novel risk factor for cardiovascular disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13148-011-0042-6

Old rats remember old tricks; memories of the water maze persist for 12 months.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13148-011-0042-6

Unexpected effects of a heterozygous dnmt1 null mutation on age-dependent DNA hypomethylation and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13148-011-0042-6

Promoter methylation analysis of SIRT3, SMARCA5, HTERT and CDH1 genes in aging and Alzheimer's disease.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

DNA hypomethylation perturbs the function and survival of CNS neurons in postnatal animals.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

DNA mismatch repair and DNA methylation in adult brain neurons.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365396

Methylation of repetitive DNA sequences in the brain during aging of the rat

23 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22704347

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

An integrated epigenetic and genetic approach to common human disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22704347

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

DNA methylation decreases in aging but not in immortal cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22704347

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S13148-011-0042-6

1 reference

Dimensions Publication ID

11 August 2017

0 references

1 reference

11 August 2017

1 reference