Role of WNK kinases in regulating tubular salt and potassium transport and in the development of hypertension (Q36002090)

11 August 2017

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title

Role of WNK kinases in regulating tubular salt and potassium transport and in the development of hypertension (English)

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11 August 2017

arterial hypertension

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author name string

Gerardo Gamba

series ordinal

1

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11 August 2017

1 February 2005

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American Journal of Physiology - Renal Physiology

11 August 2017

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11 August 2017

288

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11 August 2017

2

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11 August 2017

F245-52

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Biological effects of the dual phenotypic Janus mutation of ret cosegregating with both multiple endocrine neoplasia type 2 and Hirschsprung's disease

11 August 2017

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

WNK1, a kinase mutated in inherited hypertension with hyperkalemia, localizes to diverse Cl- -transporting epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

Gitelman's syndrome revisited: an evaluation of symptoms and health-related quality of life.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

Multiple promoters in the WNK1 gene: one controls expression of a kidney-specific kinase-defective isoform

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

A new locus on chromosome 12p13.3 for pseudohypoaldosteronism type II, an autosomal dominant form of hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

PASK (Proline-Alanine-rich STE20-related Kinase), a Regulatory Kinase of the Na-K-Cl Cotransporter (NKCC1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

Syndrome of hypertension and hyperkalemia with normal glomerular filtration rate

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

Cloning, genomic organization, alternative splicing and expression analysis of the human gene WNK3 (PRKWNK3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

Paracellular Cl- permeability is regulated by WNK4 kinase: insight into normal physiology and hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

Hypertension in mice lacking 11beta-hydroxysteroid dehydrogenase type 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

WNK1 phosphorylates synaptotagmin 2 and modulates its membrane binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

Hypercalciuria in familial hyperkalemia and hypertension accompanies hyperkalemia and precedes hypertension: description of a large family with the Q565E WNK4 mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

Pseudohypoaldosteronism type II: marked sensitivity to thiazides, hypercalciuria, normomagnesemia, and low bone mineral density

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

Crystal structure of the kinase domain of WNK1, a kinase that causes a hereditary form of hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

Human hypertension caused by mutations in the kidney isozyme of 11 beta-hydroxysteroid dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

WNK1, a Gene within a Novel Blood Pressure Control Pathway, Tissue-Specifically Generates Radically Different Isoforms with and without a Kinase Domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

Characterization of the interaction of the stress kinase SPAK with the Na+-K+-2Cl- cotransporter in the nervous system: evidence for a scaffolding role of the kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

Mutations in the human Ca(2+)-sensing receptor gene cause familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

Monogenic hypercholesterolemia: new insights in pathogenesis and treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

Negative regulators of sodium transport in the kidney: key factors in understanding salt-sensitive hypertension?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

Mineralocorticoid-resistant renal hyperkalemia without salt wasting (type II pseudohypoaldosteronism): role of increased renal chloride reabsorption.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

WNK kinases, a novel protein kinase subfamily in multi-cellular organisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

The renal thiazide-sensitive Na-Cl cotransporter as mediator of the aldosterone-escape phenomenon

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

Comparison of WNK4 and WNK1 kinase and inhibiting activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

Human hypertension caused by mutations in WNK kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

WNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain II

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

Regulation of WNK1 by an autoinhibitory domain and autophosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

WNK1 activates ERK5 by an MEKK2/3-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

Disease-causing mutant WNK4 increases paracellular chloride permeability and phosphorylates claudins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

WNK kinases regulate thiazide-sensitive Na-Cl cotransport

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00311.2004

10.1152/AJPRENAL.00311.2004

21 January 2018

Identifiers

DOI

1 reference

11 August 2017

1 reference

PubMed ID

15637347