Aldo-keto reductase family 1 member C3 (AKR1C3) is expressed in adenocarcinoma and squamous cell carcinoma but not small cell carcinoma. (Q36003283)

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3 February 2020

title

Aldo-keto reductase family 1 member C3 (AKR1C3) is expressed in adenocarcinoma and squamous cell carcinoma but not small cell carcinoma (English)

1 reference

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3 February 2020

main subject

squamous cell carcinoma

1 reference

1 reference

5

1 reference

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3 February 2020

author name string

Valerie L Miller

1

1 reference

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3 February 2020

Hsueh-Kung Lin

2

1 reference

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3 February 2020

Paari Murugan

3

1 reference

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3 February 2020

Michael Fan

4

1 reference

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3 February 2020

Lacy S Brame

6

1 reference

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3 February 2020

Qing Yang

7

1 reference

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3 February 2020

Kar-Ming Fung

8

1 reference

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3 February 2020

publication date

26 April 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22670171%20AND%20SRC:MED&resulttype=core&format=json

International Journal of Clinical and Experimental Pathology

3 February 2020

published in

1 reference

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3 February 2020

volume

5

1 reference

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3 February 2020

issue

4

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3 February 2020

page(s)

278-289

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Update on small cell carcinoma and its differentiation from squamous cell carcinoma and other non-small cell carcinomas

3 February 2020

cites work

1 reference

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Differential expression of type 2 3α/type 5 17β-hydroxysteroid dehydrogenase (AKR1C3) in tumors of the central nervous system.

2 October 2017

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Suppressed expression of type 2 3alpha/type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) in endometrial hyperplasia and carcinoma.

2 October 2017

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2 October 2017

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Expression of AKR1C3 in renal cell carcinoma, papillary urothelial carcinoma, and Wilms' tumor

2 October 2017

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Aldo-keto reductase 1C3 expression in MCF-7 cells reveals roles in steroid hormone and prostaglandin metabolism that may explain its over-expression in breast cancer

2 October 2017

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Developmental evaluation of aldo-keto reductase 1C3 expression in the cryptorchid testis

2 October 2017

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Tissue distribution of human AKR1C3 and rat homolog in the adult genitourinary system

2 October 2017

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Dihydrodiol dehydrogenases regulate the generation of reactive oxygen species and the development of cisplatin resistance in human ovarian carcinoma cells

2 October 2017

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A possible role for dihydrodiol dehydrogenase in the formation of benzo[a]pyrene-DNA adducts in lung cancer cells and tumor tissues

2 October 2017

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Expression of dihydrodiol dehydrogenase and resistance to chemotherapy and radiotherapy in adenocarcinoma cells of lung.

2 October 2017

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Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer

2 October 2017

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17Beta-hydroxysteroid dehydrogenases in human endometrium and its disorders

2 October 2017

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Expression of dihydrodiol dehydrogenase plays important roles in apoptosis- and drug-resistance of A431 squamous cell carcinoma.

2 October 2017

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Metabolic activation of polycyclic and heterocyclic aromatic hydrocarbons and DNA damage: a review

2 October 2017

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Oxidative DNA damage induced by benz[a]anthracene dihydrodiols in the presence of dihydrodiol dehydrogenase

2 October 2017

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Expression of progesterone metabolizing enzyme genes (AKR1C1, AKR1C2, AKR1C3, SRD5A1, SRD5A2) is altered in human breast carcinoma

2 October 2017

1 reference

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Regulation of postnatal lung development and homeostasis by estrogen receptor beta.

2 October 2017

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Human type 3 3alpha-hydroxysteroid dehydrogenase (aldo-keto reductase 1C2) and androgen metabolism in prostate cells.

2 October 2017

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Activation of polycyclic aromatic hydrocarbon trans-dihydrodiol proximate carcinogens by human aldo-keto reductase (AKR1C) enzymes and their functional overexpression in human lung carcinoma (A549) cells

2 October 2017

1 reference

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Expression of dihydrodiol dehydrogenase in the resected stage I non-small cell lung cancer

2 October 2017

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Increased expression of dihydrodiol dehydrogenase induces resistance to cisplatin in human ovarian carcinoma cells.

2 October 2017

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Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones

2 October 2017

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2 October 2017

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Identification of a principal mRNA species for human 3alpha-hydroxysteroid dehydrogenase isoform (AKR1C3) that exhibits high prostaglandin D2 11-ketoreductase activity

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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23 September 2018

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AKR1C1 and AKR1C3 may determine progesterone and estrogen ratios in endometrial cancer

23 September 2018

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23 September 2018

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Characterization of a monoclonal antibody for human aldo-keto reductase AKR1C3 (type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase); immunohistochemical detection in breast and prostate

23 September 2018

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Oxidative damage-related genes AKR1C3 and OGG1 modulate risks for lung cancer due to exposure to PAH-rich coal combustion emissions.

23 September 2018

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Ubiquitous induction of resistance to platinum drugs in human ovarian, cervical, germ-cell and lung carcinoma tumor cells overexpressing isoforms 1 and 2 of dihydrodiol dehydrogenase

23 September 2018

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23 September 2018

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Overexpression of dihydrodiol dehydrogenase as a prognostic marker of non-small cell lung cancer

23 September 2018

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Dihydrodiol dehydrogenases and polycyclic aromatic hydrocarbon activation: generation of reactive and redox active o-quinones.

23 September 2018

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23 September 2018

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In situ androgen producing enzymes in human prostate cancer

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1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22670171

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Increased expression of type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) and its relationship with androgen receptor in prostate carcinoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22670171

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Napsin A, a new marker for lung adenocarcinoma, is complementary and more sensitive and specific than thyroid transcription factor 1 in the differential diagnosis of primary pulmonary carcinoma: evaluation of 1674 cases by tissue microarray

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22670171

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22670171%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

PubMed publication ID

22670171

1 reference