Safety and efficacy of everolimus, a mTOR inhibitor, as single agent in a phase 1/2 study in patients with myelofibrosis. (Q36003480)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21725052%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

title

Safety and efficacy of everolimus, a mTOR inhibitor, as single agent in a phase 1/2 study in patients with myelofibrosis (English)

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6 February 2020

1

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6 February 2020

Lorenzo Tozzi

6

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6 February 2020

Niccolò Bartalucci

8

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6 February 2020

Alessandro Pancrazzi

12

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6 February 2020

Lisa Pieri

15

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6 February 2020

Alberto Bosi

22

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6 February 2020

23

Tiziano Barbui

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6 February 2020

author name string

Giovanni Barosi

2

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6 February 2020

Alessandro Rambaldi

3

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6 February 2020

Roberto Marchioli

4

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6 February 2020

Arianna Masciulli

5

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6 February 2020

Flavia Biamonte

7

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6 February 2020

Elisabetta Gattoni

9

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Maria Letizia Lupo

10

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Guido Finazzi

11

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6 February 2020

Elisabetta Antonioli

13

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Maria Chiara Susini

14

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6 February 2020

Elisa Malevolti

16

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Emilio Usala

17

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6 February 2020

Ubaldo Occhini

18

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Alberto Grossi

19

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Silvia Caglio

20

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Simona Paratore

21

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Alessandro M Vannucchi

24

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AIRC-Gruppo Italiano Malattie Mieloproliferative (AGIMM) investigators

25

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language of work or name

English

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publication date

1 July 2011

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6 February 2020

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6 February 2020

volume

118

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6 February 2020

page(s)

2069-2076

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6 February 2020

issue

8

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Circulating interleukin (IL)-8, IL-2R, IL-12, and IL-15 levels are independently prognostic in primary myelofibrosis: a comprehensive cytokine profiling study

6 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365876

Safety and efficacy of TG101348, a selective JAK2 inhibitor, in myelofibrosis

2 October 2017

1 reference

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How I treat myelofibrosis

2 October 2017

1 reference

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Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis

2 October 2017

1 reference

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Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders

2 October 2017

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New inhibitors of the mammalian target of rapamycin signaling pathway for cancer.

2 October 2017

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A pilot study of the Histone-Deacetylase inhibitor Givinostat in patients with JAK2V617F positive chronic myeloproliferative neoplasms

2 October 2017

1 reference

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Novel mutations and their functional and clinical relevance in myeloproliferative neoplasms: JAK2, MPL, TET2, ASXL1, CBL, IDH and IKZF1

2 October 2017

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Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms.

2 October 2017

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Conditional expression of heterozygous or homozygous Jak2V617F from its endogenous promoter induces a polycythemia vera-like disease

2 October 2017

1 reference

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Pomalidomide is active in the treatment of anemia associated with myelofibrosis

2 October 2017

1 reference

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Targeting PI3K signalling in cancer: opportunities, challenges and limitations

2 October 2017

1 reference

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Identification of patients with poorer survival in primary myelofibrosis based on the burden of JAK2V617F mutated allele

2 October 2017

1 reference

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Advances in understanding and management of myeloproliferative neoplasms

2 October 2017

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Selective inhibition of JAK2-driven erythroid differentiation of polycythemia vera progenitors

2 October 2017

1 reference

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Role of JAK2 in the pathogenesis and therapy of myeloproliferative disorders

2 October 2017

1 reference

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Defining the role of mTOR in cancer

2 October 2017

1 reference

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Proposals and rationale for revision of the World Health Organization diagnostic criteria for polycythemia vera, essential thrombocythemia, and primary myelofibrosis: recommendations from an ad hoc international expert panel

2 October 2017

1 reference

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International Working Group (IWG) consensus criteria for treatment response in myelofibrosis with myeloid metaplasia, for the IWG for Myelofibrosis Research and Treatment (IWG-MRT).

2 October 2017

1 reference

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Response criteria for myelofibrosis with myeloid metaplasia: results of an initiative of the European Myelofibrosis Network (EUMNET).

2 October 2017

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A sensitive detection method for MPLW515L or MPLW515K mutation in chronic myeloproliferative disorders with locked nucleic acid-modified probes and real-time polymerase chain reaction.

2 October 2017

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The Myeloproliferative Neoplasm Symptom Assessment Form (MPN-SAF): international prospective validation and reliability trial in 402 patients.

11 July 2018

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From palliation to targeted therapy in myelofibrosis.

23 September 2018

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Phospho-STAT5 and phospho-Akt expression in chronic myeloproliferative neoplasms.

23 September 2018

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Molecular profiling of CD34+ cells in idiopathic myelofibrosis identifies a set of disease-associated genes and reveals the clinical significance of Wilms' tumor gene 1 (WT1).

23 September 2018

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Multiple signaling pathways are involved in erythropoietin-independent differentiation of erythroid progenitors in polycythemia vera.

23 September 2018

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23 September 2018

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12 December 2020

Myelofibrosis with myeloid metaplasia

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12 December 2020

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10.1182/BLOOD-2011-01-330563

Identifiers

DOI

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