Methoxychlor inhibits growth and induces atresia through the aryl hydrocarbon receptor pathway in mouse ovarian antral follicles. (Q36007784)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22484361%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

title

Methoxychlor inhibits growth and induces atresia through the aryl hydrocarbon receptor pathway in mouse ovarian antral follicles (English)

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28 January 2020

author name string

Mallikarjuna S Basavarajappa

series ordinal

1

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28 January 2020

Wei Wang

series ordinal

3

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28 January 2020

publication date

30 March 2012

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28 January 2020

published in

Reproductive Toxicology

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28 January 2020

volume

34

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28 January 2020

issue

1

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28 January 2020

page(s)

16-21

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Methoxychlor reduces estradiol levels by altering steroidogenesis and metabolism in mouse antral follicles in vitro.

28 January 2020

cites work

1 reference

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Methoxychlor inhibits growth of antral follicles by altering cell cycle regulators.

2 October 2017

1 reference

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The role of the aryl hydrocarbon receptor in the female reproductive system

2 October 2017

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Developmental methoxychlor exposure affects multiple reproductive parameters and ovarian folliculogenesis and gene expression in adult rats

2 October 2017

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Transient inhibitory effect of methoxychlor on testicular steroidogenesis in rat: an in vivo study

2 October 2017

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Methoxychlor suppresses the 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-inducible CYP1A1 expression in murine Hepa-1c1c7 cells

2 October 2017

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Intrinsic function of the aryl hydrocarbon (dioxin) receptor as a key factor in female reproduction

2 October 2017

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Differential gene expression in response to methoxychlor and estradiol through ERalpha, ERbeta, and AR in reproductive tissues of female mice.

2 October 2017

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Effect of single and compound knockouts of estrogen receptors alpha (ERalpha) and beta (ERbeta) on mouse reproductive phenotypes

2 October 2017

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Methoxychlor stimulates estrogen-responsive messenger ribonucleic acids in mouse uterus through a non-estrogen receptor (non-ER) alpha and non-ER beta mechanism

2 October 2017

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Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the cyp19 gene

2 October 2017

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Environmental endocrine disruption: an effects assessment and analysis

2 October 2017

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The Ah receptor: mediator of the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and related compounds

2 October 2017

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Xenobiotic-inducible transcription of cytochrome P450 genes.

2 October 2017

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Organization and function of a dioxin-responsive enhancer

2 October 2017

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Effects of methoxychlor treatment of pregnant mice on female offspring of the treated and subsequent pregnancies

2 October 2017

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Stereospecific, high affinity binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin by hepatic cytosol. Evidence that the binding species is receptor for induction of aryl hydrocarbon hydroxylase

2 October 2017

1 reference

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2,3,7,8-Tetrachlorodibenzo-p-dioxin increases steady-state estrogen receptor-beta mRNA levels after CYP1A1 and CYP1B1 induction in rat granulosa cells in vitro

2 October 2017

1 reference

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Neonatal exposures to technical methoxychlor alters ovaries in adult mice

11 July 2018

1 reference

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Binding of 3-methylcholanthrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin to a common Ah receptor site in mouse and rat hepatic cytosols

11 July 2018

1 reference

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The effect of intraovarian injection of benzo(a)pyrene on primordial oocyte number and ovarian aryl hydrocarbon [benzo(a)pyrene] hydroxylase activity

11 July 2018

1 reference

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Binding of benzo(a)pyrene and dibenz(a,h)anthracene to the Ah receptor in mouse and rat hepatic cytosols

11 July 2018

1 reference

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Effects of methoxychlor on the reproductive system of the adult female mouse 1. Gross and histologic observations

11 July 2018

1 reference

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Methoxychlor inhibits growth and induces atresia of antral follicles through an oxidative stress pathway.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3367105

Methoxychlor metabolites may cause ovarian toxicity through estrogen-regulated pathways.

23 September 2018

1 reference

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Demethylation of the pesticide methoxychlor in liver and intestine from untreated, methoxychlor-treated, and 3-methylcholanthrene-treated channel catfish (Ictalurus punctatus): evidence for roles of CYP1 and CYP3A family isozymes

23 September 2018

1 reference

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Methoxychlor directly affects ovarian antral follicle growth and atresia through Bcl-2- and Bax-mediated pathways

23 September 2018

1 reference

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Hepatic CYP1A, 2B, 2C, 2E and 3A regulation by methoxychlor in male and female rats

23 September 2018

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Methoxychlor may cause ovarian follicular atresia and proliferation of the ovarian epithelium in the mouse

23 September 2018

1 reference

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Ligand activation of the aromatic hydrocarbon receptor transcription factor drives Bax-dependent apoptosis in developing fetal ovarian germ cells

23 September 2018

1 reference

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Aromatic hydrocarbon receptor-driven Bax gene expression is required for premature ovarian failure caused by biohazardous environmental chemicals

23 September 2018

1 reference

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Interaction of methoxychlor and related compounds with estrogen receptor alpha and beta, and androgen receptor: structure-activity studies.

23 September 2018

1 reference

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Murine oocyte destruction following intraovarian treatment with 3-methylcholanthrene or 7,12-dimethylbenz(a)anthracene: Protection by alpha-naphthoflavone

23 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22484361

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.REPROTOX.2012.03.007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22484361%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

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28 January 2020

PubMed publication ID

22484361

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22484361%20AND%20SRC:MED&resulttype=core&format=json