Metabolism and antiviral activity of ribavirin (Q36008881)

11 August 2017

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title

Metabolism and antiviral activity of ribavirin (English)

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11 August 2017

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William B Parker

1

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11 August 2017

1 February 2005

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11 August 2017

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11 August 2017

107

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11 August 2017

165-171

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11 August 2017

2

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Modulation of nicotinamide adenine dinucleotide and poly(adenosine diphosphoribose) metabolism by the synthetic "C" nucleoside analogs, tiazofurin and selenazofurin. A new strategy for cancer chemotherapy

11 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Initial Binding of the Broad Spectrum Antiviral Nucleoside Ribavirin to the Hepatitis C Virus RNA Polymerase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Incorporation fidelity of the viral RNA-dependent RNA polymerase: a kinetic, thermodynamic and structural perspective

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Viral RNA mutations are region specific and increased by ribavirin in a full-length hepatitis C virus replication system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

RNA virus error catastrophe: direct molecular test by using ribavirin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Ribavirin's antiviral mechanism of action: lethal mutagenesis?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Viruses at the edge of adaptation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Error catastrophe and antiviral strategy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Inhibition of influenza virus ribonucleic acid polymerase by ribavirin triphosphate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Molecular analysis of the inhibitory effect of phosphorylated ribavirin on the vesicular stomatitis virus in vitro polymerase reaction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Structural analysis of the activation of ribavirin analogs by NDP kinase: comparison with other ribavirin targets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Ribavirin, tiazofurin, and selenazofurin: mononucleotides and nicotinamide adenine dinucleotide analogues. Synthesis, structure, and interactions with IMP dehydrogenase.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Comparison of biochemical parameters of benzamide riboside, a new inhibitor of IMP dehydrogenase, with tiazofurin and selenazofurin.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Biochemistry and clinical applications of ribavirin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Quasispecies, error catastrophe, and the antiviral activity of ribavirin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Mechanism of resistance to the oncolytic C-nucleoside 2-beta-D-ribofuranosylthiazole-4-carboxamide (NSC-286193).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Conversion of 2-β-D-ribofuranosylselenazole-4-carboxamide to an analogue of nad with potent imp dehydrogenase-inhibitory properties

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Pyrimidine Nucleotide Biosynthesis in Animals: Genes, Enzymes, and Regulation of UMP Biosynthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Broad-spectrum antiviral activity of 2-beta-D-ribofuranosylselenazole-4-carboxamide, a new antiviral agent

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Broad-spectrum synergistic antiviral activity of selenazofurin and ribavirin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Ribavirin Induces Error-Prone Replication of GB Virus B in Primary Tamarin Hepatocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Hepatitis C virus RNA-dependent RNA polymerase (NS5B) as a mediator of the antiviral activity of ribavirin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Inhibitors of IMP dehydrogenase prevent sindbis virus replication and reduce GTP levels in Aedes albopictus cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

The relationship between the metabolism of ribavirin and its proposed mechanism of action

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Virazole (1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide; a cytostatic agent.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

The metabolism of ribavirin in erythrocytes and nucleated cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Metabolism and action of purine nucleoside analogs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Studies on the mechanism of the antiviral activity of ribavirin against reovirus.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

The importance of IMP dehydrogenase inhibition in the broad spectrum antiviral activity of ribavirin and selenazofurin.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Ribavirin causes error catastrophe during Hantaan virus replication.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Broad-spectrum antiviral activity of Virazole: 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Ribavirin: An antiviral agent

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Metabolism of ribavirin in respiratory syncytial virus-infected and uninfected cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Antiviral activity and mode of action studies of ribavirin and mycophenolic acid against orthopoxviruses in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Mechanism of action of 1- -D-ribofuranosyl-1,2,4-triazole-3-carboxamide (Virazole), a new broad-spectrum antiviral agent

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

The phosphorylation of ribavirin by deoxyadenosine kinase from rat liver. Differentiation between adenosine and deoxyadenosine kinase.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Mechanisms of action of ribavirin in antiviral therapies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Effect of phosphorylated ribavirin on vesicular stomatitis virus transcription

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

The Quest for an Efficacious Antiviral for Respiratory Syncytial Virus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Mutagenic and inhibitory effects of ribavirin on hepatitis C virus RNA polymerase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Adenosine kinase initiates the major route of ribavirin activation in a cultured human cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Mode of action of ribavirin: effect of nucleotide pool alterations on influenza virus ribonucleoprotein synthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Effect of ribavirin triphosphate on primer generation and elongation during influenza virus transcription in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Adenosine kinase from human liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Action of the active metabolites of tiazofurin and ribavirin on purified IMP dehydrogenase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

IMP dehydrogenase and action of antimetabolites in human cultured blast cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

The effect of ribavirin and IMPDH inhibitors on hepatitis C virus subgenomic replicon RNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Metabolism of 5-amino-1-β-d-ribofuranosyl- imidazole-4-carboxamide and related five-membered heterocycles to 5′-triphosphates in human blood and L5178Y cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

Molecular mechanisms of action of ribavirin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.006

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.VIRUSRES.2004.11.006

1 reference

11 August 2017

1 reference

PubMed ID

15649562