The Tpl-2 protooncoprotein activates the nuclear factor of activated T cells and induces interleukin 2 expression in T cell lines. (Q36010927)

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10 November 2019

title

The Tpl-2 protooncoprotein activates the nuclear factor of activated T cells and induces interleukin 2 expression in T cell lines (English)

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10 November 2019

1

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10 November 2019

author name string

C Patriotis

series ordinal

2

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10 November 2019

S E Bear

series ordinal

3

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10 November 2019

P N Tsichlis

series ordinal

4

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10 November 2019

language of work or name

English

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publication date

1 March 1998

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Proceedings of the National Academy of Sciences of the United States of America

10 November 2019

number of pages

6

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based on heuristic

inferred from page(s)

published in

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10 November 2019

volume

95

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10 November 2019

issue

7

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10 November 2019

page(s)

3827-3832

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Nuclear accumulation of NFAT4 opposed by the JNK signal transduction pathway

10 November 2019

cites work

1 reference

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NF-AT activation induced by a CAML-interacting member of the tumor necrosis factor receptor superfamily

2 October 2017

1 reference

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Cot kinase regulation of IL-2 production in Jurkat T cells

2 October 2017

1 reference

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Transcription factors of the NFAT family: regulation and function

2 October 2017

1 reference

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Differential activation of transcription factors induced by Ca2+ response amplitude and duration

2 October 2017

1 reference

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Expression of NFAT-family proteins in normal human T cells

2 October 2017

1 reference

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Suppression of signalling through transcription factor NF-AT by interactions between calcineurin and Bcl-2.

2 October 2017

1 reference

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Tpl-2 is an oncogenic kinase that is activated by carboxy-terminal truncation

2 October 2017

1 reference

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Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3

2 October 2017

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Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase

2 October 2017

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Involvement of the Tpl-2/cot oncogene in MMTV tumorigenesis

2 October 2017

1 reference

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The Gfi-1 proto-oncoprotein contains a novel transcriptional repressor domain, SNAG, and inhibits G1 arrest induced by interleukin-2 withdrawal

2 October 2017

1 reference

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Cross talk between cell death and cell cycle progression: BCL-2 regulates NFAT-mediated activation.

2 October 2017

1 reference

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Gfi-1 encodes a nuclear zinc finger protein that binds DNA and functions as a transcriptional repressor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922

Activation of MEK-1 and SEK-1 by Tpl-2 proto-oncoprotein, a novel MAP kinase kinase kinase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922

Regulation of AP-1 and NFAT transcription factors during thymic selection of T cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922

2 October 2017

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Genomic organization and expression of Tpl-2 in normal cells and Moloney murine leukemia virus-induced rat T-cell lymphomas: activation by provirus insertion.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922

Characterization of the nuclear and cytoplasmic components of the lymphoid-specific nuclear factor of activated T cells (NF-AT) complex.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922

Beta-galactosidase and chloramphenicol acetyltransferase assays in 96-well plates

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922

NF-AT components define a family of transcription factors targeted in T-cell activation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922

Signal transmission between the plasma membrane and nucleus of T lymphocytes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922

Tpl-2 acts in concert with Ras and Raf-1 to activate mitogen-activated protein kinase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922

Tumor progression locus 2 (Tpl-2) encodes a protein kinase involved in the progression of rodent T-cell lymphomas and in T-cell activation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922

Novel NFAT sites that mediate activation of the interleukin-2 promoter in response to T-cell receptor stimulation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922

Transcriptional regulation of the IL-2 gene

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922

Characterization of antigen receptor response elements within the interleukin-2 enhancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922

Contingent genetic regulatory events in T lymphocyte activation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922

Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922

Regulation of Interleukin-2 Gene Enhancer Activity by the T Cell Accessory Molecule CD28

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922

cis-acting sequences required for inducible interleukin-2 enhancer function bind a novel Ets-related protein, Elf-1.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922

Involvement of phosphatidylinositol 3-kinase in NFAT activation in T cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922

Ras-dependent, Ca2+-stimulated activation of nuclear factor of activated T cells by a constitutively active Cbl mutant in T cells.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922

Cytoplasmic domains of the interleukin-2 receptor beta and gamma chains mediate the signal for T-cell proliferation.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922

A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922

11 July 2018

Identifiers

DOI

10.1073/PNAS.95.7.3827

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10 November 2019

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10 November 2019

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