FFAs: do they play a role in vascular disease in the insulin resistance syndrome? (Q36016946)

11 August 2017

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title

FFAs: do they play a role in vascular disease in the insulin resistance syndrome? (English)

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11 August 2017

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Sudha S Shankar

1

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PubMed ID

15663914

11 August 2017

Helmut O Steinberg

series ordinal

2

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11 August 2017

1 February 2005

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11 August 2017

Current diabetes report

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11 August 2017

5

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11 August 2017

1

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11 August 2017

30-35

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https://scigraph.springernature.com/pub.10.1007/s11892-005-0064-6

11 August 2017

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cites work

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Oleic acid inhibits endothelial nitric oxide synthase by a protein kinase C-independent mechanism

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Inhibiting NOS blocks microvascular recruitment and blunts muscle glucose uptake in response to insulin

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Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells

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Unsaturated fatty acids selectively induce an inflammatory environment in human endothelial cells

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Effects of acute changes of plasma free fatty acids on intramyocellular fat content and insulin resistance in healthy subjects

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Elevation of free fatty acids induces inflammation and impairs vascular reactivity in healthy subjects

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Free fatty acid elevation impairs insulin-mediated vasodilation and nitric oxide production

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12 December 2020

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Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release

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Nitric oxide release accounts for insulin's vascular effects in humans

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Fatty acids differentially modulate insulin-stimulated endothelial nitric oxide production by an Akt-independent pathway

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Insulin resistance in non-diabetic subjects is associated with increased incidence of myocardial infarction and death

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Free fatty acid levels modulate microvascular function: relevance for obesity-associated insulin resistance, hypertension, and microangiopathy

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Vascular function, insulin resistance and fatty acids

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12 December 2020

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Relationship between insulin resistance and an endogenous nitric oxide synthase inhibitor

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Insulin-mediated changes in leg blood flow are coupled to capillary density in skeletal muscle in healthy 70-year-old men.

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12 December 2020

Lipid infusion impairs physiologic insulin-mediated capillary recruitment and muscle glucose uptake in vivo

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12 December 2020

Endothelium-dependent vasodilation is related to the fatty acid composition of serum lipids in healthy subjects

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12 December 2020

Mechanisms of fatty acid-induced inhibition of glucose uptake

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12 December 2020

10.1007/S11892-005-0064-6

Identifiers

DOI

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11 August 2017

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PubMed ID

15663914