Pharmacological and biochemical aspects of GABAergic neurotransmission: pathological and neuropsychobiological relationships (Q36020907)

11 August 2017

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title

Pharmacological and biochemical aspects of GABAergic neurotransmission: pathological and neuropsychobiological relationships (English)

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11 August 2017

Norberto Cysne Coimbra

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object named as

Norberto Cysne Coimbra

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author name string

Renê Oliveira Beleboni

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11 August 2017

Ruither Oliveira Gomes Carolino

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11 August 2017

Andrea Baldocchi Pizzo

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11 August 2017

Lissandra Castellan-Baldan

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11 August 2017

Joaquim Coutinho-Netto

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11 August 2017

Wagner Ferreira dos Santos

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11 August 2017

Norberto Cysne Coimbra

7

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11 August 2017

language of work or name

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1 December 2004

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Cellular and Molecular Neurobiology

11 August 2017

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11 August 2017

24

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11 August 2017

6

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11 August 2017

707-728

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https://scigraph.springernature.com/pub.10.1007/s10571-004-6913-z

11 August 2017

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Ethyl β-carboline-3-carboxylate shows differential benzodiazepine receptor interaction

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Neuronal and glial γ-aminobutyric acid+ transporters are distinct proteins

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GABAA receptor binding in the aging rat inferior colliculus

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Effects of opioid receptor blockade on defensive behavior elicited by electrical stimulation of the aversive substrates of the inferior colliculus in Rattus norvegicus (Rodentia, Muridae).

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Effects of the blockade of opioid receptor on defensive reactions elicited by electrical stimulation within the deep layers of the superior colliculus and DPAG.

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THIP, isoguvacine, isoguvacine oxide, and related GABA agonists.

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Projections from the substantia nigra pars reticulata to the motor thalamus of the rat: single axon reconstructions and immunohistochemical study

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Two distinct mechanisms, differentially affected by excitatory amino acids, trigger GABA release from fetal mouse striatal neurons in primary culture

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GABAA/benzodiazepine receptor heterogeneity: neurophysiological implications.

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12 December 2020

Modulation by GABA transmission in the substantia nigra compacta and reticulata of locomotor activity in rats exposed to high pressure.

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12 December 2020

GABA: an excitatory transmitter in early postnatal life

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GABA plasma membrane transporters, GAT-1 and GAT-3, display different distributions in the rat hippocampus

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A new benzodiazepine pharmacology.

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GABAB-receptor-activated K+ current in voltage-clamped CA3 pyramidal cells in hippocampal cultures

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Synthesis of novel gamma-aminobutyric acid (GABA) uptake inhibitors. 5.(1) Preparation and structure-activity studies of tricyclic analogues of known GABA uptake inhibitors

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Common structural organization of two output nuclei of primate basal ganglia.

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Bidirectional movement of gamma-aminobutyric acid in rat spinal cord slices

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In vivo release of neuroactive amino acids from the inferior colliculus of the guinea pig using brain microdialysis.

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gamma-Vinyl GABA (4-amino-hex-5-enoic acid), a new selective irreversible inhibitor of GABA-T: effects on brain GABA metabolism in mice

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Defensive reactions evoked by activation of NMDA receptors in distinct sites of the inferior colliculus.

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12 December 2020

Proconvulsant, convulsant and other actions of the D- and L-stereoisomers of allylglycine in the photosensitive baboon, Papio papio

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12 December 2020

GABA shapes sensitivity to interaural intensity disparities in the mustache bat's inferior colliculus: implications for encoding sound location.

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12 December 2020

Inhibitors of gamma-aminobutyric acid transport as experimental tools and therapeutic agents.

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12 December 2020

Phorbol esters increase dopamine transporter phosphorylation and decrease transport Vmax

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12 December 2020

The effect of unilateral claustral lesion on intermittent light stimulation induced seizure in D, L-allylglycine treated cats.

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12 December 2020

Central nucleus of the amygdala and the control of tonic immobility in guinea pigs

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12 December 2020

Molecular characterization of four pharmacologically distinct gamma-aminobutyric acid transporters in mouse brain [corrected].

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12 December 2020

The pharmacology of GABA-transaminase inhibitors

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12 December 2020

GABAergic fibers from substantia nigra pars reticulata modulate escape behavior induced by midbrain central gray stimulation

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12 December 2020

Uptake and metabolism of γ-aminobutyric acid by neurones and glial cells

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12 December 2020

GABA transporter heterogeneity: pharmacology and cellular localization

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12 December 2020

The cholinergic stimulation of the central amygdala modifying the tonic immobility response and antinociception in guinea pigs depends on the ventrolateral periaqueductal gray

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12 December 2020

Free gamma-aminobutyric acid in brain.

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12 December 2020

Separate domains for desensitization of GABA rho 1 and beta 2 subunits expressed in Xenopus oocytes

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12 December 2020

Synthesis of novel GABA uptake inhibitors. Part 6: preparation and evaluation of N-Omega asymmetrically substituted nipecotic acid derivatives

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12 December 2020

Neurotransmitter transporters. A novel family of integral plasma membrane proteins

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12 December 2020

An update on GABAA receptors

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12 December 2020

Molecular and neuronal substrate for the selective attenuation of anxiety.

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12 December 2020

Characterization of [3H]GABA release from striatal slices: evidence for a calcium-independent process via the GABA uptake system.

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12 December 2020

Inhibition of gamma-aminobutyric acid synthesis by glutamic acid decarboxylase autoantibodies in stiff-man syndrome

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12 December 2020

GABA(B) receptor agonists for the treatment of drug addiction: a review of recent findings

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12 December 2020

Interactions between dopamine D1 receptors and gamma-aminobutyric acid mechanisms in substantia nigra pars reticulata of the rat: neurochemical and behavioral studies

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12 December 2020

SL651498, a GABAA receptor agonist with subtype-selective efficacy, as a potential treatment for generalized anxiety disorder and muscle spasms.

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12 December 2020

Regulation of gamma-aminobutyric acid synthesis in the brain

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12 December 2020

Inhibition of gamma-aminobutyrate and glycine uptake into synaptic vesicles.

1 reference

12 December 2020

GABA(A) receptor ligands and their therapeutic potentials

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12 December 2020

GABA and pancreatic beta-cells: colocalization of glutamic acid decarboxylase (GAD) and GABA with synaptic-like microvesicles suggests their role in GABA storage and secretion.

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12 December 2020

Advances in the medical treatment of epilepsy

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12 December 2020

The neostriatal mosaic: multiple levels of compartmental organization in the basal ganglia

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12 December 2020

Escape behavior produced by the blockade of glutamic acid decarboxylase (GAD) in mesencephalic central gray or medial hypothalamus

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12 December 2020

Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes.

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12 December 2020

Epilepsy, hyperalgesia, impaired memory, and loss of pre- and postsynaptic GABA(B) responses in mice lacking GABA(B(1)).

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12 December 2020

Active site model for gamma-aminobutyrate aminotransferase explains substrate specificity and inhibitor reactivities

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12 December 2020

Antiepileptic drugs in schizophrenia: a review

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12 December 2020

Numbers and proportions of GABA-immunoreactive neurons in different areas of monkey cerebral cortex

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12 December 2020

H+ permeation and pH regulation at a mammalian serotonin transporter.

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12 December 2020

The GABA-glutamate connection in schizophrenia: which is the proximate cause?

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12 December 2020

Dorsolateral and ventral regions of the periaqueductal gray matter are involved in distinct types of fear.

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12 December 2020

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12 December 2020

The family of Na+/Cl- neurotransmitter transporters.

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12 December 2020

GABAA receptor pharmacology

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12 December 2020

Evidence for a G protein-coupled gamma-hydroxybutyric acid receptor

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12 December 2020

Defensive freezing evoked by electrical stimulation of the periaqueductal gray: comparison between dorsolateral and ventrolateral regions.

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12 December 2020

A tale of two transmitters

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12 December 2020

The relevance of neuronal substrates of defense in the midbrain tectum to anxiety and stress: empirical and conceptual considerations

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12 December 2020

Increase in brain GABA-transaminase activity after chronic ethanol treatment in rats

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12 December 2020

The neurobiology and control of anxious states

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12 December 2020

Carrier-mediated GABA release activates GABA receptors on hippocampal neurons.

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12 December 2020

Neuroanatomical and psychopharmacological evidence for interaction between opioid and GABAergic neural pathways in the modulation of fear and defense elicited by electrical and chemical stimulation of the deep layers of the superior colliculus and d

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12 December 2020

Role of the substantia nigra pars reticulata in sensorimotor gating, measured by prepulse inhibition of startle in rats.

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12 December 2020

Spontaneous REM sleep is modulated by the activation of the pedunculopontine tegmental GABAB receptors in the freely moving rat.

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12 December 2020

Cis- and trans-4-aminocrotonic acid as GABA analogues of restricted conformation

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12 December 2020

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12 December 2020

Antiaversive action of benzodiazepines on escape behavior induced by electrical stimulation of the inferior colliculus

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12 December 2020

Cloning and expression of a betaine/GABA transporter from human brain

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12 December 2020

GABA uptake inhibitors: relevance to antiepileptic drug research

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12 December 2020

GABA uptake inhibitors. Design, molecular pharmacology and therapeutic aspects

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12 December 2020

GABA Transaminase Inhibitors

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12 December 2020

GABA and affective disorders.

1 reference

12 December 2020

Expression of mammalian gamma-aminobutyric acid receptors with distinct pharmacology in Xenopus oocytes

1 reference

12 December 2020

GABA(A) receptor function and pharmacology in epilepsy and status epilepticus.

1 reference

12 December 2020

The role of the synthetic enzyme GAD65 in the control of neuronal gamma-aminobutyric acid release

1 reference

12 December 2020

3H-baclofen and 3H-GABA bind to bicuculline-insensitive GABAB sites in rat brain

1 reference

12 December 2020

Effects of unilateral microinjections of GABAergic drugs into the inferior colliculus on auditory evoked potentials and on audiogenic seizure susceptibility

1 reference

12 December 2020

Channels in transporters.

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12 December 2020

International Union of Pharmacology. XXXIII. Mammalian gamma-aminobutyric acid(B) receptors: structure and function

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12 December 2020

Subtype-specific alterations of gamma-aminobutyric acid and glutamate in patients with major depression

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12 December 2020

Molecular targets for the myorelaxant action of diazepam.

1 reference

12 December 2020

The in vivo inhibition of GABA-transaminase by gabaculine

1 reference

12 December 2020

Nonvesicular release of neurotransmitter.

1 reference

12 December 2020

Stiff-person Syndrome.

1 reference

12 December 2020

Effect of oxidative stress on the release of [3H]GABA in cultured chick retina cells

1 reference

12 December 2020

GABA, gamma-hydroxybutyric acid, and neurological disease

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12 December 2020

Channel behavior in a gamma-aminobutyrate transporter

1 reference

12 December 2020

Stiff-man syndrome: identification of 17 beta-hydroxysteroid dehydrogenase type 4 as a novel 80-kDa antineuronal antigen

1 reference

12 December 2020

gamma-aminobutyric acid(B) receptors: first of the functional metabotropic heterodimers.

1 reference

12 December 2020

GABA mediation of the anti-aversive action of minor tranquilizers

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12 December 2020

Topiramate enhances GABA-mediated chloride flux and GABA-evoked chloride currents in murine brain neurons and increases seizure threshold.

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12 December 2020

Involvement of pallidal and nigral GABA mechanisms in the generation of tremulous jaw movements in rats.

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12 December 2020

GABAergic nigro-collicular pathways modulate the defensive behaviour elicited by midbrain tectum stimulation.

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12 December 2020

Protein kinase C regulates the interaction between a GABA transporter and syntaxin 1A

1 reference

12 December 2020

Evidence for a GABAergic projection from the substantia nigra to the ventromedial thalamus and to the superior colliculus of the rat.

1 reference

12 December 2020

GABA transaminase inhibition induces spontaneous and enhances depolarization-evoked GABA efflux via reversal of the GABA transporter.

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12 December 2020

Inhibitors of GABA metabolism

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12 December 2020

Opposite effects of low and high doses of morphine on neural substrates of aversion in the inferior colliculus.

1 reference

12 December 2020

Pharmacological and functional characterization of astrocytic GABA transport: a short review

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12 December 2020

Heterodimerization is required for the formation of a functional GABA(B) receptor

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12 December 2020

Molecular cloning and functional expression of bovine brain GABA transaminase

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12 December 2020

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12 December 2020

Immunocytochemical localization of the GABA transporter in rat brain.

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12 December 2020

Ion binding and permeation at the GABA transporter GAT1.

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12 December 2020

NNC-711, a novel potent and selective gamma-aminobutyric acid uptake inhibitor: pharmacological characterization

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12 December 2020

Anticonvulsant action in the epileptic gerbil of novel inhibitors of GABA uptake

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12 December 2020

A neuropharmacological study of the periventricular neural substrate involved in flight.

1 reference

12 December 2020

GABA(C) receptors as drug targets

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12 December 2020

Structure, function and brain localization of neurotransmitter transporters

1 reference

12 December 2020

Anxiolytic-like effect of the GABA-transaminase inhibitor vigabatrin (gamma-vinyl GABA) on rat exploratory activity.

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12 December 2020

GABAc receptors: relatively simple transmitter -gated ion channels?

1 reference

12 December 2020

Expression of a mouse brain cDNA encoding novel gamma-aminobutyric acid transporter

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12 December 2020

Signal transduction by GABA(B) receptor heterodimers

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12 December 2020

Use of inhibitors of gamma-aminobutyric acid (GABA) transaminase for the estimation of GABA turnover in various brain regions of rats: a reevaluation of aminooxyacetic acid

1 reference

12 December 2020

Defense reaction induced by microinjections of bicuculline into the inferior colliculus

1 reference

12 December 2020

Synaptic response patterns of neurons in the cortex of rat inferior colliculus

1 reference

12 December 2020

GABA transporters and GABA-transaminase as drug targets

1 reference

12 December 2020

Localization of the rho 1- and rho 2-subunit messenger RNAs in chick retina by in situ hybridization predicts the existence of gamma-aminobutyric acid type C receptor subtypes.

1 reference

12 December 2020

Effect of chronic treatment with the GABA transaminase inhibitors gamma-vinyl GABA and ethanolamine O-sulphate on the in vitro GABA release from rat hippocampus

1 reference

12 December 2020

Comparative autoradiographic distribution of central omega (benzodiazepine) modulatory site subtypes with high, intermediate and low affinity for zolpidem and alpidem.

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12 December 2020

Corelease of two fast neurotransmitters at a central synapse.

1 reference

12 December 2020

Carrier-mediated release of neurotransmitters

1 reference

12 December 2020

Ventrolateral periaqueductal gray matter and the control of tonic immobility

1 reference

12 December 2020

Cloning of the gamma-aminobutyric acid (GABA) rho 1 cDNA: a GABA receptor subunit highly expressed in the retina

1 reference

12 December 2020

What do GABA neurons really do? They make possible variability generation in relation to demand.

1 reference

12 December 2020

The synthesis of novel GABA uptake inhibitors. 1. Elucidation of the structure-activity studies leading to the choice of (R)-1-[4,4-bis(3-methyl-2-thienyl)-3-butenyl]-3-piperidinecarboxylic acid (tiagabine) as an anticonvulsant drug candidate

1 reference

12 December 2020

Topiramate: preclinical evaluation of structurally novel anticonvulsant.

1 reference

12 December 2020

The 'ABC' of GABA receptors

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12 December 2020

Ethanol and neurotransmitter interactions--from molecular to integrative effects.

1 reference

12 December 2020

Acute effects of ethanol on GABAA and glycine receptor function

1 reference

12 December 2020

Effects of lesions of amygdaloid nuclei and substantia nigra on aversive responses induced by electrical stimulation of the inferior colliculus.

1 reference

12 December 2020

The Mouse Defense Test Battery: pharmacological and behavioral assays for anxiety and panic

1 reference

12 December 2020

An mRNA encoding a putative GABA-gated chloride channel is expressed in the human cardiac conduction system

1 reference

12 December 2020

Cleft palate in mice with a targeted mutation in the gamma-aminobutyric acid-producing enzyme glutamic acid decarboxylase 67

1 reference

12 December 2020

Effects of acute and chronic fluoxetine and diazepam on freezing behavior induced by electrical stimulation of dorsolateral and lateral columns of the periaqueductal gray matter

1 reference

12 December 2020

(-)Baclofen decreases neurotransmitter release in the mammalian CNS by an action at a novel GABA receptor.

1 reference

12 December 2020

gamma-Aminobutyric acid in brain: its formation from glutamic acid.

1 reference

12 December 2020

Pre-clinical studies with the GABAergic compounds vigabatrin and tiagabine.

1 reference

12 December 2020

Neuroanatomical and neuropharmacological study of opioid pathways in the mesencephalic tectum: effect of mu(1)- and kappa-opioid receptor blockade on escape behavior induced by electrical stimulation of the inferior colliculus

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12 December 2020

The release and uptake of excitatory amino acids

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12 December 2020

Structures of gamma-aminobutyric acid (GABA) aminotransferase, a pyridoxal 5'-phosphate, and [2Fe-2S] cluster-containing enzyme, complexed with gamma-ethynyl-GABA and with the antiepilepsy drug vigabatrin

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12 December 2020

The metabolism of γ-aminobutyrate and glucose in potassium ion-stimulated brain tissue in vitro

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12 December 2020

Inactivation and inhibition of gamma-aminobutyric acid aminotransferase by conformationally restricted vigabatrin analogues

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12 December 2020

Glutamate, GABA and epilepsy

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12 December 2020

Isolation and characterization of the product of inactivation of gamma-aminobutyric acid aminotransferase by gabaculine.

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12 December 2020

The new generation of GABA enhancers. Potential in the treatment of epilepsy

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12 December 2020

GABAA and GABAB receptor site distribution in the rat central nervous system

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12 December 2020

[Affective reaction from electric stimulation of brain stem in cats]

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12 December 2020

Basic aspects of GABA-transaminase in neuropsychiatric disorders.

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12 December 2020

Calcium-dependent and -independent release of glutamate from synaptosomes monitored by continuous fluorometry

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12 December 2020

Regulation of gamma-aminobutyric acid (GABA) transporters by extracellular GABA.

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12 December 2020

Synaptic organisation of the basal ganglia

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12 December 2020

Distinct cellular distribution of GABA(B)R1 and GABA(A)alpha1 receptor immunoreactivity in the rat substantia nigra

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12 December 2020

GAT-1, a high-affinity GABA plasma membrane transporter, is localized to neurons and astroglia in the cerebral cortex.

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12 December 2020

Defensive reactions are counteracted by midazolam and muscimol and elicited by activation of glutamate receptors in the inferior colliculus of rats.

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12 December 2020

Molecular composition of GABAC receptors

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12 December 2020

Immunoisolation of GABA-specific synaptic vesicles defines a functionally distinct subset of synaptic vesicles.

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12 December 2020

Transport and Metabolism of 7-Aminobutyric Acid in Neurons and Glia: Implications for Epilepsy

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12 December 2020

Uptake of gamma-aminobutyric acid and L-glutamic acid by synaptosomes from postmortem human cerebral cortex: multiple sites, sodium dependence and effect of tissue preparation

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12 December 2020

The uptake of [3H]GABA by slices of rat cerebral cortex

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12 December 2020

Electrophysiological evidence for branching nigral projections to the thalamus and the superior colliculus

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12 December 2020

Effects of 3-hydroxy-4-amino-4,5,6,7-tetrahydro-1,2-benzisoxazol (exo-THPO) and its N-substituted analogs on GABA transport in cultured neurons and astrocytes and by the four cloned mouse GABA transporters

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12 December 2020

Resolution of two biochemically and pharmacologically distinct benzodiazepine receptors

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12 December 2020

Drug interactions at GABA(A) receptors

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12 December 2020

Neurochemical mechanisms of the defensive behavior in the dorsal midbrain

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12 December 2020

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12 December 2020

The parabrachial region as a possible region modulating simultaneously pain and tonic immobility.

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12 December 2020

Neural substrate of defensive behavior in the midbrain tectum

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12 December 2020

A GABA transporter operates asymmetrically and with variable stoichiometry

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12 December 2020

Intracellular trafficking of GABA(A) receptors

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12 December 2020

Bilateral ablation of the auditory cortex in the rat alters conditioned emotional suppression to a sound as appraised through a latent inhibition study.

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12 December 2020

Peripheral GABAB agonists stimulate gastric acid secretion in mice.

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12 December 2020

SNARE protein-dependent glutamate release from astrocytes.

1 reference

12 December 2020

Changes in the auditory-evoked potentials induced by fear-evoking stimulations

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12 December 2020

The gamma-hydroxybutyrate signalling system in brain: organization and functional implications.

1 reference

12 December 2020

Membrane anchoring of the autoantigen GAD65 to microvesicles in pancreatic beta-cells by palmitoylation in the NH2-terminal domain

1 reference

12 December 2020

Inhibition of N- and P/Q-type calcium channels by postsynaptic GABAB receptor activation in rat supraoptic neurones.

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12 December 2020

Structural and pharmacological aspects of the GABAA receptor: involvement in behavioral pathogenesis

1 reference

12 December 2020

Mechanism of action of the hypnotic zolpidem in vivo

1 reference

12 December 2020

Substantia nigra pars reticulata GABA is involved in the regulation of operant lever pressing: pharmacological and microdialysis studies

1 reference

12 December 2020

Ethanol modulation of GABA receptor-activated Cl− currents in neurons of the chick, rat and mouse central nervous system

1 reference

12 December 2020

Syntaxin 1A Inhibits GABA Flux, Efflux, and Exchange Mediated by the Rat Brain GABA Transporter GAT1

1 reference

12 December 2020

10.1007/S10571-004-6913-Z

Identifiers

DOI

1 reference

11 August 2017

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