Spilanthol from Acmella Oleracea Lowers the Intracellular Levels of cAMP Impairing NKCC2 Phosphorylation and Water Channel AQP2 Membrane Expression in Mouse Kidney (Q36026385)

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English	Spilanthol from Acmella Oleracea Lowers the Intracellular Levels of cAMP Impairing NKCC2 Phosphorylation and Water Channel AQP2 Membrane Expression in Mouse Kidney	scientific article

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scholarly article

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PMC publication ID

11 August 2017

Spilanthol from Acmella Oleracea Lowers the Intracellular Levels of cAMP Impairing NKCC2 Phosphorylation and Water Channel AQP2 Membrane Expression in Mouse Kidney (English)

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PMC publication ID

11 August 2017

phosphorylation

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inferred from title

Acmella oleracea

object named as

Acmella Oleracea

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inferred from title

1

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7 June 2020

2

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7 June 2020

4

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7 June 2020

Maria Francesca Armentano

6

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7 June 2020

Monica Carmosino

9

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7 June 2020

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Serena Milano

3

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7 June 2020

Alan Franco Barbosa

5

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7 June 2020

Giuseppe Procino

7

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7 June 2020

Maria Svelto

8

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7 June 2020

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23 May 2016

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11 August 2017

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7 June 2020

11

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7 June 2020

5

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7 June 2020

e0156021

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7 June 2020

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Creative Commons Attribution 4.0 International

23 May 2016

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4877099/fullTextXML

based on heuristic

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Kidney-targeted drug delivery systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4877099

2 October 2017

Conditionally immortalized human proximal tubular epithelial cells isolated from the urine of a healthy subject express functional calcium-sensing receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4877099

2 October 2017

NKCC2 activity is inhibited by the Bartter's syndrome type 5 gain-of-function CaR-A843E mutant in renal cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4877099

2 October 2017

Phytochemistry, Pharmacology and Toxicology of Spilanthes acmella: A Review

1 reference

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2 October 2017

β-Adrenergic receptor stimulation increases surface NKCC2 expression in rat thick ascending limbs in a process inhibited by phosphodiesterase 4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4877099

2 October 2017

Spilanthes acmella ethanolic flower extract: LC-MS alkylamide profiling and its effects on sexual behavior in male rats

1 reference

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2 October 2017

Isolation and identification of antiplasmodial N-alkylamides from Spilanthes acmella flowers using centrifugal partition chromatography and ESI-IT-TOF-MS.

1 reference

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2 October 2017

Potential effects of aggressive decongestion during the treatment of decompensated heart failure on renal function and survival

1 reference

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2 October 2017

LC-MS profiling of N-alkylamides in Spilanthes acmella extract and the transmucosal behaviour of its main bio-active spilanthol.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4877099

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Compounds from Sichuan and Melegueta peppers activate, covalently and non-covalently, TRPA1 and TRPV1 channels.

1 reference

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2 October 2017

cAMP stimulates apical exocytosis of the renal Na(+)-K(+)-2Cl(-) cotransporter NKCC2 in the thick ascending limb: role of protein kinase A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4877099

2 October 2017

Vasorelaxant and antioxidant activities of Spilanthes acmella Murr.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4877099

2 October 2017

Bioactive metabolites from Spilanthes acmella Murr.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4877099

2 October 2017

Regulation of NKCC2 by a chloride-sensing mechanism involving the WNK3 and SPAK kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4877099

2 October 2017

AQP2 exocytosis in the renal collecting duct -- involvement of SNARE isoforms and the regulatory role of Munc18b

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4877099

2 October 2017

Physiology and pathophysiology of the vasopressin-regulated renal water reabsorption

1 reference

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A comparison of donor-acceptor pairs for genetically encoded FRET sensors: application to the Epac cAMP sensor as an example

1 reference

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2 October 2017

Anti-inflammatory effect of spilanthol from Spilanthes acmella on murine macrophage by down-regulating LPS-induced inflammatory mediators

1 reference

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2 October 2017

Overview of PDEs and their regulation

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2 October 2017

Isolation and synthesis of acmellonate, a new unsaturated long chain 2-ketol ester from Spilanthes acmella

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4877099

2 October 2017

Ca2+ stimulation of adenylyl cyclase generates dynamic oscillations in cyclic AMP.

1 reference

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Cloning and characterization of the human soluble adenylyl cyclase

1 reference

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2 October 2017

Diuretic activity of Spilanthes acmella flowers in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4877099

2 October 2017

Identification of a novel A-kinase anchoring protein 18 isoform and evidence for its role in the vasopressin-induced aquaporin-2 shuttle in renal principal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4877099

2 October 2017

Short-term stimulation of the renal Na-K-Cl cotransporter (NKCC2) by vasopressin involves phosphorylation and membrane translocation of the protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4877099

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1 reference

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Loop diuretics: from the Na-K-2Cl transporter to clinical use.

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1 reference

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2 October 2017

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1 reference

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2 October 2017

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1 reference

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2 October 2017

Hormone Stimulation of Type III Adenylyl Cyclase Induces Ca2+ Oscillations in HEK-293 Cells

1 reference

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2 October 2017

Molecular cloning of the receptor for human antidiuretic hormone

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2 October 2017

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23 September 2018

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1 reference

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1 reference

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Characterization of Two Novel Missense Mutations in the AQP2 Gene Causing Nephrogenic Diabetes Insipidus

1 reference

https://pubmed.ncbi.nlm.nih.gov/27213818

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of convulsions induced by a hexanic extract of Spilanthes acmella var. oleracea in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/27213818

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PONE.0156021

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7 June 2020

2016PLoSO..1156021G

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7 June 2020

PubMed publication ID

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7 June 2020

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