Evidence-based use of methotrexate in children with rheumatic diseases: a consensus statement of the Working Groups Pediatric Rheumatology Germany (AGKJR) and Pediatric Rheumatology Austria (Q36028335)

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English	Evidence-based use of methotrexate in children with rheumatic diseases: a consensus statement of the Working Groups Pediatric Rheumatology Germany (AGKJR) and Pediatric Rheumatology Austria	scientific article

Statements

scholarly article

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Europe PubMed Central

PubMed publication ID

11 August 2017

Evidence-based use of methotrexate in children with rheumatic diseases: a consensus statement of the Working Groups Pediatric Rheumatology Germany (AGKJR) and Pediatric Rheumatology Austria (English)

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

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based on heuristic

inferred from title

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based on heuristic

inferred from title

1

object named as

Tim Niehues

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Europe PubMed Central

PubMed publication ID

11 August 2017

author name string

Gerd Horneff

2

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Europe PubMed Central

PubMed publication ID

11 August 2017

Hartmut Michels

3

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Europe PubMed Central

PubMed publication ID

11 August 2017

Michaela Sailer Höck

4

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Europe PubMed Central

PubMed publication ID

11 August 2017

Lothar Schuchmann

5

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Europe PubMed Central

PubMed publication ID

11 August 2017

Working Groups Pediatric Rheumatology Germany (AGKJR)

6

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Europe PubMed Central

PubMed publication ID

11 August 2017

Pediatric Rheumatology Austria

7

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Europe PubMed Central

PubMed publication ID

11 August 2017

publication date

2 February 2005

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Europe PubMed Central

PubMed publication ID

11 August 2017

Rheumatology International

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Europe PubMed Central

PubMed publication ID

11 August 2017

25

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Europe PubMed Central

PubMed publication ID

11 August 2017

3

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Europe PubMed Central

PubMed publication ID

11 August 2017

169-178

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Europe PubMed Central

PubMed publication ID

11 August 2017

Methotrexate for rheumatoid arthritis. Suggested guidelines for monitoring liver toxicity. American College of Rheumatology

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphadenopathy in a patient with systemic onset juvenile chronic arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methotrexate metabolism analysis in blood and liver of rheumatoid arthritis patients. Association with hepatic folate deficiency and formation of polyglutamates

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lung function and diffusing capacity for carbon monoxide in patients with juvenile chronic arthritis: effect of disease activity and low dose methotrexate therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pilot investigation of naproxen/methotrexate interaction in patients with juvenile rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Medical management of children with juvenile rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The efficacy of folic acid and folinic acid in reducing methotrexate gastrointestinal toxicity in rheumatoid arthritis. A metaanalysis of randomized controlled trials.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of oral methotrexate in children.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Recommendations by the Pediatric and Adolescent Rheumatology Study Committee on therapy with Etanercept (p75 TNF-alpha receptor immunoglobulin fusion protein. Pharmacotherapy Committee]

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methotrexate-induced hypersensitivity pneumonitis in a child with juvenile rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methotrexate-induced pneumonitis in patients with rheumatoid arthritis and psoriatic arthritis: report of five cases and review of the literature.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Psoriasis, methotrexate, and oligospermia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methotrexate for treating juvenile idiopathic arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiproliferative effects of methotrexate on peripheral blood mononuclear cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Randomized, placebo-controlled, crossover trial of low-dose oral methotrexate in children with extended oligoarticular or systemic arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methotrexate treatment in juvenile idiopathic arthritis: when is the right time to stop?

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of daily intake of folic acid on the efficacy of methotrexate therapy in children with juvenile rheumatoid arthritis. A controlled study

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is there an interaction between low doses of corticosteroids and methotrexate in patients with rheumatoid arthritis? A pharmacokinetic study in 33 patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma levels after oral methotrexate in children with juvenile rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A controlled two-centre trial of parenteral methotrexate therapy for refractory rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combinations of conventional disease-modifying antirheumatic drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Revision of the proposed classification criteria for juvenile idiopathic arthritis: Durban, 1997

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect on lung function of methotrexate and non-steroid anti-inflammatory drugs in children with juvenile rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methotrexate therapy in juvenile rheumatoid arthritis: a retrospective study

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impotence in three rheumatoid arthritis patients treated with methotrexate

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence based medicine: what it is and what it isn't

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperhomocysteinemia in children with juvenile idiopathic arthritis is not influenced by methotrexate treatment and folic acid supplementation: a pilot study

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pulmonary function in children with juvenile idiopathic arthritis and effects of methotrexate therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Duration of methotrexate treatment until partial and total remission of refractory juvenile rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methotrexate action in rheumatoid arthritis: stimulation of cytokine inhibitor and inhibition of chemokine production by peripheral blood mononuclear cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of food on the bioavailability of oral methotrexate in children.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy of low-dose methotrexate in rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolonged inhibition of DNA synthesis associated with the accumulation of methotrexate polyglutamates by cultured human cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methotrexate in rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of food on the bioavailability of low-dose methotrexate in patients with rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frequency of relapse after discontinuation of methotrexate therapy for clinical remission in juvenile rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Health care provision in pediatric rheumatology in Germany--national rheumatologic database

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Usefulness of the American College of Rheumatology recommendations for liver biopsy in methotrexate-treated rheumatoid arthritis patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The remarkable spectrum of methotrexate toxicities

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methotrexate-nonsteroidal antiinflammatory drug interaction in children with arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Folic acid supplementation prevents deficient blood folate levels and hyperhomocysteinemia during longterm, low dose methotrexate therapy for rheumatoid arthritis: implications for cardiovascular disease prevention.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-inflammatory mechanisms of methotrexate in rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adult and two children with fetal methotrexate syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of methotrexate alone or in combination with sulphasalazine on the production and circulating concentrations of cytokines and their antagonists. Longitudinal evaluation in patients with rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical, laboratory, radiographic, and histopathologic features of methotrexate-associated lung injury in patients with rheumatoid arthritis: a multicenter study with literature review

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homocysteine and folate status in methotrexate-treated patients with rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methotrexate in the treatment of juvenile rheumatoid arthritis and other pediatric rheumatoid and nonrheumatic disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Morbidity associated with long-term methotrexate therapy in juvenile rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Advances in the medical treatment of juvenile rheumatoid arthritis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A combination of etanercept and methotrexate for the treatment of refractory juvenile idiopathic arthritis: a pilot study

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A trial of etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Weekly pulse methotrexate in rheumatoid arthritis. Clinical and immunologic effects in a randomized, double-blind study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intraarticular corticosteroid injection in the management of children with chronic arthritis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methotrexate in juvenile rheumatoid arthritis. Evidence of age dependent pharmacokinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolongation and enhancement of serum methotrexate concentrations by probenecid

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphomas in rheumatoid arthritis patients treated with methotrexate: a 3-year prospective study in France.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hodgkin's disease in a patient with juvenile rheumatoid arthritis taking weekly low dose methotrexate

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The long-term effect of methotrexate therapy on the liver in patients with juvenile rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methotrexate use in rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparison of low dose methotrexate bioavailability: oral solution, oral tablet, subcutaneous and intramuscular dosing

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methotrexate in juvenile idiopathic arthritis: answers and questions

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The extended oligoarticular subtype is the best predictor of methotrexate efficacy in juvenile idiopathic arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methotrexate in the treatment of children with chronic arthritis--long-term observations of efficacy and safety

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of folic or folinic acid supplementation on the toxicity and efficacy of methotrexate in rheumatoid arthritis: a forty-eight week, multicenter, randomized, double-blind, placebo-controlled study

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A subgroup-specific evaluation of the efficacy of intraarticular triamcinolone hexacetonide in juvenile chronic arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyarticular juvenile idiopathic arthritis treated with methotrexate complicated by the development of non-Hodgkin's lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epstein-Barr virus-associated Hodgkin's lymphoma and legionella pneumophila infection complicating treatment of juvenile rheumatoid arthritis with methotrexate and cyclosporine A.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methotrexate in resistant juvenile rheumatoid arthritis. Results of the U.S.A.-U.S.S.R. double-blind, placebo-controlled trial. The Pediatric Rheumatology Collaborative Study Group and The Cooperative Children's Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Outcome of first-trimester exposure to low-dose methotrexate in eight patients with rheumatic disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toxicity and serum levels of methotrexate in children with juvenile rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discontinuation of methotrexate treatment in juvenile rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methotrexate and early postoperative complications in patients with rheumatoid arthritis undergoing elective orthopaedic surgery

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Treatment of chronic polyarthritis with methotrexate 1994--a review]

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple congenital anomalies associated with weekly low-dose methotrexate treatment of the mother

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The use of methotrexate in childhood rheumatic diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of subcutaneous methotrexate

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of low-dose oral pulse methotrexate and placebo in the treatment of rheumatoid arthritis. A controlled clinical trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hodgkin's lymphoma in systemic onset juvenile rheumatoid arthritis after treatment with low dose methotrexate

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High dose methotrexate in the treatment of refractory juvenile rheumatoid arthritis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15688190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00296-004-0537-Y

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

ResearchGate publication ID

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