Discovery of selective menaquinone biosynthesis inhibitors against Mycobacterium tuberculosis (Q36032548)

11 August 2017

Discovery of selective menaquinone biosynthesis inhibitors against Mycobacterium tuberculosis (English)

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Mycobacterium tuberculosis

11 August 2017

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Joy Debnath

1

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Scott G. Franzblau

object named as

Scott G Franzblau

6

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author name string

Shajila Siricilla

2

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11 August 2017

Bajoie Wan

3

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11 August 2017

Dean C Crick

4

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11 August 2017

Anne J Lenaerts

5

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11 August 2017

Michio Kurosu

7

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11 August 2017

language of work or name

English

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publication date

6 April 2012

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Journal of Medicinal Chemistry

11 August 2017

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11 August 2017

55

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11 August 2017

8

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11 August 2017

3739-3755

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Vitamin K2 in electron transport system: are enzymes involved in vitamin K2 biosynthesis promising drug targets?

11 August 2017

1 reference

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MenA is a promising drug target for developing novel lead molecules to combat Mycobacterium tuberculosis

2 October 2017

1 reference

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Menaquinone synthesis is critical for maintaining mycobacterial viability during exponential growth and recovery from non-replicating persistence

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375340

Mechanism-based inhibitors of MenE, an acyl-CoA synthetase involved in bacterial menaquinone biosynthesis

2 October 2017

1 reference

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Novel agents in the management of Mycobacterium tuberculosis disease

2 October 2017

1 reference

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2 October 2017

1 reference

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Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis

2 October 2017

1 reference

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Preclinical testing of the nitroimidazopyran PA-824 for activity against Mycobacterium tuberculosis in a series of in vitro and in vivo models

2 October 2017

1 reference

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Inhibitors of type II NADH:menaquinone oxidoreductase represent a class of antitubercular drugs

2 October 2017

1 reference

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A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis

2 October 2017

1 reference

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Antibacterial resistance, Wayampis Amerindians, French Guyana

2 October 2017

1 reference

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Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism

2 October 2017

1 reference

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Hypoxic response of Mycobacterium tuberculosis studied by metabolic labeling and proteome analysis of cellular and extracellular proteins

2 October 2017

1 reference

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Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase

2 October 2017

1 reference

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A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis

2 October 2017

1 reference

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Anaerobic nitrate reductase (narGHJI) activity of Mycobacterium bovis BCG in vitro and its contribution to virulence in immunodeficient mice

2 October 2017

1 reference

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Asymmetric catalysis with water: efficient kinetic resolution of terminal epoxides by means of catalytic hydrolysis

2 October 2017

1 reference

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Alternative respiratory pathways of Escherichia coli: energetics and transcriptional regulation in response to electron acceptors

2 October 2017

1 reference

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Microplate alamar blue assay versus BACTEC 460 system for high-throughput screening of compounds against Mycobacterium tuberculosis and Mycobacterium avium

2 October 2017

1 reference

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An in vitro model for sequential study of shiftdown of Mycobacterium tuberculosis through two stages of nonreplicating persistence

2 October 2017

1 reference

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Metronidazole is bactericidal to dormant cells of Mycobacterium tuberculosis

2 October 2017

1 reference

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Chemiosmotic coupling in oxidative and photosynthetic phosphorylation

2 October 2017

1 reference

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Chemiosmotic coupling in energy transduction: a logical development of biochemical knowledge

2 October 2017

1 reference

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Bacterial electron transport chains

2 October 2017

1 reference

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Basic local alignment search tool

2 October 2017

1 reference

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2 October 2017

Bacterial respiration

1 reference

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Antigenic differences between extracts of actively replicating and synchronized resting cells of Mycobacterium tuberculosis

2 October 2017

1 reference

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Unique roles of DosT and DosS in DosR regulon induction and Mycobacterium tuberculosis dormancy

2 October 2017

1 reference

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Metronidazole plus rifampin sterilizes long-term dormant Mycobacterium tuberculosis

11 July 2018

1 reference

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Ubiquinone and vitamin K in bacteria

11 July 2018

1 reference

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Inhibition of mycobacterial growth by plumbagin derivatives

11 July 2018

1 reference

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A quinoline antibiotic from Rhodococcus erythropolis JCM 6824.

23 September 2018

1 reference

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Microbiology. TB--a new target, a new drug

23 September 2018

1 reference

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Medicine. New TB drug promises shorter, simpler treatment

23 September 2018

1 reference

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The transcriptional responses of Mycobacterium tuberculosis to inhibitors of metabolism: novel insights into drug mechanisms of action

23 September 2018

1 reference

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The roles of hydrogenases 3 and 4, and the F0F1-ATPase, in H2 production by Escherichia coli at alkaline and acidic pH.

23 September 2018

1 reference

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Growth of an Escherichia coli mutant deficient in respiration

23 September 2018

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Identifiers

DOI

10.1021/JM201608G

1 reference

11 August 2017

1 reference

11 August 2017

PubMed publication ID

22449052

1 reference