Development and Characterization of a Vaginal Film Containing Dapivirine, a Non- nucleoside Reverse Transcriptase Inhibitor (NNRTI), for prevention of HIV-1 sexual transmission (Q36033871)

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Language	Label	Description	Also known as
English	Development and Characterization of a Vaginal Film Containing Dapivirine, a Non- nucleoside Reverse Transcriptase Inhibitor (NNRTI), for prevention of HIV-1 sexual transmission	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

11 August 2017

Development and Characterization of a Vaginal Film Containing Dapivirine, a Non- nucleoside Reverse Transcriptase Inhibitor (NNRTI), for prevention of HIV-1 sexual transmission (English)

1 reference

Europe PubMed Central

11 August 2017

sexual transmission

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HIV transmission

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sexually transmitted infection

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prevention of HIV/AIDS

0 references

author name string

Ayman Akil

1

1 reference

Europe PubMed Central

11 August 2017

Michael A Parniak

2

1 reference

Europe PubMed Central

11 August 2017

Charlene S Dezzuitti

3

1 reference

Europe PubMed Central

11 August 2017

Bernard J Moncla

4

1 reference

Europe PubMed Central

11 August 2017

Marilyn R Cost

5

1 reference

Europe PubMed Central

11 August 2017

Mingguang Li

6

1 reference

Europe PubMed Central

11 August 2017

Lisa Cencia Rohan

7

1 reference

Europe PubMed Central

11 August 2017

publication date

1 June 2011

1 reference

Europe PubMed Central

11 August 2017

Drug delivery and translational research

1 reference

Europe PubMed Central

11 August 2017

1

1 reference

Europe PubMed Central

11 August 2017

3

1 reference

Europe PubMed Central

11 August 2017

209-222

1 reference

Europe PubMed Central

11 August 2017

https://scigraph.springernature.com/pub.10.1007/s13346-011-0022-6

0 references

Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

In vitro and ex vivo testing of tenofovir shows it is effective as an HIV-1 microbicide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

The mutation T477A in HIV-1 reverse transcriptase (RT) restores normal proteolytic processing of RT in virus with Gag-Pol mutated in the p51-RNH cleavage site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

A novel itraconazole bioadhesive film for vaginal delivery: design, optimization, and physicodynamic characterization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

The future of HIV microbicides: challenges and opportunities.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Microbicide delivery: formulation technologies and strategies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Microbicides: chemistry, structure, and strategy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Vaginal drug delivery systems for HIV prevention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Characterization of cyclodextrin inclusion complexes of the anti-HIV non-nucleoside reverse transcriptase inhibitor UC781

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Inhibition of human immunodeficiency virus type 1 infection by the candidate microbicide dapivirine, a nonnucleoside reverse transcriptase inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Vaginal microbicides: where are we and where are we going?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Killing of Neisseria gonorrhoeae, Streptococcus agalactiae (group B streptococcus), Haemophilus ducreyi, and vaginal Lactobacillus by 3-O-octyl-sn-glycerol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Concentrations of dapivirine in the rhesus macaque and rabbit following once daily intravaginal administration of a gel formulation of [14C]dapivirine for 7 days.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Preclinical testing of candidate topical microbicides for anti-human immunodeficiency virus type 1 activity and tissue toxicity in a human cervical explant culture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Microbicide drug candidates to prevent HIV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Dose-ranging phase 1 study of TMC120, a promising vaginal microbicide, in HIV-negative and HIV-positive female volunteers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

A dual chamber model of female cervical mucosa for the study of HIV transmission and for the evaluation of candidate HIV microbicides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

In vitro microbicidal activity of the nonnucleoside reverse transcriptase inhibitor (NNRTI) UC781 against NNRTI-resistant human immunodeficiency virus type 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Acceptability of five nonoxynol-9 spermicides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

In vitro and in vivo: the story of nonoxynol 9.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Development and characterization of bioadhesive vaginal films of sodium polystyrene sulfonate (PSS), a novel contraceptive antimicrobial agent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Water dispersible microbicidal cellulose acetate phthalate film

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Blocking of cell-free and cell-associated HIV-1 transmission through human cervix organ culture with UC781.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Attenuated infectivity of HIV type 1 from epithelial cells pretreated with a tight-binding nonnucleoside reverse transcriptase inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

A tight-binding mode of inhibition is essential for anti-human immunodeficiency virus type 1 virucidal activity of nonnucleoside reverse transcriptase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Acceptability research on female-controlled barrier methods to prevent heterosexual transmission of HIV: Where have we been? Where are we going?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Acceptability of two spermicides in five countries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

A controlled trial of nonoxynol 9 film to reduce male-to-female transmission of sexually transmitted diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Vaginal microbicides: moving ahead after an unexpected setback.

1 reference

https://api.crossref.org/works/10.1007%2FS13346-011-0022-6

21 January 2018

Sustained release of microbicides by newly engineered vaginal rings

1 reference

https://api.crossref.org/works/10.1007%2FS13346-011-0022-6

21 January 2018

Polyurethane intravaginal ring for controlled delivery of dapivirine, a nonnucleoside reverse transcriptase inhibitor of HIV-1.

1 reference

https://api.crossref.org/works/10.1007%2FS13346-011-0022-6

21 January 2018

Intravaginal ring delivery of the reverse transcriptase inhibitor TMC 120 as an HIV microbicide.

1 reference

https://api.crossref.org/works/10.1007%2FS13346-011-0022-6

21 January 2018

Long-term, controlled release of the HIV microbicide TMC120 from silicone elastomer vaginal rings.

1 reference

https://api.crossref.org/works/10.1007%2FS13346-011-0022-6

21 January 2018

Safety, tolerability, and systemic absorption of dapivirine vaginal microbicide gel in healthy, HIV-negative women

1 reference

https://api.crossref.org/works/10.1007%2FS13346-011-0022-6

21 January 2018

Pharmacokinetics of 2 dapivirine vaginal microbicide gels and their safety vs. Hydroxyethyl cellulose-based universal placebo gel.

1 reference

https://api.crossref.org/works/10.1007%2FS13346-011-0022-6

21 January 2018

Design and in vitro evaluation of a novel bioadhesive vaginal drug delivery system for clindamycin phosphate

1 reference

https://api.crossref.org/works/10.1007%2FS13346-011-0022-6

21 January 2018

Why nonoxynol-9 may have failed to prevent acquisition of Neisseria gonorrhoeae in clinical trials

1 reference

https://api.crossref.org/works/10.1007%2FS13346-011-0022-6

21 January 2018

Pharmacokinetic Assessment of Dapivirine Vaginal Microbicide Gel in Healthy, HIV-Negative Women

1 reference

https://api.crossref.org/works/10.1007%2FS13346-011-0022-6

21 January 2018

Safety and Availability of Dapivirine (TMC120) Delivered from an Intravaginal Ring

1 reference

https://api.crossref.org/works/10.1007%2FS13346-011-0022-6

21 January 2018

Safety and pharmacokinetics of dapivirine delivery from matrix and reservoir intravaginal rings to HIV-negative women

1 reference

https://pubmed.ncbi.nlm.nih.gov/22708075

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of vaginal transmission of HIV-1 in hu-SCID mice by the non-nucleoside reverse transcriptase inhibitor TMC120 in a gel formulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22708075

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S13346-011-0022-6

1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

11 August 2017

ResearchGate publication ID

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