Mutasynthesis of a potent anticancer sibiromycin analogue (Q36035377)

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25 January 2020

title

Mutasynthesis of a potent anticancer sibiromycin analogue (English)

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25 January 2020

4

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25 January 2020

author name string

Isaac T Yonemoto

1

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25 January 2020

Wei Li

2

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25 January 2020

Ankush Khullar

3

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25 January 2020

Barbara Gerratana

5

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25 January 2020

publication date

23 March 2012

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25 January 2020

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25 January 2020

volume

7

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25 January 2020

issue

6

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25 January 2020

page(s)

973-977

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A four-enzyme pathway for 3,5-dihydroxy-4-methylanthranilic acid formation and incorporation into the antitumor antibiotic sibiromycin.

25 January 2020

cites work

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Mechanisms of transthyretin cardiomyocyte toxicity inhibition by resveratrol analogs

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376188

Biosynthesis, synthesis, and biological activities of pyrrolobenzodiazepines

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376188

Cloning and characterization of the biosynthetic gene cluster for tomaymycin, an SJG-136 monomeric analog

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376188

Biosynthesis of sibiromycin, a potent antitumor antibiotic

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376188

Pyrrolo[2,1-c][1,4]benzodiazepine as a scaffold for the design and synthesis of anti-tumour drugs.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376188

Benzodiazepine biosynthesis in Streptomyces refuineus.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376188

Novel cell lines derived from adult human ventricular cardiomyocytes

11 July 2018

1 reference

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SJG-136 (NSC 694501), a novel rationally designed DNA minor groove interstrand cross-linking agent with potent and broad spectrum antitumor activity: part 1: cellular pharmacology, in vitro and initial in vivo antitumor activity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376188

PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin

11 July 2018

1 reference

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Crystal structure of a covalent DNA-drug adduct: anthramycin bound to C-C-A-A-C-G-T-T-G-G and a molecular explanation of specificity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376188

Display and analysis of patterns of differential activity of drugs against human tumor cell lines: development of mean graph and COMPARE algorithm.

11 July 2018

1 reference

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Analysis of Streptomyces avermitilis genes required for avermectin biosynthesis utilizing a novel integration vector

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376188

NAD biosynthesis: identification of the tryptophan to quinolinate pathway in bacteria

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376188

Synthesis of the first example of a C2-C3/C2'-C3'-endo unsaturated pyrrolo[2,1-c][1,4]benzodiazepine dimer

23 September 2018

1 reference

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Reaction of anthramycin with DNA. Biological consequences of DNA damage in normal and xeroderma pigmentosum cell.

23 September 2018

1 reference

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Effects of daunomycin and anthramycin on electrocardiogram and mitochondrial metabolism of the rat heart

23 September 2018

1 reference

12 December 2020

Protection against anthramycin-induced toxicity in mice by coenzyme Q10

1 reference

12 December 2020

Sibanomicin, a new pyrrolo[1,4]benzodiazepine antitumor antibiotic produced by a Micromonospora sp

1 reference

12 December 2020

Effect of A-Ring Modifications on the DNA-Binding Behavior and Cytotoxicity of Pyrrolo[2,1-c][1,4]benzodiazepines†

1 reference

12 December 2020

Determination of chemically reduced pyrrolobenzodiazepine SJG-136 in human plasma by HPLC-MS/MS: application to an anticancer phase I dose escalation study

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12 December 2020

Identifiers

DOI

10.1021/CB200544U

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release_kfyncsxwtvbjlihycdyhpsr6tu

25 January 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/kfyncsxwtvbjlihycdyhpsr6tu

24 November 2022

mapped directly with Wikidata item

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25 January 2020

PubMed publication ID

22390171

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