The adhesion molecule NCAM promotes ovarian cancer progression via FGFR signalling (Q36038778)

11 August 2017

The adhesion molecule NCAM promotes ovarian cancer progression via FGFR signalling (English)

1 reference

11 August 2017

1 reference

Lorenzo Bombardelli

2

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Alessandra Decio

Alessandra Decio

3

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Giovanni D. Aletti

Giovanni Aletti

7

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Ugo Cavallaro

Ugo Cavallaro

15

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Raffaella Giavazzi

Raffaella Giavazzi

14

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Giuseppe Viale

12

Giuseppe Viale

1 reference

11 August 2017

Silvia Zecchini

1

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11 August 2017

Marco Bianchi

4

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11 August 2017

Giovanni Mazzarol

5

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11 August 2017

Fabio Sanguineti

6

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11 August 2017

Luigi Maddaluno

8

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11 August 2017

Vladimir Berezin

9

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11 August 2017

Elisabeth Bock

10

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11 August 2017

Chiara Casadio

11

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11 August 2017

Nicoletta Colombo

13

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11 August 2017

8 July 2011

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11 August 2017

EMBO Molecular Medicine

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11 August 2017

3

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11 August 2017

8

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11 August 2017

480-494

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describes a project that uses

11 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3377089/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Ovarian cancer development and metastasis

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Inhibition of FGFR2 and FGFR1 increases cisplatin sensitivity in ovarian cancer

2 October 2017

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The binding of NCAM to FGFR1 induces a specific cellular response mediated by receptor trafficking

2 October 2017

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Synthetic NCAM-derived ligands of the fibroblast growth factor receptor

2 October 2017

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Activity of the multikinase inhibitor dasatinib against ovarian cancer cells

2 October 2017

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Promising molecular targets in ovarian cancer

2 October 2017

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The biology of ovarian cancer: new opportunities for translation

2 October 2017

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2 October 2017

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Beyond chemotherapy: targeted therapies in ovarian cancer

2 October 2017

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Vascular cell adhesion molecule-1 is a regulator of ovarian cancer peritoneal metastasis

2 October 2017

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2 October 2017

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NCAM-induced focal adhesion assembly: a functional switch upon loss of E-cadherin

2 October 2017

1 reference

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NCAM-derived peptides function as agonists for the fibroblast growth factor receptor

2 October 2017

1 reference

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Loss of E-cadherin promotes ovarian cancer metastasis via alpha 5-integrin, which is a therapeutic target

2 October 2017

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The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin.

2 October 2017

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The differential role of L1 in ovarian carcinoma and normal ovarian surface epithelium

2 October 2017

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Neural cell adhesion molecule regulates the cellular response to fibroblast growth factor.

2 October 2017

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Alpha2beta1 integrin affects metastatic potential of ovarian carcinoma spheroids by supporting disaggregation and proteolysis.

2 October 2017

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The fibroblast growth factor receptor acid box is essential for interactions with N-cadherin and all of the major isoforms of neural cell adhesion molecule

2 October 2017

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Antiangiogenic and antitumor effects of SRC inhibition in ovarian carcinoma

2 October 2017

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The neural cell adhesion molecule binds to fibroblast growth factor receptor 2

2 October 2017

1 reference

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Role of lymphangiogenesis in epithelial ovarian cancer

2 October 2017

1 reference

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Role of integrin receptors for fibronectin, collagen and laminin in the regulation of ovarian carcinoma functions in response to a matrix microenvironment

2 October 2017

1 reference

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Design, construction, and characterization of a large synthetic human antibody phage display library

2 October 2017

1 reference

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Vascular endothelial growth factor-C expression and invasive phenotype in ovarian carcinomas

2 October 2017

1 reference

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Ovarian cancer metastasis: integrating insights from disparate model organisms

2 October 2017

1 reference

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Characterization of intraperitoneal, orthotopic, and metastatic xenograft models of human ovarian cancer

2 October 2017

1 reference

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Gene expression profiling of advanced ovarian cancer: characterization of a molecular signature involving fibroblast growth factor 2.

2 October 2017

1 reference

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Molecular mechanisms of NCAM function

2 October 2017

1 reference

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Cell adhesion and signalling by cadherins and Ig-CAMs in cancer

2 October 2017

1 reference

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Structure and Interactions of NCAM Ig1-2-3 Suggest a Novel Zipper Mechanism for Homophilic Adhesion

2 October 2017

1 reference

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Structural basis for a direct interaction between FGFR1 and NCAM and evidence for a regulatory role of ATP

2 October 2017

1 reference

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Cell-cell adhesion in the normal ovary and ovarian tumors of epithelial origin; an exception to the rule

2 October 2017

1 reference

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Costimulation of T cell receptor-triggered IL-2 production by Jurkat T cells via fibroblast growth factor receptor 1 upon its engagement by CD56.

2 October 2017

1 reference

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Beta 1-integrins regulate the formation and adhesion of ovarian carcinoma multicellular spheroids

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377089

The FGFR1 inhibitor PD 173074 selectively and potently antagonizes FGF-2 neurotrophic and neurotropic effects.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377089

Prevalent expression of fibroblast growth factor (FGF) receptors and FGF2 in human tumor cell lines

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377089

High-efficiency gene transfer and selection of human hematopoietic progenitor cells with a hybrid EBV/retroviral vector expressing the green fluorescence protein

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377089

Targeted mutation of Ncam to produce a secreted molecule results in a dominant embryonic lethality

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377089

Activation of the FGF receptor underlies neurite outgrowth stimulated by L1, N-CAM, and N-cadherin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377089

Targeted expression of a dominant-negative FGF receptor mutant in the epidermis of transgenic mice reveals a role of FGF in keratinocyte organization and differentiation.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377089

Targeting fibroblast growth factor receptors blocks PI3K/AKT signaling, induces apoptosis, and impairs mammary tumor outgrowth and metastasis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377089

NCAM-mimetic, FGL peptide, restores disrupted fibroblast growth factor receptor (FGFR) phosphorylation and FGFR mediated signaling in neural cell adhesion molecule (NCAM)-deficient mice

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377089

Polysialic acid glycomimetics promote myelination and functional recovery after peripheral nerve injury in mice.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377089

A peptide from the first fibronectin domain of NCAM acts as an inverse agonist and stimulates FGF receptor activation, neurite outgrowth and survival

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377089

Causal evidence for the involvement of the neural cell adhesion molecule, NCAM, in chronic stress-induced cognitive impairments.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377089

Depression-like behaviour in neural cell adhesion molecule (NCAM)-deficient mice and its reversal by an NCAM-derived peptide, FGL.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377089

Immunohistochemical study of the expression of adhesion molecules in ovarian serous neoplasms.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377089

Female mice chimeric for expression of the simian virus 40 TAg under control of the MISIIR promoter develop epithelial ovarian cancer.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377089

Blockade of FGF signaling: therapeutic promise for ovarian cancer

23 September 2018

1 reference

12 December 2020

Topography of NCAM antigenic epitopes recognized by SCLC-cluster-1 antibodies. A consensus view

1 reference

12 December 2020

Induction of FGF receptor 2-IIIb expression and response to its ligands in epithelial ovarian cancer

1 reference

12 December 2020

Expression of fibroblast growth factor (FGF)-8 isoforms and FGF receptors in human ovarian tumors

1 reference

12 December 2020

Whole genome oligonucleotide-based array comparative genomic hybridization analysis identified fibroblast growth factor 1 as a prognostic marker for advanced-stage serous ovarian adenocarcinomas

1 reference

12 December 2020

N-CAM modulates tumour-cell adhesion to matrix by inducing FGF-receptor signalling

1 reference

12 December 2020

Hot spots of antigenicity in the neural cell adhesion molecule NCAM

1 reference

12 December 2020

New potential ligand-receptor signaling loops in ovarian cancer identified in multiple gene expression studies

1 reference

12 December 2020

Beta1-integrins partly mediate binding of ovarian cancer cells to peritoneal mesothelium in vitro

1 reference

12 December 2020

Efficient inhibition of intra-peritoneal tumor growth and dissemination of human ovarian carcinoma cells in nude mice by anti-L1-cell adhesion molecule monoclonal antibody treatment

1 reference

12 December 2020

Identifiers

DOI

10.1002/EMMM.201100152

1 reference

11 August 2017

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11 August 2017

1 reference