Molecular motors and mechanisms of directional transport in neurons (Q36042285)

11 August 2017

1 reference

title

Molecular motors and mechanisms of directional transport in neurons (English)

1 reference

11 August 2017

0 references

Nobutaka Hirokawa

1

1 reference

PubMed ID

15711600

11 August 2017

Reiko Takemura

series ordinal

2

1 reference

PubMed ID

15711600

11 August 2017

language of work or name

English

0 references

publication date

1 March 2005

1 reference

Nature Reviews Neuroscience

11 August 2017

1 reference

11 August 2017

6

1 reference

11 August 2017

3

1 reference

11 August 2017

201-214

1 reference

https://scigraph.springernature.com/pub.10.1038/nrn1624

11 August 2017

0 references

cites work

Localization and translation of mRNA in dendrites and axons

1 reference

Cross-linker system between neurofilaments, microtubules, and membranous organelles in frog axons revealed by the quick-freeze, deep-etching method

21 January 2018

1 reference

Kinesin and dynein superfamily proteins and the mechanism of organelle transport

21 January 2018

1 reference

Microtubule polymerization dynamics

21 January 2018

1 reference

Polarity of axoplasmic microtubules in the olfactory nerve of the frog

21 January 2018

1 reference

Polarity orientation of microtubules in hippocampal neurons: uniformity in the axon and nonuniformity in the dendrite

21 January 2018

1 reference

Microtubule-associated protein 1C from brain is a two-headed cytosolic dynein.

21 January 2018

1 reference

Brain dynein (MAP1C) localizes on both anterogradely and retrogradely transported membranous organelles in vivo.

21 January 2018

1 reference

Golgi vesiculation and lysosome dispersion in cells lacking cytoplasmic dynein.

21 January 2018

1 reference

Dynein: An ancient motor protein involved in multiple modes of transport

21 January 2018

1 reference

Kinesin family in murine central nervous system

21 January 2018

1 reference

All kinesin superfamily protein, KIF, genes in mouse and human

21 January 2018

1 reference

Kinesin superfamily proteins and their various functions and dynamics

21 January 2018

1 reference

Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility

21 January 2018

1 reference

A novel brain ATPase with properties expected for the fast axonal transport motor

21 January 2018

1 reference

A standardized kinesin nomenclature

21 January 2018

1 reference

Stirring up development with the heterotrimeric kinesin KIF3.

21 January 2018

1 reference

Mouse models of Charcot-Marie-Tooth disease.

21 January 2018

1 reference

Biochemical and molecular characterization of diseases linked to motor proteins

21 January 2018

1 reference

Molecular motors in neuronal development, intracellular transport and diseases

21 January 2018

1 reference

Submolecular domains of bovine brain kinesin identified by electron microscopy and monoclonal antibody decoration

21 January 2018

1 reference

The C-terminal region of the stalk domain of ubiquitous human kinesin heavy chain contains the binding site for kinesin light chain.

21 January 2018

1 reference

The neuron-specific kinesin superfamily protein KIF1A is a unique monomeric motor for anterograde axonal transport of synaptic vesicle precursors

21 January 2018

1 reference

KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria

21 January 2018

1 reference

KIF3A/B: a heterodimeric kinesin superfamily protein that works as a microtubule plus end-directed motor for membrane organelle transport

21 January 2018

1 reference

Characterization of the KIF3C neural kinesin-like motor from mouse

21 January 2018

1 reference

Cloning and characterization of KAP3: a novel kinesin superfamily-associated protein of KIF3A/3B

21 January 2018

1 reference

Defect in synaptic vesicle precursor transport and neuronal cell death in KIF1A motor protein-deficient mice.

21 January 2018

1 reference

Charcot-Marie-Tooth disease type 2A caused by mutation in a microtubule motor KIF1Bbeta

21 January 2018

1 reference

Visualization of the dynamics of synaptic vesicle and plasma membrane proteins in living axons

21 January 2018

1 reference

Axonal membrane proteins are transported in distinct carriers: a two-color video microscopy study in cultured hippocampal neurons

21 January 2018

1 reference

Assembly of presynaptic active zones from cytoplasmic transport packets

21 January 2018

1 reference

Identification of an axonal determinant in the C-terminus of the sodium channel Na(v)1.2.

21 January 2018

1 reference

A targeting motif involved in sodium channel clustering at the axonal initial segment.

21 January 2018

1 reference

Identification of a Conserved Ankyrin-binding Motif in the Family of Sodium Channel α Subunits

21 January 2018

1 reference

A conserved domain in axonal targeting of Kv1 (Shaker) voltage-gated potassium channels

21 January 2018

1 reference

Continuous renewal of the axonal pathway sensor apparatus by insertion of new sensor molecules into the growth cone membrane

21 January 2018

1 reference

The polarized sorting of membrane proteins expressed in cultured hippocampal neurons using viral vectors

21 January 2018

1 reference

Growth-associated protein, GAP-43, a polypeptide that is induced when neurons extend axons, is a component of growth cones and corresponds to pp46, a major polypeptide of a subcellular fraction enriched in growth cones

21 January 2018

1 reference

Targeted disruption of mouse conventional kinesin heavy chain, kif5B, results in abnormal perinuclear clustering of mitochondria

21 January 2018

1 reference

Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I

21 January 2018

1 reference

Microtubules provide directional cues for polarized axonal transport through interaction with kinesin motor head

21 January 2018

1 reference

Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP

21 January 2018

1 reference

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

21 January 2018

1 reference

Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex

21 January 2018

1 reference

Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules

21 January 2018

1 reference

Reelin is a ligand for lipoprotein receptors

21 January 2018

1 reference

Lipoprotein receptors: new roles for ancient proteins.

21 January 2018

1 reference

Oligomeric tubulin in large transporting complex is transported via kinesin in squid giant axons

21 January 2018

1 reference

Kinesin superfamily protein 3 (KIF3) motor transports fodrin-associating vesicles important for neurite building

21 January 2018

1 reference

Functional analysis of mouse kinesin motor Kif3C.

21 January 2018

1 reference

Role of the PAR-3-KIF3 complex in the establishment of neuronal polarity

21 January 2018

1 reference

KIF2 is a new microtubule-based anterograde motor that transports membranous organelles distinct from those carried by kinesin heavy chain or KIF3A/B.

21 January 2018

1 reference

Suppression of KIF2 in PC12 cells alters the distribution of a growth cone nonsynaptic membrane receptor and inhibits neurite extension

21 January 2018

1 reference

A common mechanism for microtubule destabilizers-M type kinesins stabilize curling of the protofilament using the class-specific neck and loops

21 January 2018

1 reference

Kinesin superfamily protein 2A (KIF2A) functions in suppression of collateral branch extension.

21 January 2018

1 reference

Polarized targeting of peripheral membrane proteins in neurons

21 January 2018

1 reference

Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport

21 January 2018

1 reference

Overexpression of motor protein KIF17 enhances spatial and working memory in transgenic mice

21 January 2018

1 reference

Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites

21 January 2018

1 reference

Axon/dendrite targeting of metabotropic glutamate receptors by their cytoplasmic carboxy-terminal domains.

21 January 2018

1 reference

An evolutionarily conserved dileucine motif in Shal K+ channels mediates dendritic targeting

21 January 2018

1 reference

Identification of a cis-acting dendritic targeting element in the mRNA encoding the alpha subunit of Ca2+/calmodulin-dependent protein kinase II.

21 January 2018

1 reference

Neuronal RNA granules: a link between RNA localization and stimulation-dependent translation.

21 January 2018

1 reference

Kinesin transports RNA: isolation and characterization of an RNA-transporting granule

21 January 2018

1 reference

Novel dendritic kinesin sorting identified by different process targeting of two related kinesins: KIF21A and KIF21B

21 January 2018

1 reference

KIFC2 is a novel neuron-specific C-terminal type kinesin superfamily motor for dendritic transport of multivesicular body-like organelles.

21 January 2018

1 reference

A novel motor, KIF13A, transports mannose-6-phosphate receptor to plasma membrane through direct interaction with AP-1 complex

21 January 2018

1 reference

Adaptors for clathrin-mediated traffic

21 January 2018

1 reference

Signals for sorting of transmembrane proteins to endosomes and lysosomes

21 January 2018

1 reference

LIN-10 is a shared component of the polarized protein localization pathways in neurons and epithelia

21 January 2018

1 reference

A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain

21 January 2018

1 reference

PDZ domains in synapse assembly and signalling

21 January 2018

1 reference

PDZ domains: structural modules for protein complex assembly

21 January 2018

1 reference

The Neurospora organelle motor: a distant relative of conventional kinesin with unconventional properties

21 January 2018

1 reference

Universal and unique features of kinesin motors: insights from a comparison of fungal and animal conventional kinesins

21 January 2018

1 reference

Light chain-dependent regulation of Kinesin's interaction with microtubules

21 January 2018

1 reference

The tetratricopeptide repeat: a structural motif mediating protein-protein interactions

21 January 2018

1 reference

TPR proteins: the versatile helix

21 January 2018

1 reference

Kinesin light chains are essential for axonal transport in Drosophila

21 January 2018

1 reference

Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein

21 January 2018

1 reference

A scaffold protein JIP-1b enhances amyloid precursor protein phosphorylation by JNK and its association with kinesin light chain 1.

21 January 2018

1 reference

Amyloid beta protein precursor (AbetaPP), but not AbetaPP-like protein 2, is bridged to the kinesin light chain by the scaffold protein JNK-interacting protein 1.

21 January 2018

1 reference

The JIP group of mitogen-activated protein kinase scaffold proteins

21 January 2018

1 reference

Signal transduction by the JNK group of MAP kinases

21 January 2018

1 reference

Interaction of c-Jun amino-terminal kinase interacting protein-1 with p190 rhoGEF and its localization in differentiated neurons

21 January 2018

1 reference

Spatial, temporal and subcellular localization of islet-brain 1 (IB1), a homologue of JIP-1, in mouse brain

21 January 2018

1 reference

Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3

21 January 2018

1 reference

The reelin receptor ApoER2 recruits JNK-interacting proteins-1 and -2

21 January 2018

1 reference

JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathway

21 January 2018

1 reference

GRIP: a synaptic PDZ domain-containing protein that interacts with AMPA receptors

21 January 2018

1 reference

Kinesin light chain-independent function of the Kinesin heavy chain in cytoplasmic streaming and posterior localisation in the Drosophila oocyte.

21 January 2018

1 reference

Transport of Drosophila fragile X mental retardation protein-containing ribonucleoprotein granules by kinesin-1 and cytoplasmic dynein.

21 January 2018

1 reference

Role of phosphatidylinositol(4,5)bisphosphate organization in membrane transport by the Unc104 kinesin motor

21 January 2018

1 reference

A processive single-headed motor: kinesin superfamily protein KIF1A.

21 January 2018

1 reference

Processivity of the single-headed kinesin KIF1A through biased binding to tubulin

21 January 2018

1 reference

KIF1A alternately uses two loops to bind microtubules

21 January 2018

1 reference

Conversion of Unc104/KIF1A kinesin into a processive motor after dimerization

21 January 2018

1 reference

Direct interaction with a kinesin-related motor mediates transport of mammalian discs large tumor suppressor homologue in epithelial cells

21 January 2018

1 reference

Centractin (ARP1) associates with spectrin revealing a potential mechanism to link dynactin to intracellular organelles

21 January 2018

1 reference

beta III spectrin binds to the Arp1 subunit of dynactin

21 January 2018

1 reference

Rhodopsin's carboxy-terminal cytoplasmic tail acts as a membrane receptor for cytoplasmic dynein by binding to the dynein light chain Tctex-1

21 January 2018

1 reference

EB1 proteins regulate microtubule dynamics, cell polarity, and chromosome stability

21 January 2018

1 reference

Endocytosis of VAMP is facilitated by a synaptic vesicle targeting signal

21 January 2018

1 reference

A combination of three distinct trafficking signals mediates axonal targeting and presynaptic clustering of GAD65

21 January 2018

1 reference

Epithelial trafficking: new routes to familiar places

21 January 2018

1 reference

Polarized epithelial membrane traffic: conservation and plasticity

21 January 2018

1 reference

A novel targeting signal for proximal clustering of the Kv2.1 K+ channel in hippocampal neurons.

21 January 2018

1 reference

Real-time visualization of ZBP1 association with beta-actin mRNA during transcription and localization

21 January 2018

1 reference

Mechanisms of subcellular mRNA localization

21 January 2018

1 reference

Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility

21 January 2018

1 reference

A novel CDK5-dependent pathway for regulating GSK3 activity and kinesin-driven motility in neurons

21 January 2018

1 reference

Expression of multiple tau isoforms and microtubule bundle formation in fibroblasts transfected with a single tau cDNA.

21 January 2018

1 reference

Projection domains of MAP2 and tau determine spacings between microtubules in dendrites and axons

21 January 2018

1 reference

Rapid turnover of microtubule-associated protein MAP2 in the axon revealed by microinjection of biotinylated MAP2 into cultured neurons

21 January 2018

1 reference

Selective stabilization of tau in axons and microtubule-associated protein 2C in cell bodies and dendrites contributes to polarized localization of cytoskeletal proteins in mature neurons.

21 January 2018

1 reference

Point mutation of adenosine triphosphate-binding motif generated rigor kinesin that selectively blocks anterograde lysosome membrane transport

21 January 2018

1 reference

Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein

21 January 2018

1 reference

Left-right asymmetry and kinesin superfamily protein KIF3A: new insights in determination of laterality and mesoderm induction by kif3A-/- mice analysis

21 January 2018

1 reference

Genetic evidence for selective transport of opsin and arrestin by kinesin-II in mammalian photoreceptors

21 January 2018

1 reference

A novel microtubule-based motor protein (KIF4) for organelle transports, whose expression is regulated developmentally

21 January 2018

1 reference

KIFC3, a microtubule minus end-directed motor for the apical transport of annexin XIIIb-associated Triton-insoluble membranes

21 January 2018

1 reference

Role of KIFC3 motor protein in Golgi positioning and integration

21 January 2018

1 reference

Kinesin proteins: a phylum of motors for microtubule-based motility

21 January 2018

1 reference

Association of the kinesin motor KIF1A with the multimodular protein liprin-alpha

21 January 2018

1 reference

Intracellular transport in neurons

21 January 2018

1 reference

Two distinct mechanisms target membrane proteins to the axonal surface

31 March 2020

1 reference

The role of selective transport in neuronal protein sorting

31 March 2020

1 reference

Reeler: new tales on an old mutant mouse

31 March 2020

1 reference

KIF17 dynamics and regulation of NR2B trafficking in hippocampal neurons.

31 March 2020

1 reference

Dendritic and axonal targeting of type 5 metabotropic glutamate receptor is regulated by homer1 proteins and neuronal excitation

31 March 2020

1 reference

Alternative splicing unmasks dendritic and axonal targeting signals in metabotropic glutamate receptor 1

31 March 2020

1 reference

Identification of a cis-acting dendritic targeting element in MAP2 mRNAs.

31 March 2020

1 reference

Inhibition of activity-dependent arc protein expression in the rat hippocampus impairs the maintenance of long-term potentiation and the consolidation of long-term memory.

31 March 2020

1 reference

Characterization of MALS/Velis-1, -2, and -3: a family of mammalian LIN-7 homologs enriched at brain synapses in association with the postsynaptic density-95/NMDA receptor postsynaptic complex

31 March 2020

1 reference

Cargo binding and regulatory sites in the tail of fungal conventional kinesin

31 March 2020

1 reference

Identification of a somatodendritic targeting signal in the cytoplasmic domain of the transferrin receptor.

31 March 2020

1 reference

RNA trafficking in myelinating cells

31 March 2020

1 reference

Two cis-acting elements in the 3' untranslated region of alpha-CaMKII regulate its dendritic targeting

31 March 2020

1 reference

A Molecular Mechanism for mRNA Trafficking in Neuronal Dendrites

31 March 2020

1 reference

Activity-Dependent Trafficking and Dynamic Localization of Zipcode Binding Protein 1 and β-Actin mRNA in Dendrites and Spines of Hippocampal Neurons

31 March 2020

1 reference

Sorting mechanisms of tau and MAP2 in neurons: suppressed axonal transit of MAP2 and locally regulated microtubule binding

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRN1624

1 reference

11 August 2017

1 reference

PubMed ID

15711600