The metabolic activation and nucleic acid adducts of naturally-occurring carcinogens: recent results with ethyl carbamate and the spice flavors safrole and estragole (Q36047871)

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English	The metabolic activation and nucleic acid adducts of naturally-occurring carcinogens: recent results with ethyl carbamate and the spice flavors safrole and estragole	scientific article

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scholarly article

1 reference

Europe PubMed Central

11 August 2017

8 references

6 August 2019

20 August 2019

9 September 2019

7 November 2019

8 November 2019

26 January 2021

26 July 2022

10 October 2022

The metabolic activation and nucleic acid adducts of naturally-occurring carcinogens: recent results with ethyl carbamate and the spice flavors safrole and estragole (English)

1 reference

Europe PubMed Central

11 August 2017

flavour enhancer

1 reference

20 August 2019

1 reference

8 November 2019

1 reference

7 November 2019

2 references

ChEBI release 2020-05-28

environmental carcinogens

1 reference

26 January 2021

1 reference

1 reference

author name string

J A Miller

1

1 reference

Europe PubMed Central

11 August 2017

E C Miller

2

1 reference

Europe PubMed Central

11 August 2017

language of work or name

0 references

publication date

1 July 1983

9 references

Europe PubMed Central

11 August 2017

6 August 2019

20 August 2019

9 September 2019

7 November 2019

8 November 2019

26 January 2021

26 July 2022

10 October 2022

British Journal of Cancer

9 references

Europe PubMed Central

11 August 2017

6 August 2019

20 August 2019

9 September 2019

7 November 2019

8 November 2019

26 January 2021

26 July 2022

10 October 2022

48

1 reference

Europe PubMed Central

11 August 2017

1-15

1 reference

Europe PubMed Central

11 August 2017

1

1 reference

Europe PubMed Central

11 August 2017

https://scigraph.springernature.com/pub.10.1038/bjc.1983.151

0 references

Structure-activity studies of the carcinogenicities in the mouse and rat of some naturally occurring and synthetic alkenylbenzene derivatives related to safrole and estragole.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011423

2 October 2017

Fewer and fewer oncogenes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011423

2 October 2017

Role of depurination in mutagenesis by chemical carcinogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011423

2 October 2017

The metabolism of the naturally occurring hepatocarcinogen safrole to 1'-hydroxysafrole and the electrophilic reactivity of 1'-acetoxysafrole

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011423

2 October 2017

The carcinogenic action and metabolism of urethan and N-hydroxyurethan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011423

2 October 2017

The mutagenicities of safrole, estragole, eugenol, trans-anethole, and some of their known or possible metabolites for Salmonella typhimurium mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011423

2 October 2017

Vinyl carbamate as a promutagen and a more carcinogenic analog of ethyl carbamate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011423

2 October 2017

Defect in 3'-phosphoadenosine 5'-phosphosulfate formation in brachymorphic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011423

2 October 2017

Carcinogenic and mutagenic activities of safrole, 1'-hydroxysafrole, and some known or possible metabolites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011423

2 October 2017

Hepatocarcinogenicity of Estragole (1-Allyl-4-methoxybenzene) and 1′-Hydroxyestragole in the Mouse and Mutagenicity of 1′-Acetoxyestragole in Bacteria 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011423

2 October 2017

Formation of 3,N4-ethenocytidine moieties in RNA by vinyl chloride metabolites in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011423

2 October 2017

The metabolic activation of the carcinogen 1'-hydroxysafrole in vivo and in vitro and the electrophilic reactivities of possible ultimate carcinogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011423

2 October 2017

Modification of deoxyguanosine by chloroethylene oxide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011423

11 July 2018

The side-chain epoxidation and hydroxylation of the hepatocarcinogens safrole and estragole and some related compounds by rat and mouse liver microsomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011423

11 July 2018

Defect in 3'-phosphoadenosine 5'-phosphosulfate synthesis in brachymorphic mice. II. Tissue distribution of the defect.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011423

11 July 2018

Labeled 1,N6-ethenoadenosine and 3,N4-ethenocytidine in hepatic RNA of mice given[ethyl-1,2(-3)H or ethyl-1(-14)C]ethyl carbamate (urethan).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011423

11 July 2018

Inhibition of sulfate conjugation of N-hydroxy-2-acetylaminofluorene in isolated perfused rat liver and in the rat in vivo by pentachlorophenol and low sulfate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011423

11 July 2018

Identification of tertiary aminomethylenedioxy-propiophenones as urinary metabolites of safrole in the rat and guinea pig

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011423

11 July 2018

Lung tumor response in strain A mice as a quantitative bioassay of carcinogenic activity of some carbamates and aziridines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011423

11 July 2018

1'-Hydroxysafrole, a proximate carcinogenic metabolite of safrole in the rat and mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011423

11 July 2018

Ethyl carbamate in fermented beverages and foods. I. Naturally occurring ethylcarbamate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011423

11 July 2018

Urethan (ethyl carbamate) as a cosolvent of drugs commonly used parenterally in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011423

11 July 2018

Alkylation of DNA and proteins in mice exposed to vinyl chloride

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011423

11 July 2018

Comparative carcinogenicities and mutagenicities of vinyl carbamate, ethyl carbamate, and ethyl N-hydroxycarbamate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011423

23 September 2018

Formation of precancerous islands in rat liver and modification of DNA by ethyl carbamate: implications for its metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011423

23 September 2018

Searches for ultimate chemical carcinogens and their reactions with cellular macromolecules.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011423

23 September 2018

Fluorescent adenosine and cytidine derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/6191767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The interaction of carbon-14-labelled alkyl carbamates, labelled in the alkyl and carbonyl positions, with DNA in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/6191767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alkylation of RNA by vinyl chloride metabolites in vitro and in vivo: formation of 1-N(6)-etheno-adenosine

1 reference

https://pubmed.ncbi.nlm.nih.gov/6191767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N2 atom of guanine and N6 atom of adenine residues as sites for covalent binding of metabolically activated 1'-hydroxysafrole to mouse liver DNA in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/6191767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of sulfation in the formation of DNA adducts from N-hydroxy-2-acetylaminofluorene in rat liver in vivo. Inhibition of N-acetylated aminofluorene adduct formation by penta-chlorophenol

1 reference

https://pubmed.ncbi.nlm.nih.gov/6191767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA alkylation by vinyl chloride metabolites: etheno derivatives or 7-alkylation of guanine?

1 reference

https://pubmed.ncbi.nlm.nih.gov/6191767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of 7-carboxymethylguanine in DNA from pancreatic acinar cells exposed to azaserine

1 reference

https://pubmed.ncbi.nlm.nih.gov/6191767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/6191767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The oncogenic circle closes

1 reference

https://pubmed.ncbi.nlm.nih.gov/6191767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The myc oncogene in man and birds

1 reference

https://pubmed.ncbi.nlm.nih.gov/6191767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Still more about oncogenes

1 reference

https://pubmed.ncbi.nlm.nih.gov/6191767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/BJC.1983.151

1 reference

Europe PubMed Central

11 August 2017

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1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

11 August 2017

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