Antiaging gene Klotho enhances glucose-induced insulin secretion by up-regulating plasma membrane levels of TRPV2 in MIN6 β-cells (Q36049831)

11 August 2017

Antiaging gene Klotho enhances glucose-induced insulin secretion by up-regulating plasma membrane levels of TRPV2 in MIN6 β-cells (English)

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insulin secretion involved in cellular response to glucose stimulus

11 August 2017

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Yi Lin

1

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11 August 2017

Zhongjie Sun

series ordinal

2

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11 August 2017

language of work or name

English

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publication date

17 May 2012

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11 August 2017

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11 August 2017

153

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11 August 2017

7

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11 August 2017

3029-3039

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describes a project that uses

11 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3380305/fullTextXML

inferred from PubMed Central ID database lookup

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Klotho depletion contributes to increased inflammation in kidney of the db/db mouse model of diabetes via RelA (serine)536 phosphorylation.

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Klotho gene delivery prevents the progression of spontaneous hypertension and renal damage

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Regulation of calcium-permeable TRPV2 channel by insulin in pancreatic beta-cells

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Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1

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TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons

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Adrenomedullin stimulates nitric oxide production from primary rat hypothalamic neurons: roles of calcium and phosphatases

2 October 2017

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Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy

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The beta-glucuronidase klotho hydrolyzes and activates the TRPV5 channel

2 October 2017

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Suppression of aging in mice by the hormone Klotho

2 October 2017

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Klotho is a serum factor related to human aging

2 October 2017

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2 October 2017

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Translocation of a calcium-permeable cation channel induced by insulin-like growth factor-I

2 October 2017

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2 October 2017

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Structure of the mouse klotho gene and its two transcripts encoding membrane and secreted protein

2 October 2017

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Mutation of the mouse klotho gene leads to a syndrome resembling ageing

2 October 2017

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2 October 2017

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Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms

11 July 2018

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Secreted Klotho protein in sera and CSF: implication for post-translational cleavage in release of Klotho protein from cell membrane

11 July 2018

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Hippocampal CA1 region neurodegeneration produced by ethanol withdrawal requires activation of intrinsic polysynaptic hippocampal pathways and function of N-methyl-D-aspartate receptors

23 September 2018

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Klotho is a novel beta-glucuronidase capable of hydrolyzing steroid beta-glucuronides

23 September 2018

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TRPV2 Is a Component of Osmotically Sensitive Cation Channels in Murine Aortic Myocytes

23 September 2018

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Fractionation analysis of the subcellular distribution of GLUT-4 in 3T3-L1 adipocytes

23 September 2018

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Activation of calcium-permeable cation channel by insulin in Chinese hamster ovary cells expressing human insulin receptors

23 September 2018

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12 December 2020

Decreased insulin production and increased insulin sensitivity in the klotho mutant mouse, a novel animal model for human aging

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12 December 2020

Inhibition of proliferation of MCF-7 breast cancer cells by a blocker of Ca(2+)-permeable channel

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12 December 2020

Glucose uptake, utilization, and signaling in GLUT2-null islets

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12 December 2020

Identifiers

DOI

10.1210/EN.2012-1091

1 reference

11 August 2017

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11 August 2017

1 reference