Intracerebral Infusion of Antisense Oligonucleotides Into Prion-infected Mice (Q36053816)

11 August 2017

Intracerebral Infusion of Antisense Oligonucleotides Into Prion-infected Mice (English)

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11 August 2017

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12

Stanley B Prusiner

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11 August 2017

4

Kurt Giles

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11 August 2017

Karah Nazor Friberg

1

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11 August 2017

Gene Hung

2

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11 August 2017

Ed Wancewicz

3

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11 August 2017

Chris Black

5

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11 August 2017

Sue Freier

6

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11 August 2017

Frank Bennett

7

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11 August 2017

Stephen J Dearmond

8

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11 August 2017

Yevgeniy Freyman

9

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11 August 2017

Pierre Lessard

10

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11 August 2017

Sina Ghaemmaghami

11

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11 August 2017

7 February 2012

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Molecular Therapy. Nucleic acids

11 August 2017

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11 August 2017

1

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11 August 2017

e9

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Prion propagation and toxicity in vivo occur in two distinct mechanistic phases

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381600

RNA targeting therapeutics: molecular mechanisms of antisense oligonucleotides as a therapeutic platform

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381600

Measuring prions by bioluminescence imaging

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381600

Single treatment with RNAi against prion protein rescues early neuronal dysfunction and prolongs survival in mice with prion disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381600

Cell division modulates prion accumulation in cultured cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381600

Phosphorothioate oligonucleotides reduce PrP levels and prion infectivity in cultured cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381600

Lentivector-mediated RNAi efficiently suppresses prion protein and prolongs survival of scrapie-infected mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381600

Antisense oligonucleotide therapy for neurodegenerative disease.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381600

Potent antiscrapie activities of degenerate phosphorothioate oligonucleotides

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381600

Sequence-dependent cytotoxicity of second-generation oligonucleotides.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381600

Determination of the role of the human RNase H1 in the pharmacology of DNA-like antisense drugs

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381600

Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381600

Efficient and specific down-regulation of prion protein expression by RNAi

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381600

Specific inhibition of pathological prion protein accumulation by small interfering RNAs

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381600

Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381600

Regional mapping of prion proteins in brain

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381600

Heritable disorder resembling neuronal storage disease in mice expressing prion protein with deletion of an alpha-helix

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381600

High prion and PrPSc levels but delayed onset of disease in scrapie-inoculated mice heterozygous for a disrupted PrP gene

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381600

The sequential development of abnormal prion protein accumulation in mice with Creutzfeldt-Jakob disease

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381600

Prion clearance in bigenic mice.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381600

Postexposure prophylaxis against prion disease with a stimulator of innate immunity

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381600

Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-alpha expression

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381600

A novel solid support for synthesis of oligonucleotide 3'-phosphorothioate monoesters

23 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23344724

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/MTNA.2011.6

1 reference

release_2swmlzgqbfcl3kycwoxiyxvxye

11 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/2swmlzgqbfcl3kycwoxiyxvxye

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

11 August 2017

1 reference