Formation of omeprazole sulphone but not 5-hydroxyomeprazole is inhibited by grapefruit juice (Q36055042)

11 August 2017

Formation of omeprazole sulphone but not 5-hydroxyomeprazole is inhibited by grapefruit juice (English)

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11 August 2017

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W Tassaneeyakul

1

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11 August 2017

S Vannaprasaht

series ordinal

2

1 reference

11 August 2017

Y Yamazoe

series ordinal

3

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11 August 2017

language of work or name

English

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publication date

1 February 2000

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British Journal of Clinical Pharmacology

11 August 2017

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11 August 2017

49

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11 August 2017

2

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11 August 2017

139-144

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Identification of human liver cytochrome P450 isoforms mediating omeprazole metabolism

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014902

Grapefruit juice-drug interactions

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014902

Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents. Decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarins.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014902

Carbamazepine treatment induces the CYP3A4 catalysed sulphoxidation of omeprazole, but has no or less effect on hydroxylation via CYP2C19.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014902

Effects of grapefruit juice ingestion--pharmacokinetics and haemodynamics of intravenously and orally administered felodipine in healthy men.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014902

Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014902

Inhibitory effect of grapefruit juice and its bitter principal, naringenin, on CYP1A2 dependent metabolism of caffeine in man.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014902

Identification of human liver cytochrome P450 isoforms mediating secondary omeprazole metabolism

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014902

Interphenotype differences in disposition and effect on gastrin levels of omeprazole—suitability of omeprazole as a probe for CYP2C19

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014902

Clinical experience with omeprazole: assessment of efficacy and safety.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014902

Inhibition of the sulfoxidation of omeprazole by ketoconazole in poor and extensive metabolizers of S-mephenytoin.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014902

Slow omeprazole metabolizers are also poor S-mephenytoin hydroxylators.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014902

Grapefruit juice and cimetidine inhibit stereoselective metabolism of nitrendipine in humans

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014902

Disposition kinetics and metabolism of omeprazole in extensive and poor metabolizers of S-mephenytoin 4'-hydroxylation recruited from an Oriental population.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014902

Plasma concentrations of triazolam are increased by concomitant ingestion of grapefruit juice

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014902

Interaction between grapefruit juice and midazolam in humans*

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014902

Simultaneous determination of omeprazole and its metabolites in plasma and urine by reversed-phase high-performance liquid chromatography with an alkaline-resistant polymer-coated C18 column

23 September 2018

1 reference

12 December 2020

Grapefruit juice--felodipine interaction: mechanism, predictability, and effect of naringin

1 reference

12 December 2020

Grapefruit juice inhibits 7-hydroxylation of coumarin in healthy volunteers

1 reference

12 December 2020

Inhibition of 17β-estradiol metabolism by grapefruit juice in ovariectomized women

1 reference

12 December 2020

Disposition of intravenous and oral cyclosporine after administration with grapefruit juice

1 reference

12 December 2020

The hydroxylation of omeprazole correlates with S-mephenytoin metabolism: a population study

1 reference

12 December 2020

Grapefruit juice alters terfenadine pharmacokinetics, resulting in prolongation of repolarization on the electrocardiogram

1 reference

12 December 2020

Pharmacokinetics of omeprazole (a substrate of CYP2C19) and comparison with two mutant alleles, C gamma P2C19m1 in exon 5 and C gamma P2C19m2 in exon 4, in Japanese subjects

1 reference

12 December 2020

Assays of omeprazole metabolism as a substrate probe for human CYP isoforms

1 reference

12 December 2020

Specific CYP3A4 inhibitors in grapefruit juice: furocoumarin dimers as components of drug interaction

1 reference

12 December 2020

The character of inhibition of the metabolism of 1,2-benzopyrone (coumarin) by grapefruit juice in human

1 reference

12 December 2020

10.1046/J.1365-2125.2000.00122.X

Identifiers

DOI

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11 August 2017

1 reference

11 August 2017

PubMed publication ID

10671908

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